Anti-CDC14B antibody produced in rabbit

Biological Activity

CDC14B (cell division cycle 14B) gene encodes a member of the dual specificity protein tyrosine phosphatase family. It is localized to the interphase centrosome and functions in centrosome separation. In vitro, it binds to and stabilizes microtubules. It regulates spindle assembly and disassembly during mitosis. It induces the activation of the ubiquitin ligase APC/CCdh1 after translocation from the nucleolus to the nucleoplasm, in response to genotoxic stress in G2.