L-xylose
- CAS No.
- 609-06-3
- Chemical Name:
- L-xylose
- Synonyms
- XYLOSE;L-(-)-XYLOSE;(2S,3R,4S)-2,3,4,5-Tetrahydroxypentanal;L-XYL;L-XYLOSE;XYLOSE, L;L-Xylose,99%;laevo-xylose;L-Xylose (9CI);L(-)XYLOSE 99%
- CBNumber:
- CB0357344
- Molecular Formula:
- C5H10O5
- Molecular Weight:
- 150.13
- MDL Number:
- MFCD00151096
- MOL File:
- 609-06-3.mol
Melting point | 150-152 °C(lit.) |
---|---|
Boiling point | 191.65°C (rough estimate) |
Density | 1.525 |
refractive index | -20 ° (C=10, H2O) |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | H2O: 0.1 g/mL, clear, colorless |
pka | 12.46±0.20(Predicted) |
form | Crystalline Powder |
color | White to off-white |
optical activity | [α]24/D 18.7°, c = 4 in H2O |
Water Solubility | within almost transparency |
Sensitive | Hygroscopic |
BRN | 1723080 |
InChIKey | SRBFZHDQGSBBOR-VVZXFQNISA-N |
LogP | -2.390 (est) |
CAS DataBase Reference | 609-06-3(CAS DataBase Reference) |
FDA UNII | A4JW0V2MYA |
EPA Substance Registry System | L-Xylose (609-06-3) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P305+P351+P338 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 24/25-36-26 | |||||||||
WGK Germany | 3 | |||||||||
F | 3-10 | |||||||||
TSCA | Yes | |||||||||
HS Code | 29400000 | |||||||||
NFPA 704 |
|
L-xylose price More Price(33)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 851590 | L-(?)-Xylose, mixture of anomers ≥99% | 609-06-3 | 5g | $29.94 | 2024-03-01 | Buy |
Sigma-Aldrich | 851590 | L-(?)-Xylose, mixture of anomers ≥99% | 609-06-3 | 25g | $56.6 | 2024-03-01 | Buy |
TCI Chemical | X0021 | L-(-)-Xylose >97.0%(T) | 609-06-3 | 5g | $67 | 2024-03-01 | Buy |
TCI Chemical | X0021 | L-(-)-Xylose >97.0%(T) | 609-06-3 | 25g | $267 | 2024-03-01 | Buy |
Alfa Aesar | B21622 | L-(-)-Xylose, 99% | 609-06-3 | 5g | $46.65 | 2024-03-01 | Buy |
L-xylose Chemical Properties,Uses,Production
Chemical Properties
L-Xylose is a white fine crystalline powder. It is an aldopentose that has a molecular formula C5H10O5 and a molar mass of 150.13 g/mol. The structure of L-xylose is presented in Figure 1. The optical rotations of D- and L-xylose are α20D = -18.6° and α20D = +18.6°, respectively (Fischer and Ruff, 1900). L-Xylose can exist in open chain form, as a pyranose or as a furanose. The relative concentrations of different stereoisomers have not been specified for L-xylose. However, for D-xylose the distribution of different forms in water are: 36.5% α-pyranose, 6% β-pyranose and less than 1 % in open chain and furanose form (Pastinen, 2000). Most likely L-xylose acts similarly to its enantiomer, and thus pyranose rings are predominant.
Figure 1. Structure of L-xylose A) as a Fischer projection, B) as a ball and stick model in acyclic form and C) as a ball and stick model in pyranose ring form.
Uses
L-Xylose is used in the synthesis of L-Xylose derivatives as selective sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes.
Definition
ChEBI: Aldehydo-L-xylose is a xylose of ring-opened form having L-configuration.
Application
l-Xylose is a suitable starting material for the production of L-ribonucleosides. L- Xylose can be converted into an L-ribose derivative via oxidation and reduction steps. This product is then glycosylated to give L-ribonucleosides: L-uridine, L-cytidine, L- adenosine and L-guanosine (Moyroud and Strazewski, 1999; Chelain et al., 1995).
L-Xylose can also be used as a starting material for the production of polyhydroxypyrrolidines and related analogues. These compounds have many biological activities. They are shown to have anti-HIV effects, inhibit tumor growth, and also act as ?- and ?-glucosidase inhibitors, which is of relevance for the development of diabetes drugs (Behr and Guillerm, 2007).
Preparation
L-Xylose can be produced from L-xylulose by isomerization. This can be achieved either enzymatically or chemically under alkaline conditions. The equilibrium of the reaction between D-xylose and D-xylulose in an aqueous solution has been determined at pH 6.8-7.4 and at 25 °C to be 85:15 in favor of D-xylose (Tewari et al., 1985).
L-xylose Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Beijing Ribio Biotech Co.,Ltd | 010-62664360 +8613328773880 | wucy@ribio.com.cn | China | 117 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12839 | 58 |
Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18775 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
Hangzhou FandaChem Co.,Ltd. | +8615858145714 | FandaChem@Gmail.com | China | 9206 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29881 | 58 |
Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 17453 | 58 |
Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8618959220845 | sales@amoychem.com | China | 6383 | 58 |
View Lastest Price from L-xylose manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-11-27 | L-xylose
609-06-3
|
US $0.00 / KG | 1KG | 98.0% | 500kg/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
2024-10-22 | L-xylose
609-06-3
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | ||
2024-05-20 | L-XYLOSE
609-06-3
|
US $0.00-0.00 / kg | 1kg | 98.0%min | 10tons/year | AstaTech(Chengdu) Biopharmaceutical Corp. |
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