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2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid

2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid Structure
2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid structure
CAS No.
123021-85-2
Chemical Name:
2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid
Synonyms
GPR35 agonist 3;GPR35 Agonist, Compound 10;GPR35 Agonist, Compound 10 >=98% (HPLC);2-(4-((2,4-dioxothiazolidin-5-ylidene)methyl)phenoxy)acetic acid;2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid;Acetic acid, 2-[4-[(2,4-dioxo-5-thiazolidinylidene)methyl]phenoxy]-;2-{4-[(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]p henoxy}acetic acid
CBNumber:
CB02750482
Molecular Formula:
C12H9NO5S
Molecular Weight:
279.27
MDL Number:
MFCD01835940
MOL File:
123021-85-2.mol
MSDS File:
SDS
Last updated:2023-04-23 13:52:06
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2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid Properties

Density 1.550±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: ≥5mg/mL at ~60°C
form powder
pka 3.08±0.10(Predicted)
color white to tan

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P305+P351+P338
Hazard Codes  Xi
Risk Statements  36
Safety Statements  26
WGK Germany  3

2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML0174 GPR35 Agonist, Compound 10 ≥98% (HPLC) 123021-85-2 5mg $132 2024-03-01 Buy
Sigma-Aldrich SML0174 GPR35 Agonist, Compound 10 ≥98% (HPLC) 123021-85-2 25mg $551 2024-03-01 Buy
American Custom Chemicals Corporation CHM0988248 2-[4-[(2,4-DIOXO-5-THIAZOLIDINYLIDENE)METHYL]PHENOXY]-ACETIC ACID 95.00% 123021-85-2 5MG $502.25 2021-12-16 Buy
aablocks AA01KCLD {4-[(E)-(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]phenoxy}aceticacid 123021-85-2 5g $1273 2021-12-16 Buy
Product number Packaging Price Buy
SML0174 5mg $132 Buy
SML0174 25mg $551 Buy
CHM0988248 5MG $502.25 Buy
AA01KCLD 5g $1273 Buy

2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid Chemical Properties,Uses,Production

Uses

GPR35 Agonist, Compound 10, may be used in GPR35-mediated cell signaling studies.

Biochem/physiol Actions

GPR35 agonist Compound 10 is a GPR35 agonist the binds with higher affinity than other known agonists, such as kynurenic acid and zaprinast. Compound 10 was more potent than zaniprast (pEC50 = 5.3 vs 4.18) for recombinantly expressed human GPR35, and unlike zaprinast, is equipotent for human and rat GPR35

2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid Suppliers

Global( 14)Suppliers
Supplier Tel Email Country ProdList Advantage
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 57511 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Shanghai Rechem science Co., Ltd. 21-31433387 15618786686 sales@rechemscience.com China 2966 58
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136 info@SuperLan-chem.com China 9941 58
MQ (shanghai) Pharmaceuticals Co., Ltd. 13761635123 1014988033@qq.com China 4977 55
Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 44843 58
Nanjing Shizhou Biology Technology Co.,Ltd 13675144456 sean.lv@synzest.com China 10787 58
Hefei Mokai Pharmaceutical Technology Co., Ltd 18130062233 3362556465@qq.com China 8000 58
Bide Pharmatech Ltd. 15221909166 13681763483 huahuanhuan@bidepharm.com China 63720 58
Guangdong Shengke Biochemical Technology Co., Ltd. 189-25112307 18925113981 3809205144@qq.com China 10000 58
Supplier Advantage
Aladdin Scientific 		58
Sigma-Aldrich 80
Shanghai Rechem science Co., Ltd. 58
Shanghai Chaolan Chemical Technology Center 58
MQ (shanghai) Pharmaceuticals Co., Ltd. 55
Energy Chemical 58
Nanjing Shizhou Biology Technology Co.,Ltd 58
Hefei Mokai Pharmaceutical Technology Co., Ltd 58
Bide Pharmatech Ltd. 58
Guangdong Shengke Biochemical Technology Co., Ltd. 58
2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid GPR35 Agonist, Compound 10 2-(4-((2,4-dioxothiazolidin-5-ylidene)methyl)phenoxy)acetic acid GPR35 Agonist, Compound 10 >=98% (HPLC) 2-{4-[(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]p henoxy}acetic acid GPR35 agonist 3 Acetic acid, 2-[4-[(2,4-dioxo-5-thiazolidinylidene)methyl]phenoxy]- 123021-85-2