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N-Methylbenzamide

N-Methylbenzamide structure

CAS No.: 613-93-4

Chemical Name:: N-Methylbenzamide

Synonyms: 1MVR;N-Methylbenzenamide;Benzamide, N-methyl-;n-methyl-benzamid;N-METHYLBENZAMIDE;N-Methylbenzamide, 95%;N-METHYLBENZAMIDE, 99+%;N-Methylbenzamide;n-methylbenzenecarboxamide;N-MethylbenzaMide, 99+% 10GR

CBNumber:: CB0273752

Molecular Formula:: C8H9NO

Molecular Weight:: 135.16

MDL Number:: MFCD00011642

MOL File:: 613-93-4.mol

MSDS File:: SDS

Last updated:2025-02-06 17:54:05

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N-Methylbenzamide Properties

Melting point	76-78 °C (lit.)
Boiling point	167 °C/11 mmHg (lit.)
Density	1.1031 (rough estimate)
refractive index	1.5589 (estimate)
storage temp.	Sealed in dry,Room Temperature
solubility	ethanol: soluble50mg/mL, clear, yellow-green
pka	15.00±0.46(Predicted)
form	Solid
color	White to off-white
Water Solubility	Insoluble in water.
InChI	InChI=1S/C8H9NO/c1-9-8(10)7-5-3-2-4-6-7/h2-6H,1H3,(H,9,10)
InChIKey	NCCHARWOCKOHIH-UHFFFAOYSA-N
SMILES	C(NC)(=O)C1=CC=CC=C1
CAS DataBase Reference	613-93-4(CAS DataBase Reference)
FDA UNII	K3ED781E08
EPA Substance Registry System	N-Methylbenzamide (613-93-4)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P280a-P304+P340-P305+P351+P338-P405-P501a

Hazard Codes

Risk Statements

20/21/22-22

Safety Statements

24/25

WGK Germany

RTECS

CV5570000

TSCA

Yes

HS Code

29242990

NFPA 704

	0
1		0

N-Methylbenzamide price More Price(21)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	222798	N-Methylbenzamide ≥99%	613-93-4	5g	$68.1	2023-01-07	Buy
Sigma-Aldrich	222798	N-Methylbenzamide ≥99%	613-93-4	10g	$116	2023-01-07	Buy
Alfa Aesar	A18057	N-Methylbenzamide, 99%	613-93-4	5g	$57.65	2024-03-01	Buy
Alfa Aesar	A18057	N-Methylbenzamide, 99%	613-93-4	25g	$189.65	2024-03-01	Buy
Alfa Aesar	A18057	N-Methylbenzamide, 99%	613-93-4	100g	$745	2023-06-20	Buy

Product number	Packaging	Price	Buy
222798	5g	$68.1	Buy
222798	10g	$116	Buy
A18057	5g	$57.65	Buy
A18057	25g	$189.65	Buy
A18057	100g	$745	Buy

N-Methylbenzamide Chemical Properties,Uses,Production

Chemical Properties

N-methylbenzamide is an off-white crystalline solid.

Uses

N-Methylbenzamide is an important pesticide intermediate. It acts as a potent PDE10A (phosphodiesterase with a remarkable localization as the protein is abundant only in brain tissue) inhibitor.

Synthesis Reference(s)

Synthetic Communications, 7, p. 549, 1977 DOI: 10.1080/00397917709409275
Tetrahedron Letters, 30, p. 451, 1989 DOI: 10.1016/S0040-4039(00)95225-0

Air & Water Reactions

Insoluble in water.

Reactivity Profile

N-METHYLBENZAMIDE is an amide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).

Fire Hazard

Flash point data concerning N-METHYLBENZAMIDE are not available, however, N-METHYLBENZAMIDE is probably combustible.

