Bromo-PEG4-Azide
- CAS No.
- 1951439-37-4
- Chemical Name:
- Bromo-PEG4-Azide
- Synonyms
- N3-PEG4-Br;Bromo-PEG4-N3;Azido-PEG4-Br;N3-PEG4-CH2CH2Br;1-azido-14-bromo-3,6,9,12-tetraoxatetradecane;N3-PEG4-CH2CH2Br/3,6,9,12-Tetraoxatetradecane, 1-azido-14-bromo-;1-azido-2-[2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethoxy]ethane - 95%
- CBNumber:
- CB03162925
- Molecular Formula:
- C10H21BrN3O4+
- Molecular Weight:
- 327.19544
- MDL Number:
- MFCD27977494
- MOL File:
- 1951439-37-4.mol
Bromo-PEG4-Azide price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| BroadPharm | BP-22128 | Bromo-PEG4-azide 98% | 1951439-37-4 | 250mg | $380 | 2021-12-16 | Buy |
| BroadPharm | BP-22128 | Bromo-PEG4-azide 98% | 1951439-37-4 | 500MG | $650 | 2021-12-16 | Buy |
| Activate Scientific | AS107849 | N3-PEG4-CH2CH2Br 97% | 1951439-37-4 | 1g | $790 | 2021-12-16 | Buy |
| BroadPharm | BP-22128 | Bromo-PEG4-azide 98% | 1951439-37-4 | 1g | $980 | 2021-12-16 | Buy |
| Acrotein | B-1431 | N3-PEG4-CH2CH2Br 97% | 1951439-37-4 | 0.25g | $247.5 | 2021-12-16 | Buy |
Bromo-PEG4-Azide Chemical Properties,Uses,Production
Description
Bromo-PEG4-azide is a bifunctional crosslinker containing a bromide and a terminal azide. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a good leaving group for nucleophilic substitution. The azide(N3) group is reactive with alkyne, BCN, DBCO via Click Chemistry.
Uses
Bromo-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Bromo-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Bromo-PEG4-Azide Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32239 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38648 | 58 | |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
| Changzhou AniKare Pharmatech Co., Ltd. | +86-0519-8359-8696 +8618018249389 | sales@anikare.com | China | 9875 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 +86-15680926068 | 1924344760@confluore.cn | China | 2996 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
View Lastest Price from Bromo-PEG4-Azide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-10-28 | Bromo-PEG4-azide
1951439-37-4
|
US $55.00-39.00 / mg | 10g | TargetMol Chemicals Inc. | |||
 |
2024-03-24 | Azido-PEG4-Br
1951439-37-4
|
US $0.00 / g | 1g | >98.00% | 1g | Xian confluore Biological Technology Co., Ltd. |
-
- Bromo-PEG4-azide
1951439-37-4
- US $55.00-39.00 / mg
- TargetMol Chemicals Inc.
-
- Azido-PEG4-Br
1951439-37-4
- US $0.00 / g
- >98.00%
- Xian confluore Biological Technology Co., Ltd.