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FEXOFENADINE HYDROCHLORIDE

FEXOFENADINE HYDROCHLORIDE Structure
FEXOFENADINE HYDROCHLORIDE structure
CAS No.
138452-21-8
Chemical Name:
FEXOFENADINE HYDROCHLORIDE
Synonyms
Fexofendine Hcl;FEXOFENADINE HCL;Fexofenadine Hydrochloride (200 mg);terfenidine carboxylate hydrochloride;CARBOXYTERFENADINE,TERFENADINECARBOXYLATE;Fexofenadine hydrochloride, 10 mM in DMSO;Fexofenadine Hydrochloride (200 mg)F1E2890.996mg/mg(ai);2-[4-[1-hydroxy-4-[4-[hydroxy(diphenyl)methyl]-1-piperidinyl]butyl]phenyl]-2-methylpropanoic acid;2-[4-[1-hydroxy-4-[4-(hydroxy-diphenyl-methyl)-1-piperidyl]-butyl]phenyl]-2-methyl-propanoic acid hydrochloride;(+)-4-(1-HYDROXY-4-(4-HYDROXYDIPHENYLMETHYL)1-PIPERIDINYL)-BUTYL)a,a-(DIMETHYL BENZENE ACETIC ACID HYDROCHLORIDE
CBNumber:
CB0340913
Molecular Formula:
C32H40ClNO4
Molecular Weight:
538.12
MDL Number:
MFCD00865710
MOL File:
138452-21-8.mol
Last updated:2024-11-19 23:02:33
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FEXOFENADINE HYDROCHLORIDE Properties

storage temp. −20°C
solubility DMSO: 32 mg/mL, soluble
form solid
color white

SAFETY

Risk and Safety Statements

WGK Germany  3

FEXOFENADINE HYDROCHLORIDE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Medical Isotopes, Inc. 10243 Fexofenadine HCl 138452-21-8 100mg $850 2021-12-16 Buy
Product number Packaging Price Buy
10243 100mg $850 Buy

FEXOFENADINE HYDROCHLORIDE Chemical Properties,Uses,Production

Description

The metabolite of seldane (terfenadine), fexofenadine, was launched in the USA. A histamine H1 receptor antagonist, fexofenadine is more effect than its parent compound without the associated side-effects.

Originator

Sepracor (USA)

Uses

Fexofenadine HCl (Allegra) is a selective, specific H1 antagonist that is structurally related to the butyrophenone tranquilizer haloperidol. It is the active carboxylic acid metabolite of terfenadine (no longer commercially available in the United States). It binds mainly to the peripheral H1 receptors, with minimal crossing of the blood–brain barrier and hence minimal sedative effects. Fexofenadine lacks the cardiotoxic effects of its parent drug, terfenadine. However, it has been associated with increased QT interval, syncope, and ventricular arrhythmia in at least one susceptible patient with preexisting cardiovascular risk. To date, no significant interactions have been demonstrated with fexofenadine when administered concomitantly with azole antifungals or macrolide antibiotics. Indicated for seasonal allergic rhinitis and chronic idiopathic urticaria.

Uses

Anti-histamine

Definition

ChEBI: Fexofenadine hydrochloride is a diarylmethane.

brand name

Allegra

Dosage forms

60 mg PO b.i.d.

FEXOFENADINE HYDROCHLORIDE synthesis

154477-55-1
138452-21-8
Synthesis of FEXOFENADINE HYDROCHLORIDE from Methyl-4-4(4-hydroxy diphenyl-methyl)-piperidine-1-oxobutyl-2-2-dimethyl phenyl

FEXOFENADINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Fexofenadine

Preparation Products

FEXOFENADINE HYDROCHLORIDE Suppliers

Global( 69)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6312 58
sgtlifesciences pvt ltd 		+8617013299288 dj@sgtlifesciences.com China 12373 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418684 +8618949823763 sales@tnjchem.com China 25356 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38631 58
Suzhou ARTK Medchem Co., Ltd. 		+86-512-68323658 +86-18168183658 sales1@artkmedchem.com China 39004 58
XIAMEN AMITY INDUSTRY AND TRADE CO., LTD. 		+8618950047208 ellena@amitychem.com China 43416 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15839 69
XiaoGan ShenYuan ChemPharm co,ltd 15527768850 1791901229@qq.com China 8835 52
Supplier Advantage
TargetMol Chemicals Inc. 		58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		58
sgtlifesciences pvt ltd 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
TargetMol Chemicals Inc. 		58
Suzhou ARTK Medchem Co., Ltd. 		58
XIAMEN AMITY INDUSTRY AND TRADE CO., LTD. 		58
Amadis Chemical Company Limited 		58
3B Pharmachem (Wuhan) International Co.,Ltd. 69
XiaoGan ShenYuan ChemPharm co,ltd 52

View Lastest Price from FEXOFENADINE HYDROCHLORIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Fexofenadine hydrochloride pictures 2024-11-19 Fexofenadine hydrochloride
138452-21-8
 US $43.00-107.00 / mg 100% 10g TargetMol Chemicals Inc.
Fexofenadine hydrochloride pictures 2024-11-19 Fexofenadine hydrochloride
138452-21-8
 US $43.00-107.00 / mg 100% 10g TargetMol Chemicals Inc.

138452-21-8(FEXOFENADINE HYDROCHLORIDE)Related Search:

FEXOFENADINE HYDROCHLORIDE Terfenadine alpha,alpha-Diphenyl-4-piperidinomethanol Diphenylpiperidin-4-ylmethanol hydrochloride Fexofenadine hydrochloride
Acetic acid Fexofenadine 2-Phenylisobutyric acid THIOGLYCOLIC ACID N-BUTYL ESTER 4-(PHENYLMETHYL)-PIPERIDINE HYDROCHLORIDE
(2RS)-2-(4-BUTYLPHENYL)PROPANOIC ACID Benzeneacetic acid, 4-butyl--alpha--methyl-, (-alpha-S)- (9CI) 4-N-BUTYLPHENETHYL ALCOHOL 4-(TERT-BUTYL)-ALPHA-METHYLBENZYL ALCOHOL (2RS)-2-(4-N-PROPYLPHENYL)PROPANOIC ACID
4-(diphenylmethyl)piperidine 2-(4-PIPERIDYL)-2-PROPANOL PHENYL-PIPERIDIN-4-YL-METHANOL

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terfenidine carboxylate hydrochloride ALPHA,ALPHA-DIMETHYL-4-[1-HYDROXY-4-[4-(HYDROXYDIPHENYLMETHYL)-1-PIPERIDINYL]BUTYL]-BENZENEACETIC ACID HYDROCHLORIDE 2-[4-[1-hydroxy-4-[4-(hydroxy-diphenyl-methyl)-1-piperidyl]-butyl]phenyl]-2-methyl-propanoic acid hydrochloride FEXOFENADINE HCL CARBOXYTERFENADINE,TERFENADINECARBOXYLATE Fexofendine Hcl (+)-4-(1-HYDROXY-4-(4-HYDROXYDIPHENYLMETHYL)1-PIPERIDINYL)-BUTYL)a,a-(DIMETHYL BENZENE ACETIC ACID HYDROCHLORIDE Fexofenadine Hydrochloride (200 mg) Fexofenadine Hydrochloride (200 mg)F1E2890.996mg/mg(ai) Benzeneacetic acid, 4-[1-hydroxy-4-[4-(hydroxydiphenylMethyl)-1-piperidinyl]butyl]-α,α-diMethyl-, hydrochloride (1:1) 2-[4-[1-hydroxy-4-[4-[hydroxy(diphenyl)methyl]-1-piperidinyl]butyl]phenyl]-2-methylpropanoic acid Fexofenadine hydrochloride, 10 mM in DMSO 138452-21-8 C32H39NO4.HCl