Synthesis

Add benzoic acid (977 mg, 8 mmol), dry DCM (20 mL) and catalytic amount of DMF in a 100 mL round-bottom flask. Cool the reaction mixture to 0°C and stir for 5 minutes. Add (COCl)2 (0.89 mL, 1.3 equiv.) dropwise to the reaction mixture and stir at room temperature for 4 hours. Concentrate the resulting mixture under reduced pressure to obtain acid chloride. Add catalytic amount of 4-dimethylaminopyridine, dry DCM (15 mL), MeNH2 (2 (M) in THF) (5.19 mL, 1.3 equiv.) and Et3N (1.56 mL, 1.4 equiv.) to the mixture in a 100 mL round-bottom flask. Cool the reaction mixture to 0°C. Add acid chloride (1.0 equiv.) dropwise at 0°C. Stir the reaction mixture at room temperature for 12 hours. Add water (40 mL) and seperate the organic layer. Extract the aqueous layer with DCM (3 x 30 mL). Wash the combined organic layer with saturated aqueous NaHCO3 (30 mL) solution followed by water (30 mL). Dry the organic layer over Na2SO4 and concentrated under reduced pressure. Purify the crude mass by silica gel column chromatography (20% ethyl acetate in hexane as eluent) to obtain N-methylbenzamide. DOI: 10.1002/anie.202203539

N-Methylbenzamide Preparation Products And Raw materials

Raw materials

Preparation Products

N-Methylbenzamide Suppliers

Global( 205)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
XINGTAI XINGJIU NEW MATERIAL TECHNOLOGY CO., LTD	+8617731987558	xingjiu@xingjiubiotech.com	China	989	58
Xiamen Wonderful Bio Technology Co., Ltd.	+8613043004613	Sara@xmwonderfulbio.com	China	283	58
Hebei Yanxi Chemical Co., Ltd.	+8617531153977	allison@yan-xi.com	China	5854	58
Nanjing Deda New Material Technology Co., Ltd	+8613223293093	bella@njdeda.com	China	80	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	sales1@chuanghaibio.com	China	5868	58
Guangzhou Tengyue Chemical Co., Ltd.	+86-86-18148706580 +8618826483838	evan@tyvovo.com	China	146	58
Anhui Ruihan Technology Co., Ltd	+8617756083858	daisy@anhuiruihan.com	China	973	58
Hebei Longbang Technology Co., LTD	+86-18633929156 +86-18633929156	admin@hblongbang.com	China	972	58
Shanghai Likang New Materials Co., Limited	+86-16631818819 +86-17736933208	3684455296@qq.com	China	9300	58
Hebei Yiduo Import and Export Co., Ltd.		joycedemei1505@outlook.com	China	204	58

Supplier	Advantage
XINGTAI XINGJIU NEW MATERIAL TECHNOLOGY CO., LTD	58
Xiamen Wonderful Bio Technology Co., Ltd.	58
Hebei Yanxi Chemical Co., Ltd.	58
Nanjing Deda New Material Technology Co., Ltd	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Guangzhou Tengyue Chemical Co., Ltd.	58
Anhui Ruihan Technology Co., Ltd	58
Hebei Longbang Technology Co., LTD	58
Shanghai Likang New Materials Co., Limited	58
Hebei Yiduo Import and Export Co., Ltd.	58

Synthesis and Applications of N-Methylbenzamide
N-methylbenzamide is an amide derived from benzamide. This organic compound has unique chemical properties and versatility.
Mar 25，2024

Synthesis and Application of N-Methylbenzamide
N-Methylbenzamide is an important pesticide intermediate.
Nov 21，2022

View Lastest Price from N-Methylbenzamide manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-04-21	N-Methylbenzamide 613-93-4	US $100.00 / kg	1kg	99% Purity (What/sapp: +86 18145728414)	1000 Tons/Month	Guangzhou Tengyue Chemical Co., Ltd.
2025-04-04	N-METHYLBENZAMIDE 613-93-4	US $0.00-0.00 / KG	1KG	98%	1ton	Henan Aochuang Chemical Co.,Ltd.
2025-03-28	N-Methylbenzamide 613-93-4	US $6.00 / kg	1kg	More than 99%	2000KG/Month	Hebei Longbang Technology Co., Ltd

N-Methylbenzamide
613-93-4
US $100.00 / kg
99% Purity (What/sapp: +86 18145728414)
Guangzhou Tengyue Chemical Co., Ltd.

N-METHYLBENZAMIDE
613-93-4
US $0.00-0.00 / KG
98%
Henan Aochuang Chemical Co.,Ltd.

N-Methylbenzamide
613-93-4
US $6.00 / kg
More than 99%
Hebei Longbang Technology Co., Ltd

N-Methylbenzamide Spectrum

N-Methylbenzamide(613-93-4)MS N-Methylbenzamide(613-93-4)¹HNMR N-Methylbenzamide(613-93-4)¹³CNMR N-Methylbenzamide(613-93-4)IR1 N-Methylbenzamide(613-93-4)IR2 N-Methylbenzamide(613-93-4)Raman

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