Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol

1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol

1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol Structure
1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol structure
CAS No.
1394121-05-1
Chemical Name:
1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol
Synonyms
181525;GNE-2861;GNE-2861; GNE 2861; GNE2861.;p21 activated kinases,inhibit,Inhibitor,PAK,GNE 2861,GNE-2861,GNE2861;1-[2-[3-(2-aminopyrimidin-4-yl)-2-(2-methoxyethylamino)benzimidazol-5-yl]ethynyl]cyclohexan-1-ol;1-[2-[1-(2-Amino-4-pyrimidinyl)-2-[(2-methoxyethyl)amino]-1H-benzimidazol-6-yl]ethynyl]cyclohexanol;1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol;Cyclohexanol, 1-[2-[1-(2-amino-4-pyrimidinyl)-2-[(2-methoxyethyl)amino]-1H-benzimidazol-6-yl]ethynyl]-
CBNumber:
CB03380132
Molecular Formula:
C22H26N6O2
Molecular Weight:
406.48
MDL Number:
MOL File:
1394121-05-1.mol
Last updated:2024-07-02 08:54:58
Request For Quotation

1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol Properties

storage temp. Store at -20°C
solubility DMSO:82.83(Max Conc. mg/mL);203.77(Max Conc. mM)
Ethanol:40.65(Max Conc. mg/mL);100.0(Max Conc. mM)
form A solid
color White to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P321-P304+P340-P305+P351+P338-P332+P313-P362+P364-P337+P313-P403+P233-P405-P501
NFPA 704
0
2 0

1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 29458 GNE-2861 1394121-05-1 5mg $303 2024-03-01 Buy
Tocris 6490 GNE2861 ≥98%(HPLC) 1394121-05-1 5 $214 2021-12-16 Buy
ChemScene CS-0012111 GNE2861 99.47% 1394121-05-1 25mg $300 2021-12-16 Buy
ChemScene CS-0012111 GNE2861 99.47% 1394121-05-1 5mg $90 2021-12-16 Buy
ChemScene CS-0012111 GNE2861 99.47% 1394121-05-1 10mg $150 2021-12-16 Buy
Product number Packaging Price Buy
29458 5mg $303 Buy
6490 5 $214 Buy
CS-0012111 25mg $300 Buy
CS-0012111 5mg $90 Buy
CS-0012111 10mg $150 Buy

1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol Chemical Properties,Uses,Production

Biological Activity

GNE 2861 is a PAK inhibitor with selectivity for group II. It inhibits PAK4, PAK5 and PAK6 with IC50 values of 7.5, 36 and 126 nM, respectively.

in vitro

GNE-2861 is compound 4 from the reference.

target

IC50: 7.5 nM (PAK4), 36 nM (PAK5), 126 nM (PAK6)

storage

Store at -20°C

1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol Preparation Products And Raw materials

Raw materials

Preparation Products

1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol Suppliers

Global( 26)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525 masar@topule.com China 8474 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 57511 58
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. 17702719238 17702719238 sales@sun-shinechem.com China 950 64
ChemShuttle, Inc. 0510-83588313-802 18800520310; sales@chemshuttle.com China 3000 62
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4287 55
BOC Sciences 16314854226 info@bocsci.com United States 9926 65
ATK CHEMICAL COMPANY LIMITED 3429815786 13301662590 sales@atkchemical.com China 10420 55
Jiaxing Deyi Chemical Co., Ltd. 0573-86-0573-85866609 13325730825 945717149@qq.com China 8035 58
Wuhan Sun-shine Bio-technology Corporation Limited +86-027-6552-2453 sales@sun-shinechem.com China 727 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Wuhan Topule Biopharmaceutical Co., Ltd 		58
Aladdin Scientific 		58
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. 64
ChemShuttle, Inc. 62
Shanghai Lollane Biological Technology Co.,Ltd. 55
BOC Sciences 65
ATK CHEMICAL COMPANY LIMITED 55
Jiaxing Deyi Chemical Co., Ltd. 58
Wuhan Sun-shine Bio-technology Corporation Limited 58
1-[2-[3-(2-aminopyrimidin-4-yl)-2-(2-methoxyethylamino)benzimidazol-5-yl]ethynyl]cyclohexan-1-ol 1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol GNE-2861; GNE 2861; GNE2861. 1-[2-[1-(2-Amino-4-pyrimidinyl)-2-[(2-methoxyethyl)amino]-1H-benzimidazol-6-yl]ethynyl]cyclohexanol 181525 GNE-2861 Cyclohexanol, 1-[2-[1-(2-amino-4-pyrimidinyl)-2-[(2-methoxyethyl)amino]-1H-benzimidazol-6-yl]ethynyl]- p21 activated kinases,inhibit,Inhibitor,PAK,GNE 2861,GNE-2861,GNE2861 1394121-05-1 APIS