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ChemicalBook >> CAS DataBase List >>4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate

4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate

4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate Structure
4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate structure
CAS No.
740081-22-5
Chemical Name:
4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate
Synonyms
6-acetoxy-4-(3-chloro-2-fluoroanilino)-7-methoxyquinazoline;4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl ...;4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate;6-Quinazolinol, 4-[(3-chloro-2-fluorophenyl)amino]-7-methoxy-, 6-acetate
CBNumber:
CB03145935
Molecular Formula:
C17H13ClFN3O3
Molecular Weight:
361.75
MDL Number:
MOL File:
740081-22-5.mol
Last updated:2022-08-26 12:10:47
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4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate Properties

Boiling point 454.4±45.0 °C(Predicted)
Density 1.425±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka 5.22±0.30(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC C989238 4-((3-Chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-ylAcetate 740081-22-5 50mg $45 2021-12-16 Buy
AK Scientific 5764DN 4-((3-Chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-ylacetate 740081-22-5 1g $92 2021-12-16 Buy
Chemenu CM216563 4-((3-Chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-ylacetate 97% 740081-22-5 5g $184 2021-12-16 Buy
Alichem 740081225 4-((3-Chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-ylacetate 740081-22-5 5g $189 2021-12-16 Buy
Ambeed A143974 4-((3-Chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-ylacetate 97% 740081-22-5 25g $223 2021-12-16 Buy
Product number Packaging Price Buy
C989238 50mg $45 Buy
5764DN 1g $92 Buy
CM216563 5g $184 Buy
740081225 5g $189 Buy
A143974 25g $223 Buy

4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate Chemical Properties,Uses,Production

Description

AZD3759 is a novel epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) on the basis of gefitinib and has been proven to enter the central nervous system. Although the promising antitumor effects of AZD3759 on non-small cell lung cancer (NSCLC) have been demonstrated in clinical trials, the regulatory effects of this inhibitor on the antitumor efficacy of radiation (RA) are unclear. AZD3759 Intermediate 2 is a key intermediate in the synthesis of AZD3759.

Uses

AZD3759 Intermediate 2 can be used as a pharmaceutical intermediate.

4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate Preparation Products And Raw materials

Raw materials

Preparation Products

4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate Suppliers

Global( 43)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32715 60
career henan chemical co 		+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Shanghai Rlavie Technology Co ltd 		+86-021-67759270 +8617717059219 sales@rlavie.com China 1030 58
Hubei Ipure Biology Co., Ltd 		+8613367258412 ada@ipurechemical.com China 10326 58
CR Corporation Lomited 		fred.wen@crcorporation.cn CHINA 12069 58
Hefei TNJ Chemical Industry Co.,Ltd. 		0551-65418684 +8618949823763 sales@tnjchem.com China 25363 58
Aromsyn Co., Ltd. 		+86-0571-85585865 +8613336024896 CB@aromsyn.com China 19185 58
ZHEJIANG JIUZHOU CHEM CO., LTD 		+86-0576225566889 +86-13454675544 admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com China 19947 58
Aceschem Inc. 		+1-817863-6948 +1-（817）863-6948 sales@aceschem.com United States 19639 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131980 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Shanghai Rlavie Technology Co ltd 		58
Hubei Ipure Biology Co., Ltd 		58
CR Corporation Lomited 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
Aromsyn Co., Ltd. 		58
ZHEJIANG JIUZHOU CHEM CO., LTD 		58
Aceschem Inc. 		58
Amadis Chemical Company Limited 		58

View Lastest Price from 4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate pictures 2022-01-04 4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate
740081-22-5
 US $0.00-0.00 / KG 1g 98%min 25kgs/month Shanghai Rlavie Technology Co ltd
4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate pictures 2020-02-18 4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate
740081-22-5
 US $1.00 / KG 1KG 99% 200kgs Career Henan Chemical Co
6-acetoxy-4-(3-chloro-2-fluoroanilino)-7-methoxyquinazoline 4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate 6-Quinazolinol, 4-[(3-chloro-2-fluorophenyl)amino]-7-methoxy-, 6-acetate 4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl ... 740081-22-5