2-Chloro-6-methylaniline
- CAS No.
- 87-63-8
- Chemical Name:
- 2-Chloro-6-methylaniline
- Synonyms
- 6-CHLORO-O-TOLUIDINE;6-CHLORO-2-METHYLANILINE;6COT;NSC 60121;oro-6-methyL;TIMTEC-BB SBB004153;6-chloro-o-toluidin;2-Chloro-6-methylani;6-CHLORO-2-TOLUIDINE;6-ChIoro-o-toluidine
- CBNumber:
- CB0361613
- Molecular Formula:
- C7H8ClN
- Molecular Weight:
- 141.6
- MDL Number:
- MFCD00007679
- MOL File:
- 87-63-8.mol
Melting point | 10-12 °C(lit.) |
---|---|
Boiling point | 215 °C(lit.) |
Density | 1.152 g/mL at 25 °C(lit.) |
refractive index |
n |
Flash point | 210 °F |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
form | Oil |
pka | 2.51±0.10(Predicted) |
color | Clear Colourless to Pale Purple |
Water Solubility | Immiscible |
BRN | 774624 |
InChIKey | WFNLHDJJZSJARK-UHFFFAOYSA-N |
CAS DataBase Reference | 87-63-8(CAS DataBase Reference) |
EWG's Food Scores | 1 |
FDA UNII | 76F11RQ7TB |
NIST Chemistry Reference | Benzenamine, 2-chloro-6-methyl-(87-63-8) |
EPA Substance Registry System | 6-Chloro-2-methylaniline (87-63-8) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() ![]() ![]() GHS06,GHS08,GHS09 |
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Signal word | Danger | |||||||||
Hazard statements | H301+H311+H331-H341-H373-H410 | |||||||||
Precautionary statements | P201-P273-P280-P301+P310+P330-P302+P352+P312-P304+P340+P311 | |||||||||
Hazard Codes | Xi,Xn | |||||||||
Risk Statements | 36/37/38-20/21/22 | |||||||||
Safety Statements | 26-36-36/37/39 | |||||||||
RIDADR | UN 3429 6.1/PG 3 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | XU5100000 | |||||||||
TSCA | Yes | |||||||||
HazardClass | 6.1 | |||||||||
PackingGroup | III | |||||||||
HS Code | 29214300 | |||||||||
NFPA 704 |
|
2-Chloro-6-methylaniline price More Price(38)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | C51008 | 2-Chloro-6-methylaniline 98% | 87-63-8 | 1g | $35.4 | 2023-01-07 | Buy |
TCI Chemical | A1959 | 2-Chloro-6-methylaniline >98.0%(GC)(T) | 87-63-8 | 5g | $70 | 2024-03-01 | Buy |
TCI Chemical | A1959 | 2-Chloro-6-methylaniline >98.0%(GC)(T) | 87-63-8 | 25g | $205 | 2024-03-01 | Buy |
Alfa Aesar | L02629 | 2-Chloro-6-methylaniline, 98% | 87-63-8 | 25g | $315.65 | 2024-03-01 | Buy |
Alfa Aesar | L02629 | 2-Chloro-6-methylaniline, 98% | 87-63-8 | 1g | $37.1 | 2021-12-16 | Buy |
2-Chloro-6-methylaniline Chemical Properties,Uses,Production
Description
2-chloro-6-methylaniline is an important organic synthesis intermediate widely applied to chemical pharmacy, pesticides, and organic synthesis. In the aspects of chemical pharmacy and pesticides, 2-chloro-6-methylaniline can be used as a reaction starting material to participate in the preparation processes of tyrosine kinase inhibitors dasatinib, indazole derivatives with anti-breast cancer activity, 2-methyl-6-chlorophenyl sulfonylurea derivatives with bacteriostatic activity and the like; in the aspect of organic synthesis, 2-chloro-6-methylaniline can introduce chemical groups such as hydrazine, nitro, cyano, halogen (F, Cl, Br), and the like into an aromatic ring through diazotization reaction, thereby participating in wide chemical reactions.
Chemical Properties
clear yellow to red-brown liquid
Chemical Properties
The chloromethylanilines are colorless or white crystalline solids or liquids, some have a mild fishy odor.
Uses
2-Chloro-6-methylaniline is a substituted aniline used in the preparation of various pharmaceutical compounds. 2-Chloro-6-methylaniline showed inhibition of the polymerization of vinyl acetate.
Preparation
A preparation method of 2-chloro-6-methylaniline takes 3-chloro-5-methyl-4-nitroaniline as a starting material, water as a solvent, and sulfuric acid as a reactant. Eliminates amino groups through diazotization reaction, reduces by hypophosphorous acid to obtain an intermediate, and finally takes iron powder as reducing nitro groups to prepare the 2-chloro-6-methylaniline through a one-pot reaction.
Potential Exposure
Most of the isomers are used in dyestuff manufacture. The 3-chloro-para isomer is used to kill birds. It is marketed as pelleted bait for control of bird populations.
Shipping
UN2239 Chlorotoluidines, solid, Hazard Class: 6.1; Labels: 6.1-Poisonous materials. UN3429 Chlorotoluidines, liquid, Hazard Class: 6.1; Labels: 6.1- Poisonous materials
Incompatibilities
Incompatible with oxidizers, strong acids; chloroformates, and acid anhydrides, isocyanates, aldehydes forming fire and explosive hazards.
2-Chloro-6-methylaniline Preparation Products And Raw materials
Raw materials
Preparation Products
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Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
China Synchem Technology Co.,Ltd. | +86-0552-4929304 +86-18055277008 | wangxuhui1985@126.com | China | 57 | 55 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20294 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21668 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32760 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29894 | 58 |
Shanghai Arbor Chemical Co., Ltd. | 021-60451682 | act@arborchemical.com | CHINA | 906 | 58 |
Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | sales@dolonchem.com | CHINA | 2972 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
View Lastest Price from 2-Chloro-6-methylaniline manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2024-01-02 | 2-Chloro-6-methylaniline
87-63-8
|
US $50.00-1.00 / KG | 1KG | 99 | g-kg-tons,free sample is available | Henan Fengda Chemical Co., Ltd | |
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2022-10-01 | 2-Chloro-6-methylaniline
87-63-8
|
US $0.00-0.00 / KG | 1KG | 98% | 1ton | Henan Aochuang Chemical Co.,Ltd. | |
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2022-02-19 | 2-Chloro-6-methylaniline
87-63-8
|
US $0.00 / KG | 1KG | 98.3% | 100 tons | Honest Joy Holdings Limited
|
-
- 2-Chloro-6-methylaniline
87-63-8
- US $50.00-1.00 / KG
- 99
- Henan Fengda Chemical Co., Ltd
-
- 2-Chloro-6-methylaniline
87-63-8
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 2-Chloro-6-methylaniline
87-63-8
- US $0.00 / KG
- 98.3%
- Honest Joy Holdings Limited
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