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ChemicalBook >> CAS DataBase List >>2-Amino-1-[2-(4-fluorophenyl)-3-[(4-fluorophenyl)amino]-5,6-dihydro-8,8-dimethylimidazo[1,2-a]pyrazin-7(8H)-yl]ethanone

2-Amino-1-[2-(4-fluorophenyl)-3-[(4-fluorophenyl)amino]-5,6-dihydro-8,8-dimethylimidazo[1,2-a]pyrazin-7(8H)-yl]ethanone

2-Amino-1-[2-(4-fluorophenyl)-3-[(4-fluorophenyl)amino]-5,6-dihydro-8,8-dimethylimidazo[1,2-a]pyrazin-7(8H)-yl]ethanone Structure
2-Amino-1-[2-(4-fluorophenyl)-3-[(4-fluorophenyl)amino]-5,6-dihydro-8,8-dimethylimidazo[1,2-a]pyrazin-7(8H)-yl]ethanone structure
CAS No.
1261113-96-5
Chemical Name:
2-Amino-1-[2-(4-fluorophenyl)-3-[(4-fluorophenyl)amino]-5,6-dihydro-8,8-dimethylimidazo[1,2-a]pyrazin-7(8H)-yl]ethanone
Synonyms
GNF-776;KAF-156;GNF-156);GN-Pf-5069;Ganaplacide (KAF156;2-Amino-1-[2-(4-fluorophenyl)-3-[(4-fluorophenyl)amino]-5,6...;2-Amino-1-[2-(4-fluorophenyl)-3-[(4-fluorophenyl)amino]-5,6-dihydro-8,8-dimethylimidazo[1,2-a]pyrazin-7(8H)-yl]ethanone;Ethanone, 2-amino-1-[2-(4-fluorophenyl)-3-[(4-fluorophenyl)amino]-5,6-dihydro-8,8-dimethylimidazo[1,2-a]pyrazin-7(8H)-yl]-
CBNumber:
CB02717085
Molecular Formula:
C22H23F2N5O
Molecular Weight:
411.45
MDL Number:
MFCD28502124
MOL File:
1261113-96-5.mol
Last updated:2025-04-17 18:22:24
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2-Amino-1-[2-(4-fluorophenyl)-3-[(4-fluorophenyl)amino]-5,6-dihydro-8,8-dimethylimidazo[1,2-a]pyrazin-7(8H)-yl]ethanone Properties

FDA UNII 85VMN9JU7A

2-Amino-1-[2-(4-fluorophenyl)-3-[(4-fluorophenyl)amino]-5,6-dihydro-8,8-dimethylimidazo[1,2-a]pyrazin-7(8H)-yl]ethanone Chemical Properties,Uses,Production

Uses

GNF-156 is used in the development process for discovery and clinical advancement of modern antimalarials.

in vivo

Ganaplacide (KAF156) displays cidal activity against mature Plasmodium falciparum gametocytes and thus blocks parasite transmission to Anopheles mosquitoes[1].
Ganaplacide (KAF156) (1-15 mg/kg; p.o.) is fully protective in a causal prophylactic mouse model of malaria[1].

Animal Model:Mice (causal prophylactic rodent malaria model)[1]
Dosage:1-15 mg/kg
Administration:p.o.
Result:A single oral dose of 10 mg of KAF156/kg administered 2 h before infection was fully protective.

2-Amino-1-[2-(4-fluorophenyl)-3-[(4-fluorophenyl)amino]-5,6-dihydro-8,8-dimethylimidazo[1,2-a]pyrazin-7(8H)-yl]ethanone Preparation Products And Raw materials

Raw materials

Preparation Products

2-Amino-1-[2-(4-fluorophenyl)-3-[(4-fluorophenyl)amino]-5,6-dihydro-8,8-dimethylimidazo[1,2-a]pyrazin-7(8H)-yl]ethanone Suppliers

Global( 29)Suppliers
Supplier Tel Email Country ProdList Advantage
Biochempartner 		0086-13720134139 candy@biochempartner.com CHINA 965 58
Shandong chuangyingchemical Co., Ltd. 		18853181302 sale@chuangyingchem.com CHINA 5906 58
TargetMol Chemicals Inc. 		+17819995354 marketing@targetmol.com United States 32298 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6312 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418684 +8618949823763 sales@tnjchem.com China 25356 58
Nantong HI-FUTURE Biology Co., Ltd. 		+undefined18051384581 sales@chemhifuture.com China 3135 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525 masar@topule.com China 8467 58
TargetMol Chemicals Inc. 		+17819995354 marketing@targetmol.com United States 19904 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
Shanghai Taifu Pharmaceutical Technology Co. LTD 021-58111238 18930958102 sales@taifupharm.com China 510 55
Supplier Advantage
Biochempartner 		58
Shandong chuangyingchemical Co., Ltd. 		58
TargetMol Chemicals Inc. 		58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
Nantong HI-FUTURE Biology Co., Ltd. 		58
Wuhan Topule Biopharmaceutical Co., Ltd 		58
TargetMol Chemicals Inc. 		58
Amadis Chemical Company Limited 		58
Shanghai Taifu Pharmaceutical Technology Co. LTD 55

View Lastest Price from 2-Amino-1-[2-(4-fluorophenyl)-3-[(4-fluorophenyl)amino]-5,6-dihydro-8,8-dimethylimidazo[1,2-a]pyrazin-7(8H)-yl]ethanone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ganaplacide pictures 2024-10-28 Ganaplacide
1261113-96-5
 US $2780.00-3700.00 / mg 10g TargetMol Chemicals Inc.
  • Ganaplacide pictures
  • Ganaplacide
    1261113-96-5
  • US $2780.00-3700.00 / mg
  • TargetMol Chemicals Inc.
2-Amino-1-[2-(4-fluorophenyl)-3-[(4-fluorophenyl)amino]-5,6-dihydro-8,8-dimethylimidazo[1,2-a]pyrazin-7(8H)-yl]ethanone KAF-156 GNF-156) Ganaplacide (KAF156 2-Amino-1-[2-(4-fluorophenyl)-3-[(4-fluorophenyl)amino]-5,6... Ethanone, 2-amino-1-[2-(4-fluorophenyl)-3-[(4-fluorophenyl)amino]-5,6-dihydro-8,8-dimethylimidazo[1,2-a]pyrazin-7(8H)-yl]- GNF-776 GN-Pf-5069 1261113-96-5