Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>Flavin adenine dinucleotide

Flavin adenine dinucleotide

Flavin adenine dinucleotide Structure
Flavin adenine dinucleotide structure
CAS No.
146-14-5
Chemical Name:
Flavin adenine dinucleotide
Synonyms
DISODIUM FLAVINE ADENINE DINUCLEOTIDE;Fademin;flavitan;flavinat;Flavinin;Wakadenin;NSC 112207;FAD Powder;Flavine Adenine;5'-ester with adenosine
CBNumber:
CB0294159
Molecular Formula:
C27H33N9O15P2
Molecular Weight:
785.55
MDL Number:
MFCD00041835
MOL File:
146-14-5.mol
Last updated:2024-11-25 20:05:57
Request For Quotation

Flavin adenine dinucleotide Properties

Density 2.08±0.1 g/cm3(Predicted)
storage temp. −20°C
solubility Methanol (Slightly, Heated), Water (Slightly)
pka 1.13±0.50(Predicted)
form powder
color orange
Merck 4091
Stability Stable. Incompatible with strong oxidizing agents.
InChIKey VWWQXMAJTJZDQX-ZGGJIJKNNA-N
CAS DataBase Reference 146-14-5
EWG's Food Scores 1
FDA UNII ZC44YTI8KK
EPA Substance Registry System Riboflavin 5'-(trihydrogen diphosphate), P'.fwdarw.5'-ester with adenosine (146-14-5)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P280-P302+P352-P362+P364
Safety Statements  24/25
WGK Germany  3
RTECS  AU7470000
F  8-10-21
HS Code  29349990

Flavin adenine dinucleotide price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC F532268 FlavineAdenineDinucleotide 146-14-5 25mg $1200 2021-12-16 Buy
American Custom Chemicals Corporation NUC0003041 FLAVIN ADENINE DINUCLEOTIDE 98.00% 146-14-5 25MG $408.85 2021-12-16 Buy
American Custom Chemicals Corporation NUC0003041 FLAVIN ADENINE DINUCLEOTIDE 98.00% 146-14-5 100MG $435.4 2021-12-16 Buy
American Custom Chemicals Corporation NUC0003041 FLAVIN ADENINE DINUCLEOTIDE 98.00% 146-14-5 250MG $488.5 2021-12-16 Buy
Crysdot CD70002093 Flavine-adeninedinucleotide 97% 146-14-5 5g $357 2021-12-16 Buy
Product number Packaging Price Buy
F532268 25mg $1200 Buy
NUC0003041 25MG $408.85 Buy
NUC0003041 100MG $435.4 Buy
NUC0003041 250MG $488.5 Buy
CD70002093 5g $357 Buy

Flavin adenine dinucleotide Chemical Properties,Uses,Production

Description

Flavin adenine dinucleotide (FAD) is a cofactor for cytochrome-b5 reductase, the enzyme that maintains hemoglobin in its functional reduced state, and for glutathione reductase. This enzyme also protects erythrocytes from oxidative damage. FAD is a redox cofactor of several essential reactions in metabolism. This cofactor exists in two redox states, with FAD and FADH2 being the oxidized and reduced forms, respectively. FAD is formed of a riboflavin moiety (vitamin B2) coupled to a phosphate group of an ADP molecule. The reaction starts with the conversion of riboflavin into flavin mononucleotide catalyzed by riboflavin kinase. Flavin mononucleotide is subsequently transformed into FAD by adding an AMP moiety from ATP catalyzed by FAD-synthase. Therefore, FAD availability is tightly dependent on vitamin B2 and energy metabolism[1].

References

[1] Schnekenburger, M. and M. Diederich. “Nutritional Epigenetic Regulators in the Field of Cancer: New Avenues for Chemopreventive Approaches.”Epigenetic Cancer Therapy (2015): 393-425.

