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Tiamulin fumarate

CAS No.
55297-96-6
Chemical Name:
Tiamulin fumarate
Synonyms
TIAMULIN HYDROGEN FUMARATE;Tiamuline Hydrogen Fumarate;DENAGARD;TIAMULIN FUMERATE;((2-(DIETHYLAMINO)ETHYL)THIO)ACETIC ACID 8-ESTER WITH (3AS,4R,5S,6S,8R,9R,9AR,10R)-OCTAHYDRO-5,8-DIHYDROXY-4,6,9,10-TETRAMETHYL-6-VINYL-3A,9-PROPANO-3AH-CYCLOPENTACYCLOOCTEN-1(4H)-ONE FUMARATE;sq22947;STAMULIN;81723hfu;dynamutilin;sandoz81723hfu
CBNumber:
CB0294038
Molecular Formula:
C32H51NO8S
Molecular Weight:
609.82
MDL Number:
MFCD27966802
MOL File:
55297-96-6.mol
Last updated:2024-12-04 20:40:58

Tiamulin fumarate Properties

Melting point 147-148°C
Boiling point 563℃
Flash point >110°(230°F)
storage temp. 2-8°C
solubility Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
form Solid
color White
Water Solubility Soluble in water
Merck 13,9495
InChIKey YXQXDXAHCSEVSD-IHAONTCTSA-N
SMILES C(/C(=O)O)=C\C(=O)O.C[C@H]1[C@@H]([C@](C[C@@H](OC(=O)CSCCN(CC)CC)C2([C@H](C)CCC31CCC(=O)[C@]32[H])C)(C)C=C)O |&1:9,10,11,13,27,36,r|
CAS DataBase Reference 55297-96-6(CAS DataBase Reference)
FDA UNII ION1Q02ZCX

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P501
Hazard Codes  Xn
Risk Statements  22
Safety Statements  36
RIDADR  UN2811 6.1/PG 3
WGK Germany  3
RTECS  AG9560000
HS Code  29419090
NFPA 704
0
2 0

Tiamulin fumarate price More Price(21)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR2721 Tiamulin fumarate Pharmaceutical Secondary Standard; Certified Reference Material, certified reference material, pharmaceutical secondary standard, pkg of 500?mg 55297-96-6 500MG $241 2024-03-01 Buy
Sigma-Aldrich 46959 Tiamulin fumarate VETRANAL?, analytical standard 55297-96-6 100mg $54.4 2024-03-01 Buy
Sigma-Aldrich 1667290 Tiamulin fumarate United States Pharmacopeia (USP) Reference Standard 55297-96-6 250mg $436 2024-03-01 Buy
Alfa Aesar J66020 Tiamulin fumarate 95% 55297-96-6 500mg $274 2024-03-01 Buy
Alfa Aesar J66020 Tiamulin fumarate 95% 55297-96-6 100mg $55.5 2023-06-20 Buy
Product number Packaging Price Buy
PHR2721 500MG $241 Buy
46959 100mg $54.4 Buy
1667290 250mg $436 Buy
J66020 500mg $274 Buy
J66020 100mg $55.5 Buy

Tiamulin fumarate Chemical Properties,Uses,Production

Chemical Properties

White Solid. soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide.

Uses

Tiamulin fumarate is a semisynthetic pleuromutilin antibiotic that binds to the ribosomal peptidyl transferase centre and inhibits protein synthesis. It is a derivative of Pleuromutilin with Antibacterial that targets Gram-positive bacteria as well as a few mycoplasma species.

Application

Tiamulin is a semi–synthetic analogue of pleuromutilin in which the hydroxyacetyl side chain is replaced with a larger diethylaminoethylthioacetyl moiety, providing greater hydrophobicity. The hemi-fumarate provides a stable salt with improved water solubility. Tiamulin is a potent and highly selective antibiotic active against a range of Gram positive bacteria, with no cross resistance to existing antibiotic classes due to its unique mode of action of inhibiting protein synthesis by binding to domain V of 23S rRNA.

Indications

Tiamulin fumarate is mainly used for Mycoplasma suis pneumonia, Haemophilus parasuis, infectious pleuropneumonia and dysentery caused by Treponema swine, and also for chronic respiratory tract of poultry, Mycoplasma pneumonia, infectious rhinitis, Escherichia coli, duck Infectious serositis.

Health Hazard

Inhalation may irritate (cough, short breathing, difficulty in breathing). Headache. It may cause moderate irritation, including a burning sensation, tearing, redness, or swelling. Itching. Causes serious eye irritation. Redness, itching, tears. Stinging. It may cause irritation to the digestive tract. Abdominal pain, nausea.

Mode of action

Tiamulin fumarate is a bacteriostatic antibiotic belonging to the pleuromutilin class, which inhibit protein synthesis by targeting the 50S bacterial ribosomal subunit and binding to peptidyl transferase, the enzyme responsible for forming peptide bonds between amino acids.

