Azido-PEG10-acid
- CAS No.
- 1644163-57-4
- Chemical Name:
- Azido-PEG10-acid
- Synonyms
- N3-PEG10-COOH;Azido-PEG11-acid;Azido-PEG10-acid;Azido-PEG10-tBu Ester;N3-PEG10-CH2CH2COOH/Propanoic acid, 3-[(29-azido-3,6,9,12,15,18,21,24,27-nonaoxanonacos-1-yl)oxy]-
- CBNumber:
- CB03062335
- Molecular Formula:
- C23H45N3O12
- Molecular Weight:
- 555.62
- MDL Number:
- MFCD26127811
- MOL File:
- 1644163-57-4.mol
Azido-PEG10-acid price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| BroadPharm | BP-21820 | Azido-PEG10-acid 98% | 1644163-57-4 | 100mg | $240 | 2021-12-16 | Buy |
| Apolloscientific | BIPG1111 | Azido-PEG10-acid | 1644163-57-4 | 100mg | $795 | 2021-12-16 | Buy |
| purepeg | 437710 | N3-PEG10-CH2CH2COOH min.95% | 1644163-57-4 | 250mg | $265 | 2021-12-16 | Buy |
| Acrotein | B-0903 | N3-PEG10-CH2CH2COOH 97% | 1644163-57-4 | 0.25g | $302.5 | 2021-12-16 | Buy |
Azido-PEG10-acid Chemical Properties,Uses,Production
Description
Azido-PEG10-acid is a water soluble PEG compound containing an azide group with a terminal carboxylic acid. The azide (N3) group is reactive with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Uses
Azido-PEG10-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG10-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Azido-PEG10-acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| Wuhan Borenpharm Co., Ltd | 027-65563561 18717150066 | 3207347307@qq.com | CHINA | 1238 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 +86-15680926068 | 1924344760@confluore.cn | China | 2996 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39927 | 58 |
| Alabiochem Tech.Co., Ltd. | 512-58900862 400-0707518 | sales@alabiochem.com | China | 970 | 59 |
| Hunan HuaTeng Pharmaceutical Co., Ltd., | 400-8592883 15367835770 | viola@huatengsci.com | China | 5874 | 58 |
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-0431-80514535 19917294565 | et@chemextension.com | China | 3962 | 55 |
View Lastest Price from Azido-PEG10-acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-03-24 | azido-PEG10-Acid
1644163-57-4
|
US $0.00 / g | 1g | >98.00% | 1g | Xian confluore Biological Technology Co., Ltd. |
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- azido-PEG10-Acid
1644163-57-4
- US $0.00 / g
- >98.00%
- Xian confluore Biological Technology Co., Ltd.