Chemical Properties

solid

Uses

Labelled Flavine Adenine xidase. Riboflavin kinase tumor necrosis factor receptor 1 NADPH oxidase

Uses

The prosthetic group of certain flavoproteins including D-amino acid oxidase, glucose oxidase, glycine oxidase, fumaric hydrogenase, histaminase, and xanthine oxidase. Riboflavin kinase tumor necrosis factor receptor 1 NADPH oxidase.

Definition

An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5′-position.

Purification Methods

Small quantities of FAD are purified by paper chromatography using tert-butyl alcohol/water, cutting out the main spot and eluting with water. Larger amounts can be precipitated from water as the uranyl complex by adding a slight excess of uranyl acetate to a solution at pH 6.0, dropwise and with gentle stirring. The solution is set aside overnight in the cold, and the precipitate is centrifuged off, washed with small portions of cold EtOH, then with cold peroxide-free diethyl ether. It is dried in the dark under vacuum over P2O5 at 50-60o. The uranyl complex is suspended in water, and, after adding sufficient 0.01M NaOH to adjust the pH to 7, the precipitate of uranyl hydroxide is removed by centrifugation [Huennekens & Felton Methods Enzymol 3 954 1957]. It can also be crystallised from water. It should be kept in the dark. More recently it was purified by elution from a DEAE-cellulose (Whatman DE 23) column with 0.1M phosphate buffer pH 7, and the purity was checked by TLC. [Holt & Cotton, J Am Chem Soc 109 1841 1987, Beilstein 26 III/IV 3632.]

Flavin adenine dinucleotide Preparation Products And Raw materials

Raw materials

Preparation Products

Flavin adenine dinucleotide Suppliers

Global( 138)Suppliers
Supplier Tel Email Country ProdList Advantage
Maintain Biotech Co., Ltd.
+86-75589664337 +86-15112661142 cami@maintain-bio.com China 58 58
Hebei Weibang Biotechnology Co., Ltd 		+8615531157085 abby@weibangbio.com China 8810 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29881 58
Hubei xin bonus chemical co. LTD 		86-13657291602 linda@hubeijusheng.com CHINA 22963 58
Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
Hebei Mojin Biotechnology Co., Ltd 		+86 13288715578 +8613288715578 sales@hbmojin.com China 12841 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32165 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250 1026@dideu.com China 22783 58
Sense Chemicals (Shanghai) Co., Ltd. 		+86-21-52751036; +8613818977689 david.dai@sensechemicals.com China 225 58
Supplier Advantage
Maintain Biotech Co., Ltd.
58
Hebei Weibang Biotechnology Co., Ltd 		58
Henan Tianfu Chemical Co.,Ltd. 		55
career henan chemical co 		58
Hubei xin bonus chemical co. LTD 		58
Chongqing Chemdad Co., Ltd 		58
Hebei Mojin Biotechnology Co., Ltd 		58
TargetMol Chemicals Inc. 		58
Dideu Industries Group Limited 		58
Sense Chemicals (Shanghai) Co., Ltd. 		58

Related articles

View Lastest Price from Flavin adenine dinucleotide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
FLAVIN ADENINE DINUCLEOTIDE pictures 2024-11-25 FLAVIN ADENINE DINUCLEOTIDE
146-14-5
 US $10.00 / KG 100KG 99% 100 mt Hebei Weibang Biotechnology Co., Ltd
Flavin adenine dinucleotide pictures 2024-11-19 Flavin adenine dinucleotide
146-14-5
 US $30.00-59.00 / mg 100% 10g TargetMol Chemicals Inc.
FLAVIN ADENINE DINUCLEOTIDE pictures 2024-04-23 FLAVIN ADENINE DINUCLEOTIDE
146-14-5
 US $1.00 / KG 1KG 99.91% 200000 Ouhuang Engineering Materials (Hubei) Co., Ltd

Flavin adenine dinucleotide Spectrum

FLAVIN ADENINE DINUCLEOTIDE(146-14-5)1HNMR

146-14-5(Flavin adenine dinucleotide)Related Search:

