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PHOSPHORAMIDON

PHOSPHORAMIDON structure

CAS No.: 36357-77-4

Chemical Name:: PHOSPHORAMIDON

Synonyms: eucyl)-;yptophan;PHOSPHORAMIDON;PHOSPHORAMIDON SODIUM SALT;PHOSPHORAMIDON DISODIUM SALT DIHYDRATE;N-(A-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-LEU-TRP;N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-LEU-TRP-OH;N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-LEU-TRP 2NA;N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-LEU-TRP SODIUM SALT;N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN

CBNumber:: CB0324672

Molecular Formula:: C23H34N3O10P

Molecular Weight:: 543.51

MDL Number:: MFCD00080262

MOL File:: 36357-77-4.mol

MSDS File:: SDS

Last updated:2023-04-23 13:52:06

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PHOSPHORAMIDON Properties

Density	1.48±0.1 g/cm3(Predicted)
storage temp.	−20°C
solubility	H₂O: 1 mM Stock solution stable for 1 month at –20° C.
pka	-0.66±0.50(Predicted)
FDA UNII	T3G94E2LB1

SAFETY

Risk and Safety Statements

Safety Statements	22-24/25
WGK Germany	3
F	10-21

PHOSPHORAMIDON Chemical Properties,Uses,Production

Definition

ChEBI: A dipeptide isolated from the cultures of Streptomyces tanashiensis.

Enzyme inhibitor

This glycosyl phosphoramidopeptide (FWfree-acid = 543.51 g/mol; CAS 36357-77-4), also systematically named as N-(a-rhamnopyranosyloxyhydroxyphosphinyl)- L-leucyl-L-tryptophan, is a slow-binding thermolysin inhibitor (Ki = 30 nM). Note: Phosphoramidon is an epimer of talopeptin. Stock 1 mg/mL aqueous solutions of phosphoramidon are stable for one month at –20°C. Target(s): atrolysin A; atrolysin C; bacillolysin; carboxypeptidase C, weakly inhibited; coccolysin; cytosol alanyl aminopeptidase, weakly inhibited; dactylysin; endothelin-converting enzyme; endothelin-converting enzyme 2; fungalysin; gametolysin; granzyme B; Legionella metalloendopeptidase; leucyl aminopeptidase, weakly inhibited; Listeria metalloprotease Mpl; lysine carboxypeptidase, or lysine(arginine) carboxypeptidase; carboxypeptidase N; mycolysin; neprilysin, or enkephalinase, Ki = 0.8 nM; oligopeptidase O; peptidyl-dipeptidase A, or angiotensin I-converting enzyme; pitrilysin, or protease Pi; pseudolysin, or Pseudomonas aeruginosa elastase; pyruvate decarboxylase; thermolysin (27,28,41,43- 53); urethanase; vibriolysin; and Xaa-Pro aminopeptidase, or aminopeptidase P.

PHOSPHORAMIDON Preparation Products And Raw materials

Raw materials

Preparation Products

PHOSPHORAMIDON Suppliers

Global( 35)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Alpha Biopharmaceuticals Co., Ltd	+86-15542445688	sales@alabiochem.com	China	888	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32165	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52924	58
Wuhan Fortuna Chemical Co.,Ltd	+8618007136271	hk@fortunachem.com	China	5998	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15839	69
Alabiochem Tech.Co., Ltd.	0512-58900862 400-0707518	sales@alabiochem.com	China	997	59
Sichuan Kulinan Technology Co., Ltd	400-1166-196 18981987031	cdhxsj@163.com	China	11707	57
Codow Chemical Co.,Ltd.	18620099427	amy@howeipharm.com	China	17687	55
Shandong Xiya Chemical Co., Ltd.	4009903999 13395398332	sales@xiyashiji.com	China	20806	60
Alabiotech Inc.	001-619-354-5251	sales@alabiotech-e.com	United States	972	60

Supplier	Advantage
Alpha Biopharmaceuticals Co., Ltd	58
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
Wuhan Fortuna Chemical Co.,Ltd	58
3B Pharmachem (Wuhan) International Co.,Ltd.	69
Alabiochem Tech.Co., Ltd.	59
Sichuan Kulinan Technology Co., Ltd	57
Codow Chemical Co.,Ltd.	55
Shandong Xiya Chemical Co., Ltd.	60
Alabiotech Inc.	60

36357-77-4(PHOSPHORAMIDON)Related Search:

PHOSPHORAMIDON--N/H PHOSPHORAMIDON SODIUM SALT, FROM MICROBIAL SOURCE,PHOSPHORAMIDON PHOSPHORAMIDON NA 2H20 GLYCYL-L-TRYPTOPHAN L-ALANYL-L-TRYPTOPHAN

PHOSPHORAMIDON H-LEU-TRP-OH

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N-(A-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-LEU-TRP N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-LEU-TRP 2NA N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-LEU-TRP-OH N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-LEU-TRP SODIUM SALT N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN, 2NA N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXY-PHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN DISODIUM SALT N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN DISODIUM SALT DIHYDRATE N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN (SODIUM SALT) N-(ALPHA-RHAMNOPYRANOSYLPHOSPHONO)-L-LEUCYL-L-TRYPTOPHAN DISODIUM SALT N-[N-[[(6-deoxy-alpha-L-mannopyranosyl)oxy]hydroxyphosphinyl]-L-leucyl]-L-tryptophan N-[N-[(6-Deoxy-α-L-mannopyranosyloxy)hydroxyphosphinyl]-L-Leu-]-L-Trp-OH L-Tryptophan,N-[[(6-deoxy-a-L-mannopyranosyl)oxy]hydroxyphosphinyl]-L-leucyl- eucyl)- l-tryptophan,n-(n-(((6-deoxy-alpha-l-mannopyranosyl)oxy)hydroxyphosphinyl)-l-l n-(n-(((6-deoxy-alpha-l-mannopyranosyl)oxy)hydroxyphosphinyl)-l-leucyl)-l-tr yptophan PHOSPHORAMIDON PHOSPHORAMIDON DISODIUM SALT DIHYDRATE PHOSPHORAMIDON SODIUM SALT L-Tryptophan, N-[[(6-deoxy-α-L-mannopyranosyl)oxy]hydroxyphosphinyl]-L-leucyl- 36357-77-4 BioChemical Biochemicals and Reagents Enzymes, Inhibitors, and Substrates Enzyme Inhibitors by Type Enzyme Inhibitors by Enzyme Enzyme Inhibitors P to Q Phosphodiesterase 3',5'-Cyclic Nucleotide Substrate Analogs peptides Pepetides