ChemicalBook >> CAS DataBase List >>cis-5-({[1-(4-chlorophenyl)-1H-tetraazol-5-yl]sulfanyl}acetyl)-2,8-dimethyl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole

cis-5-({[1-(4-chlorophenyl)-1H-tetraazol-5-yl]sulfanyl}acetyl)-2,8-dimethyl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole

cis-5-({[1-(4-chlorophenyl)-1H-tetraazol-5-yl]sulfanyl}acetyl)-2,8-dimethyl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole structure

CAS No.: 442656-02-2

Chemical Name:: cis-5-({[1-(4-chlorophenyl)-1H-tetraazol-5-yl]sulfanyl}acetyl)-2,8-dimethyl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole

Synonyms: AG-205;AG-205 (AG205;AG-205 >=98% (HPLC);cis-5-({[1-(4-chlorophenyl)-1H-tetraazol-5-yl]sulfanyl}acetyl)-2,8-dimethyl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole;Ethanone, 2-[[1-(4-chlorophenyl)-1H-tetrazol-5-yl]thio]-1-(1,2,3,4,4a,9b-hexahydro-2,8-dimethyl-5H-pyrido[4,3-b]indol-5-yl)-;cis-2-[[1-(4-Chlorophenyl)-1H-tetrazol-5-yl]thio]-1-(1,2,3,4,4a,9b-hexahydro-2,8-dimethyl-5H-pyrido[4,3-b]indol-5-yl)-ethanone

CBNumber:: CB02985116

Molecular Formula:: C22H23ClN6OS

Molecular Weight:: 454.98

MDL Number:

MOL File:: 442656-02-2.mol

Last updated:2023-06-30 15:45:59

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cis-5-({[1-(4-chlorophenyl)-1H-tetraazol-5-yl]sulfanyl}acetyl)-2,8-dimethyl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole Properties

storage temp.	2-8°C
solubility	Soluble to 50 mM in DMSO
form	powder
color	off-white to brown
FDA UNII	02137X034H

SAFETY

Risk and Safety Statements

WGK Germany	3

cis-5-({[1-(4-chlorophenyl)-1H-tetraazol-5-yl]sulfanyl}acetyl)-2,8-dimethyl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole price More Price(5)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	A1487	AG-205 ≥98% (HPLC)	442656-02-2	5mg	$210	2024-03-01	Buy
Sigma-Aldrich	A1487	AG-205 ≥98% (HPLC)	442656-02-2	25mg	$322	2024-03-01	Buy
Tocris	6242	AG205 ≥98%(HPLC)	442656-02-2	25	$573	2021-12-16	Buy
Tocris	6242	AG205 ≥98%(HPLC)	442656-02-2	5	$147	2021-12-16	Buy
AK Scientific	SYN5581	AG-205	442656-02-2	100mg	$1660	2021-12-16	Buy

Product number	Packaging	Price	Buy
A1487	5mg	$210	Buy
A1487	25mg	$322	Buy
6242	25	$573	Buy
6242	5	$147	Buy
SYN5581	100mg	$1660	Buy

cis-5-({[1-(4-chlorophenyl)-1H-tetraazol-5-yl]sulfanyl}acetyl)-2,8-dimethyl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole Chemical Properties,Uses,Production

Uses

AG-205 has been used to investigate the neuroprotective effects of norgestrel on stressed photoreceptors. It has also been used to study the effect of blocking progesterone receptor membrane component 1 in 661W cells.

Biochem/physiol Actions

AG-205 is a Pgrmc1 (progesterone receptor membrane component 1) inhibitor. AG-205 alters the spectroscopic properties of the Pgrmc1-heme complex. AG-205 inhibits cancer cell viability and cancer cell progression. acting preferentially on Pgrmc1-expressing cells.

storage

Store at +4°C

cis-5-({[1-(4-chlorophenyl)-1H-tetraazol-5-yl]sulfanyl}acetyl)-2,8-dimethyl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole Preparation Products And Raw materials

Raw materials

Preparation Products

cis-5-({[1-(4-chlorophenyl)-1H-tetraazol-5-yl]sulfanyl}acetyl)-2,8-dimethyl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole Suppliers

Global( 7)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58
Energy Chemical	021-58432009 400-005-6266	marketing1@energy-chemical.com	China	44843	58
Changzhou Furuisi Biotechnology Co., Ltd	0519-85524369	3477467573@qq.com	China	8618	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	28118	58

Supplier	Advantage
Sigma-Aldrich	80
Shanghai Hongye Biotechnology Co. Ltd	58
Energy Chemical	58
Changzhou Furuisi Biotechnology Co., Ltd	58
TargetMol Chemicals Inc.	58

AG-205 cis-2-[[1-(4-Chlorophenyl)-1H-tetrazol-5-yl]thio]-1-(1,2,3,4,4a,9b-hexahydro-2,8-dimethyl-5H-pyrido[4,3-b]indol-5-yl)-ethanone cis-5-({[1-(4-chlorophenyl)-1H-tetraazol-5-yl]sulfanyl}acetyl)-2,8-dimethyl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole AG-205 >=98% (HPLC) Ethanone, 2-[[1-(4-chlorophenyl)-1H-tetrazol-5-yl]thio]-1-(1,2,3,4,4a,9b-hexahydro-2,8-dimethyl-5H-pyrido[4,3-b]indol-5-yl)- AG-205 (AG205 442656-02-2