Trifluoroacetamide
- CAS No.
- 354-38-1
- Chemical Name:
- Trifluoroacetamide
- Synonyms
- 2,2,2-TRIFLUOROACETAMIDE;Acetamide, 2,2,2-trifluoro-;CF3CONH2;Triflouroacetamide;Three-;TRIFLUOROACETAMIDE;2-TriflouroacetaMide;Trifluoroacetamide98%;Three fluoroacetaMide;2,2,2-Trifluoracetamid
- CBNumber:
- CB0291820
- Molecular Formula:
- C2H2F3NO
- Molecular Weight:
- 113.04
- MDL Number:
- MFCD00008008
- MOL File:
- 354-38-1.mol
- MSDS File:
- SDS
Melting point | 65-70 °C (lit.) |
---|---|
Boiling point | 162.5 °C (lit.) |
Density | 1.4176 (estimate) |
Flash point | 162-164°C |
storage temp. | Store below +30°C. |
solubility | 460 g/L (20°C) |
form | Crystalline Powder or Crystals |
pka | 12.33±0.50(Predicted) |
color | White to pale yellow or beige |
PH | 3.6 (460g/l, H2O, 23℃) |
Water Solubility | 460 g/L (20 ºC) |
BRN | 1753625 |
InChIKey | NRKYWOKHZRQRJR-UHFFFAOYSA-N |
LogP | 0.725 at 23℃ and pH4.83 |
Dissociation constant | 0 at 23℃ |
CAS DataBase Reference | 354-38-1(CAS DataBase Reference) |
FDA UNII | 36MU16BYFK |
NIST Chemistry Reference | Acetamide, 2,2,2-trifluoro-(354-38-1) |
EPA Substance Registry System | Acetamide, 2,2,2-trifluoro- (354-38-1) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H302-H315-H319-H335 | |||||||||
Precautionary statements | P261-P264-P270-P301+P312-P302+P352-P305+P351+P338 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26-36-37/39 | |||||||||
RIDADR | 1759 | |||||||||
WGK Germany | 3 | |||||||||
Hazard Note | Harmful/Irritant | |||||||||
TSCA | T | |||||||||
HazardClass | 8 | |||||||||
PackingGroup | III | |||||||||
HS Code | 29241900 | |||||||||
NFPA 704 |
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Trifluoroacetamide price More Price(38)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 8.14690 | 2,2,2-Trifluoroacetamide for synthesis | 354-38-1 | 10G | $37 | 2024-03-01 | Buy |
Sigma-Aldrich | 8.14690 | 2,2,2-Trifluoroacetamide for synthesis | 354-38-1 | 50G | $128 | 2024-03-01 | Buy |
Sigma-Aldrich | 144657 | Trifluoroacetamide 97% | 354-38-1 | 25g | $42.1 | 2024-03-01 | Buy |
Sigma-Aldrich | 144657 | Trifluoroacetamide 97% | 354-38-1 | 100g | $111 | 2024-03-01 | Buy |
TCI Chemical | T0598 | Trifluoroacetamide >98.0%(GC) | 354-38-1 | 25g | $20 | 2024-03-01 | Buy |
Trifluoroacetamide Chemical Properties,Uses,Production
Chemical Properties
white to pale yellow or beige crystalline powder
Uses
2,2,2-Trifluoroacetamide used in a convenient alternative to the Gabriel synthesis of primary amines from halides by N-alkylation followed by cleavage of the readily-hydrolyzed trifluoroacetyl group and for improved N-alkylation under phase-transfer conditions allowing successive alkylation with different alkyl groups.
Application
Trifluoroacetamide was used as probe for determination of membrane potential and extra/intracellular volume of erythrocytes by fluorine-19 NMR studies.
Preparation
One-pot synthetic approach to produce trifluoroacetamide has been developed using an electrochemical method with the B12 complex as a catalyst under mild conditions, in open air at room temperature. Thirty examples of trifluoroacetamide were synthesized from 1,1,1-trichloro-2,2,2-trifluoroethane (CFC-113a) in moderate to good yields. This user-friendly strategy is compatible with a broad range of trifluoroacetamide syntheses.
10.1142/S1088424621500292
General Description
Trifluoroacetamide is a good quencher of tryptophan fluorescence.
Trifluoroacetamide Preparation Products And Raw materials
Raw materials
Preparation Products
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Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
CD Chemical Group Limited | +8615986615575 | info@codchem.com | China | 20356 | 58 |
Anhui Yiao New Material Technology Co., Ltd | +86-18033737140 +86-17354101231 | sales1@hbganmiao.com | China | 253 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-18789408387 | 1057@dideu.com | China | 3921 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12450 | 58 |
Hebei Guanlang Biotechnology Co,.LTD | +8619930503252 | daisy@crovellbio.com | China | 5828 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 16914 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21668 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9332 | 55 |
Zjartschem | +86-571 87238903 | jocelynpan@zjarts.com | CHINA | 993 | 58 |
View Lastest Price from Trifluoroacetamide manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
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2024-08-21 | Trifluoroacetamide
354-38-1
|
US $20.60 / KG | 1KG | 99% | 5000kg | Hebei Guanlang Biotechnology Co,.LTD | |
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2024-06-11 | Trifluoroacetamide
354-38-1
|
US $1.00 / KG | 1KG | 99% | 20t | Shaanxi Dideu Medichem Co. Ltd | |
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2024-06-11 | Trifluoroacetamide
354-38-1
|
US $50.00-40.00 / kg | 1kg | 99% | 100 tons | Anhui Yiao New Material Technology Co., Ltd |
-
- Trifluoroacetamide
354-38-1
- US $20.60 / KG
- 99%
- Hebei Guanlang Biotechnology Co,.LTD
-
- Trifluoroacetamide
354-38-1
- US $1.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- Trifluoroacetamide
354-38-1
- US $50.00-40.00 / kg
- 99%
- Anhui Yiao New Material Technology Co., Ltd
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