AriMocloMol Maleic Acid
- CAS No.
- 289893-26-1
- Chemical Name:
- AriMocloMol Maleic Acid
- Synonyms
- BRX220;BRX-220;BRX-345;BRX345.;BRX 220;BRX 345;AriMocloMol Maleic Acid;(2R)-Arimoclomol maleate;(2R)-Arimoclomol Maleic Acid;ARIMOCLOMOL MALEATE (BRX-220)
- CBNumber:
- CB02695637
- Molecular Formula:
- C18H24ClN3O7
- Molecular Weight:
- 429.85206
- MDL Number:
- MOL File:
- 289893-26-1.mol
- MSDS File:
- SDS
| Melting point | >131°C (dec.) |
|---|---|
| storage temp. | Amber Vial, -20°C Freezer, Under inert atmosphere |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| color | White to Off-White |
| Water Solubility | H2O: 2mg/mL, clear |
| FDA UNII | 18D1V854HG |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
AriMocloMol Maleic Acid price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | A771270 | (2R)-ArimoclomolMaleicAcid | 289893-26-1 | 5mg | $1205 | 2021-12-16 | Buy |
| ChemScene | CS-0062887 | Arimoclomolmaleate 99.96% | 289893-26-1 | 5mg | $50 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA159627 | (2R)-Arimoclomol maleate | 289893-26-1 | 1mg | $70 | 2021-12-16 | Buy |
| ChemScene | CS-0062887 | Arimoclomolmaleate 99.96% | 289893-26-1 | 10mg | $90 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA159627 | (2R)-Arimoclomol maleate | 289893-26-1 | 2mg | $100 | 2021-12-16 | Buy |
AriMocloMol Maleic Acid Chemical Properties,Uses,Production
Uses
AriMocloMol Maleic Acid is a orally administered drug used to treat amyotrophic lateral sclerosis and was later discovered to be a potential insulin resistance treatment and diabetic complications.
Biological Activity
Arimoclomol is an orally available, CNS-penetrant coinducer of he at shock proteins (HSPs), notably HSP70, th at exhibits in vivo efficay in disease models of diabetes, Gaucher disease (GD), sporadic inclusion body myositis (sIBM), and neurological disorders, including amyotrophic lateral sclerosis (ALS) and Niemann-Pick disease type C1 (NPC1). Note: arimoclomol maleate and citrate salt forms are known as BRX-220 and BRX-345, respectively.
in vivo
Arimoclomol (BRX-220; 20 mg/kg; orally administered for 5 d) has a protective effect against cholecystokinin-octapeptide (CCK)-induced acute pancreatitis[1].
| Animal Model: | Male Wistar rats weighing 240 to 270 g[1] |
| Dosage: | 20 mg/kg |
| Administration: | Administered intragastrically, for 5 days |
| Result: | Had a protective effect against CCK-induced acute pancreatitis. |
IC 50
HSP
AriMocloMol Maleic Acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21628 | 55 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32190 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38633 | 58 | |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Shanghai Boyle Chemical Co., Ltd. | sales@boylechem.com | China | 2922 | 55 | |
| J & K SCIENTIFIC LTD. | 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. | 17702719238 17702719238 | sales@sun-shinechem.com | China | 1015 | 64 |
View Lastest Price from AriMocloMol Maleic Acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-18 | Arimoclomol maleate
289893-26-1
|
US $39.00-147.00 / mg | 99.98% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-11-18 | Arimoclomol maleate
289893-26-1
|
US $39.00-147.00 / mg | 99.98% | 10g | TargetMol Chemicals Inc. |
-
- Arimoclomol maleate
289893-26-1
- US $39.00-147.00 / mg
- 99.98%
- TargetMol Chemicals Inc.
-
- Arimoclomol maleate
289893-26-1
- US $39.00-147.00 / mg
- 99.98%
- TargetMol Chemicals Inc.