3-Aminobenzeneboronic acid hemisulfate salt
- CAS No.
- 66472-86-4
- Chemical Name:
- 3-Aminobenzeneboronic acid hemisulfate salt
- Synonyms
- 3-AMINOPHENYLBORONIC ACID HEMISULFATE;M-APBA;SKL266;3-Aminobenzeneboroni;boronic acid hemisuL;M-AMINOPHENYLBORIC ACID HEMISULFATE;(3-aminophenyl)-boronic aci sulfate;aminophenylboronic acid hemisulfate;3-aminophenylboric acid hemisulphate;M-AMINOPHENYLBORONIC ACID HEMISULFATE
- CBNumber:
- CB0357728
- Molecular Formula:
- C12H18B2N2O8S
- Molecular Weight:
- 371.96692
- MDL Number:
- MFCD00013111
- MOL File:
- 66472-86-4.mol
- MSDS File:
- SDS
| Melting point | ≥300 °C |
|---|---|
| storage temp. | Inert atmosphere,2-8°C |
| Water Solubility | Soluble in water |
| form | Crystalline Powder |
| color | White to slightly beige |
| Sensitive | Hygroscopic |
| BRN | 8094151 |
| InChIKey | XMVGYYBQCXVVHU-UHFFFAOYSA-N |
| CAS DataBase Reference | 66472-86-4 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 3-10 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29310095 | |||||||||
| NFPA 704 |
|
3-Aminobenzeneboronic acid hemisulfate salt price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A71751 | 3-Aminophenylboronic acid hemisulfate salt ≥95% | 66472-86-4 | 5g | $136 | 2024-03-01 | Buy |
| Sigma-Aldrich | A71751 | 3-Aminophenylboronic acid hemisulfate salt ≥95% | 66472-86-4 | 25g | $440 | 2024-03-01 | Buy |
| TCI Chemical | A1774 | 3-Aminophenylboronic Acid Hemisulfate | 66472-86-4 | 1g | $31 | 2024-03-01 | Buy |
| TCI Chemical | A1774 | 3-Aminophenylboronic Acid Hemisulfate | 66472-86-4 | 5g | $94 | 2024-03-01 | Buy |
| Alfa Aesar | A17240 | 3-Aminobenzeneboronic acid hemisulfate, 98+% | 66472-86-4 | 1g | $33.65 | 2024-03-01 | Buy |
3-Aminobenzeneboronic acid hemisulfate salt Chemical Properties,Uses,Production
Chemical Properties
White to slightly beige crystalline powder
Uses
3-Aminobenzeneboronic acid hemisulfate salt is a boronic acid derivative, which can be used as an intermediate in pharmaceutical synthesis. Adsorbent additive for the chromatographic separation of 3'-terminal polynucleotides from RNA.
Application
3-Aminophenylboronic acid hemisulfate salt is used in the synthesis of:
Phenylboronic acid-functionalized inverse opal hydrogels within microfluidic flow cells for glucose sensing.
Phenylboronic acid-salicylhydroxamic acid-derived complexing reagent for protein immobilization on chromatographic support.
It can also be used in the preparation of phenylboronic acid (PBA) monolayer-modified Au electrode for the voltammetric sensing of uridine and cytidine.
Preparation
3-Aminobenzeneboronic acid hemisulfate salt synthesis: Benzenamine, 3-bromo-N-(diphenylmethylene)- (80,0 g; 0.24 moles) was added to the cryogenic reactor along with 1.4 equivalents of triisopropyl borate and dissolved in tetrahydrofuran. The resulting solution was cooled to -80°C under an inert atmosphere and 1.35 equivalents of n-butyllithium (as a solution in n-hexane) was added maintaining the internal temperature. When complete conversion was achieved, the reaction mixture was added to a dilute mixture of sulfuric acid (1 M) and toluene. The layers were separated to obtain an aqueous solution of 3-aminophenylboronic acid hydrogen sulfate (assay yield: 85%). 3-Aminobenzeneboronic acid hemisulfate salt can be obtained by precipitating a 0.5 M aqueous solution at pH 7.2 (pH corrected with 33% aqueous NaOH) at a temperature of 0-5°C. Filtration and drying under vacuum at 40°C for 8 hours yielded 21.7 g of 3-Aminobenzeneboronic acid hemisulfate salt (0.16 moles; 66% molar yield).
3-Aminobenzeneboronic acid hemisulfate salt Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32957 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29882 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 | 1022@dideu.com | China | 3882 | 58 |
View Lastest Price from 3-Aminobenzeneboronic acid hemisulfate salt manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-09-12 | 3-Aminobenzeneboronic acid hemisulfate salt
66472-86-4
|
US $0.00-0.00 / KG | 1KG | 98% | 1ton | Henan Aochuang Chemical Co.,Ltd. | |
 |
2021-11-26 | 3-Aminophenylboronic Acid Hemisulfate
66472-86-4
|
US $10.00 / Kg/Bag | 1Kg/Bag | 99% | 20 Tons | Hebei Zhanyao Biotechnology Co. Ltd | |
 |
2020-04-27 | 3-Aminobenzeneboronic acid hemisulfate salt
66472-86-4
|
US $0.10 / KG | 1KG | 99.0% | 1000 tons | Shaanxi Dideu Medichem Co. Ltd |
-
- 3-Aminobenzeneboronic acid hemisulfate salt
66472-86-4
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 3-Aminophenylboronic Acid Hemisulfate
66472-86-4
- US $10.00 / Kg/Bag
- 99%
- Hebei Zhanyao Biotechnology Co. Ltd
-
- 3-Aminobenzeneboronic acid hemisulfate salt
66472-86-4
- US $0.10 / KG
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
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