Tiamulin fumarate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 400)Suppliers
Supplier Tel Email Country ProdList Advantage
Masteam Bio-tech Co., Ltd.
+86-15200345168 +86-15200345168 bruce.lei@masteam.com CHINA 151 58
shandong perfect biotechnology co.ltd
+86-53169958659 +86-13153181156 sales@sdperfect.com China 294 58
Henan Suikang Pharmaceutical Co.,Ltd.
+86-18239973690 +86-18239973690 sales@suikangpharm.com China 311 58
Hebei Weibang Biotechnology Co., Ltd
+8615531157085 abby@weibangbio.com China 8810 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325 sales1@chuanghaibio.com China 5889 58
Hebei Dangtong Import and export Co LTD
+86-13910575315 +86-13910575315 admin@hbdangtong.com China 1000 58
Zibo Hangyu Biotechnology Development Co., Ltd
+86-0533-2185556 +8617865335152 Mandy@hangyubiotech.com China 10986 58
Nantong Guangyuan Chemicl Co,Ltd
+undefined17712220823 admin@guyunchem.com China 615 58
Shaanxi TNJONE Pharmaceutical Co., Ltd
+8618092446649 sarah@tnjone.com China 1143 58
Apeloa production Co.,Limited
+8619933239880 admin@apcl.com.cn China 852 58

Related articles

View Lastest Price from Tiamulin fumarate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Tiamulin Dydrogen fumarate pictures 2024-12-23 Tiamulin Dydrogen fumarate
55297-96-6
US $0.00 / kg 25kg 99% 10tons Henan Suikang Pharmaceutical Co.,Ltd.
Tiamulin fumarate pictures 2024-12-23 Tiamulin fumarate
55297-96-6
US $1000.00-700.00 / ton 1ton 99% 5000 HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Tiamulin Fumarate pictures 2024-12-23 Tiamulin Fumarate
55297-96-6
US $150.00 / kg 1kg 99% 500kg Hebei Zhuanglai Chemical Trading Co Ltd
  • Tiamulin fumarate pictures
  • Tiamulin fumarate
    55297-96-6
  • US $1000.00-700.00 / ton
  • 99%
  • HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
  • Tiamulin Fumarate pictures
  • Tiamulin Fumarate
    55297-96-6
  • US $150.00 / kg
  • 99%
  • Hebei Zhuanglai Chemical Trading Co Ltd
sq22947 ter,(e)-2-butenedioate(1:1)(salt) thiamutilinfumarate STAMULIN TIAMULIN FUMARATE TIAMULIN FUMARATE VETRANAL, 100 MG Acetic acid, 2-(diethylamino)ethylthio-, (3aS,4R,5S,6S,8R,9S,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester, (2E)-2-butenedioate (1:1) (salt) [[2-(Diethylamino)ethyl]thio]-acetic acid 6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester (E)-2-butenedioate Tiamulin Fumarate (250 mg) TiaMulin FuMarate USP USP Tiamulin hydrogen famarate TyMulina hydrogen fuMarate TiaMulin FuMarate (80%,98%) ,10-tetramethyl-1-oxo-3-alpha,9-propano-3-alpha-h-cyclopentacycloocten-8-yles 14-deoxy-14-((2-diethylaminoethyl)-mercaptoacetoxy)-mutilinhydrogenfumarate 14-desossi-14-((2-dietilaminoetil)mercapto-acetossi)mutilinidrogenofumarato 81723hfu dynamutilin sandoz81723hfu Tiamulin fumer Tiamulin Fumarate (1667290) TIANFU-CHEM CAS:55297-96-6 Tiamulin fumarate Tiamulin Hydrogen fumarateQ: What is Tiamulin Hydrogen fumarate Q: What is the CAS Number of Tiamulin Hydrogen fumarate Q: What is the storage condition of Tiamulin Hydrogen fumarate Q: What are the applications of Tiamulin Hydrogen fumarate API Tiamulin Fumarate Hydrogen CAS 55297-96-6 Raw Material 80% tiamulin hydrogen fumarate 5-hydroxy-4,6,9,10-tetramethyl-1-oxo-6-vinyldecahydro-3a Tiamulin fumarate USP/EP/BP Tiamulin hydrogen fumarate CRS (89708-74-7) tiamulin fumarate Tiamulin Fumarate Usp 5-hydroxy-4,6,9,10-tetramethyl-1-oxo-6-vinyldecahydro-3a,9-propanocyclopenta[8]annulen-8-yl 2-((2-(diethylamino)ethyl)thio)acetate but-2-enedioate Taimiomycin fumarate -hydroxy-4,6,9,10-tetramethyl-1-oxo-6-vinyldecahydro-3a,9- TIAMULIN FUMERATE TIAMULIN HYDROGEN FUMARATE DENAGARD Tiamuline Hydrogen Fumarate ((2-(DIETHYLAMINO)ETHYL)THIO)ACETIC ACID 8-ESTER WITH (3AS,4R,5S,6S,8R,9R,9AR,10R)-OCTAHYDRO-5,8-DIHYDROXY-4,6,9,10-TETRAMETHYL-6-VINYL-3A,9-PROPANO-3AH-CYCLOPENTACYCLOOCTEN-1(4H)-ONE FUMARATE Fumarate tymitin Tymectin fumarate 80%Tiamulin fumarate Tiamulin Dydrogen fumarate Yanhusuo acid Taimiaocin Tiamulin hydrogen famarate98% C17575800 Tiamulin fumerate Tylvalosin succinate 55297-96-6 5297-96-6 C28H47NO4SC4H4O4 C32H51NO8S Amines Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Sulfur & Selenium Compounds API