Se-Aspirin
- CAS No.
- 1850293-95-6
- Chemical Name:
- Se-Aspirin
- Synonyms
- Se-Aspirin;2-((2-Selenocyanatoethyl)carbamoyl)phenyl acetate;Selenocyanic acid, 2-[[2-(acetyloxy)benzoyl]amino]ethyl ester
- CBNumber:
- CB03152740
- Molecular Formula:
- C12H12N2O3Se
- Molecular Weight:
- 311.2
- MDL Number:
- MOL File:
- 1850293-95-6.mol
Se-Aspirin price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 19315 | Se-Aspirin ≥98% | 1850293-95-6 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 19315 | Se-Aspirin ≥98% | 1850293-95-6 | 5mg | $139 | 2024-03-01 | Buy |
| Cayman Chemical | 19315 | Se-Aspirin ≥98% | 1850293-95-6 | 10mg | $243 | 2024-03-01 | Buy |
| Cayman Chemical | 19315 | Se-Aspirin ≥98% | 1850293-95-6 | 50mg | $987 | 2024-03-01 | Buy |
| ApexBio Technology | C5667 | Se-Aspirin | 1850293-95-6 | 10mg | $277 | 2021-12-16 | Buy |
Se-Aspirin Chemical Properties,Uses,Production
Description
Se-Aspirin is a hybrid of selenium and a nonsteroidal anti-inflammatory drug that has been shown to reduce the viability of different cancer cell lines, particularly colorectal cancer (CRC) cells (IC50 = 3.4 μM). It can inhibit the cell cycle in G1 and G2/M phases and induce apoptosis by activating caspase 3/7 and PARP cleavage. Long-term exposure to Se-Aspirin is reported to cause an increase in intracellular reactive oxygen species levels in CRC cells.
Uses
Se-Aspirin is a hybrid of selenium and a nonsteroidal anti-inflammatory drug that has been shown to reduce the viability of different cancer cell lines, particularly colorectal cancer (CRC) cells (IC50 = 3.4 μM). It can inhibit the cell cycle in G1 and G2/M phases and induce apoptosis by activating caspase 3/7 and PARP cleavage. Long-term exposure to Se-Aspirin is reported to cause an increase in intracellular reactive oxygen species levels in CRC cells.[Cayman Chemical]
References
[1] plano d, karelia d n, pandey m k, et al. design, synthesis, and biological evaluation of novel selenium (se-nsaid) molecules as anticancer agents[j]. journal of medicinal chemistry, 2016, 59(5): 1946-1959.
Se-Aspirin Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
| Hubei Chuchang Biotech Co., Ltd. | +undefined15623860702 | info@chuchangbiotech.com | China | 211 | 58 |
| Zhengzhou Huiju Chemical Co., Ltd. | 0371-55900031 18137872243 | 2853979815@qq.com | China | 10006 | 55 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8140 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11974 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 19704 | 58 |
| ApexBio Technology | -- | sales@apexbt.com | United States | 6251 | 58 |
View Lastest Price from Se-Aspirin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-12 | Se-Aspirin
1850293-95-6
|
US $136.00-528.00 / mg | ≥98% | 10g | TargetMol Chemicals Inc. |
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- Se-Aspirin
1850293-95-6
- US $136.00-528.00 / mg
- ≥98%
- TargetMol Chemicals Inc.