Stannous chloride dihydrate Sulfoxaflor Nuclease Coenzyme A NAD+
Glutathione Nicotinamide Adenine Flavin adenine dinucleotide disodium salt FLAVIN ADENINE DINUCLEOTIDE
N(6)-aminohexyl-flavin adenine dinucleotide FLAVIN ADENINE DINUCLEOTIDE DISODIUM SALT N-HYDRATE,FLAVIN ADENINE DINUCLEOTIDE DISODIUM SALT DIHYDRATE,FLAVIN ADENINE DINUCLEOTIDE NA-SALT FLAVIN ADENINE DINUCLEOTIDE DISODIUM SALT HYDRATE Flavin adenine dinucleotide ammonium salt 500 MG FLAVIN ADENINE DINUCLEOTIDE.NA-SALT PURE
flavin-adenine dinucleotide phosphate FLAVIN ADENINE DINUCLEOTIDE-AGAROSE Flavin Adenine Dinucleotide, Disodium Salt (1.24544)

1of4

adenine-flavindinucleotide adenine-flavinedinucleotide adenine-riboflavindinuceotide flavitan isoalloxazine-adeninedinucleotide riboflavin5’-(trihydrogendiphosphate),5’.fwdarw.5’-esterwithadenosine riboflavin5’-(trihydrogendiphosphate),5’-5’-esterwithadenosine riboflavin-adeninedinucleotide riboflavine-adeninedinucleotide FLAVIN ADENINE DINUCLEOTIDE Flavine-adenine dinucleotide adenine-riboflavindinucleotide adenosine5’-(trihydrogenpyrophosphate),5’-5’-esterwithriboflavine flavinadenindinucleotide flavinadeninedinucleotidedisodium flavinat flavineadeninedinucleotide,disodiumflavineadeninedinucleotide flavineadenosinediphosphate FLAVIN ADENINE DINUCLEOTIDE 2NA (FAD) Riboflavine 5'-adenosine diphosphate Adenine-riboflavine dinucleotide Adenosine 5'-(trihydrogen pyrophosphate), 5'→5'-ester with riboflavine (8CI) Fademin NSC 112207 Riboflavin 5'-adenosine diphosphate Riboflavine, 5'-ester with adenosine 5'-diphosphate (8CI) FLAVINE ADENINE DINUCLEOTIDE SODIUM SALT extrapure flavin adenosine dinucleotide Riboflavin 5-(trihydrogen diphosphate), P?5-ester with adenosine Riboflavin 5'-(trihydrogen diphosphate) 5'-ester with adenosine Riboflavin5'-(trihydrogen diphosphate), P'® Flavinin Wakadenin Flavine-adenine dinucleotide,96% Flavine Adenine Flavin adenine dinucleotide ,95% Flavine Adenine Dinucleotide Sodium Salt (FAD) extrapure, 95% flavine Adenine Dinucleotide-13C5 Ammonium SaltQ: What is flavine Adenine Dinucleotide-13C5 Ammonium Salt Q: What is the CAS Number of flavine Adenine Dinucleotide-13C5 Ammonium Salt FLAVIN ADENINE DINUCLEOTIDE USP/EP/BP DISODIUM FLAVINE ADENINE DINUCLEOTIDE FAD Powder (((2R,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl)methoxy)(((((2R,3S,4S)-5-(7,8-dimethyl-2,4-dioxo-2H,3H,4H,10H-benzo[g]pteridin-10-yl)-2,3,4-trihydroxypentyl)oxy)(hydroxy)phosphoryl)oxy)phosphinic acid Flavine adenine dinucleotide,FAD Riboflavin5'-(trihydrogen diphosphate), P'?5'-ester with adenosine 146-14-5 C2213C5H31N9Na2O15P2 C27H31N9O15P2Na2 C27H33N9O15P2 C27N33N9O15P2 Metabolic Pathways Metabolomics Electron Transport and Cellular Respiration Cofactors and Substrates BioChemical Biochemistry Vitamin Derivatives Vitamins