ChemicalBook >> CAS DataBase List >>4-amino-5-ethylsulfonyl-2-methoxy-N-[[1-(1,1,2,2,2-pentadeuterioethyl)pyrrolidin-2-yl]methyl]benzamide

4-amino-5-ethylsulfonyl-2-methoxy-N-[[1-(1,1,2,2,2-pentadeuterioethyl)pyrrolidin-2-yl]methyl]benzamide

CAS No.
1216626-17-3
Chemical Name:
4-amino-5-ethylsulfonyl-2-methoxy-N-[[1-(1,1,2,2,2-pentadeuterioethyl)pyrrolidin-2-yl]methyl]benzamide
Synonyms
[2H5]-Amisulpride;Guaiacol Impurity 28;Amisulpride Impurity 27;4-amino-5-ethylsulfonyl-2-methoxy-N-[[1-(1,1,2,2,2-pentadeuterioethyl)pyrrolidin-2-yl]methyl]benzamide;Amisulpride Hydrochloride D5Q: What is Amisulpride Hydrochloride D5 Q: What is the CAS Number of Amisulpride Hydrochloride D5 Q: What is the storage condition of Amisulpride Hydrochloride D5 Q: What are the applications of Amisulpride Hydrochloride D5
CBNumber:
CB03677791
Molecular Formula:
C17H22D5N3O4S
Molecular Weight:
374.50978889
MDL Number:
MOL File:
1216626-17-3.mol
Last updated:2024-07-02 08:54:58

4-amino-5-ethylsulfonyl-2-methoxy-N-[[1-(1,1,2,2,2-pentadeuterioethyl)pyrrolidin-2-yl]methyl]benzamide Properties

storage temp. Store at -20°C
solubility Chloroform: slightly soluble,Methanol: slightly soluble
form A solid
color White to off-white
Stability Hygroscopic

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
NFPA 704
0
2 0

4-amino-5-ethylsulfonyl-2-methoxy-N-[[1-(1,1,2,2,2-pentadeuterioethyl)pyrrolidin-2-yl]methyl]benzamide price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 30075 Amisulpride-d5 1216626-17-3 1mg $287 2024-03-01 Buy
TRC A633252 Amisulpride-d5 1216626-17-3 10mg $1695 2021-12-16 Buy
AK Scientific 8546DF Amisulpride-d5 1216626-17-3 1mg $403 2021-12-16 Buy
Product number Packaging Price Buy
30075 1mg $287 Buy
A633252 10mg $1695 Buy
8546DF 1mg $403 Buy

4-amino-5-ethylsulfonyl-2-methoxy-N-[[1-(1,1,2,2,2-pentadeuterioethyl)pyrrolidin-2-yl]methyl]benzamide Chemical Properties,Uses,Production

Description

Amisulpride-d5 is intended for use as an internal standard for the quantification of amisulpride by GC- or LC-MS. Amisulpride is a dopamine D2 and D3 receptor antagonist (Kis = 3 and 3.5 nM, respectively). It is also an antagonist of the serotonin (5-HT) receptor subtypes 5-HT2B, 5-HT7, and 5-HT7A (Kis = 13, 11.5, and 135.5 nM, respectively). It is selective for these receptors over a panel of 39 additional receptors, ion channels, and transporters (Kis = >1,000 nM for all). Amisulpride increases 7-OH-DPAT-induced decreases in dopamine and acetylcholine release in electrically stimulated rat striatal slices (EC50s = 2.2 and 1.2 nM, respectively). It increases the levels of dopamine and the dopamine metabolite 3,4-dihydroxyphenylacetic acid (DOPAC) in rat striatum and nucleus accumbens when administered intraperitoneally at a dose of 10 mg/kg. Amisulpride decreases immobility time in the forced swim test in rats, as well as reduces stress-induced decreases in sucrose consumption in a rat model of depression induced by chronic mild stress.

Uses

Labelled Amisulpride (A633250). Amisulpride is a neuroleptic agent, an analogue of Sulpiride (S689145). Amisulpride is used as an antipsychotic. Amisulpride is a dopamine receptor antagonist.

4-amino-5-ethylsulfonyl-2-methoxy-N-[[1-(1,1,2,2,2-pentadeuterioethyl)pyrrolidin-2-yl]methyl]benzamide Preparation Products And Raw materials

Raw materials

Preparation Products

4-amino-5-ethylsulfonyl-2-methoxy-N-[[1-(1,1,2,2,2-pentadeuterioethyl)pyrrolidin-2-yl]methyl]benzamide Suppliers

Global( 27)Suppliers
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Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 57511 58
Nanjing XiZe Biotechnology CO., Ltd. 025-58362220 15250997978 1511893459@qq.com China 7774 55
Artis Biotech Co. Ltd. 19138486554 18582380095 sales@artisbio.com China 2754 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9707 58
Hubei Yangxin Medical Technology Co., Ltd. 15374522761 3003392093@qq.com China 8256 55
Tianjin shijia biomedical technology co., LTD 15022261580 tjshj1212@163.com China 2417 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
ShangHai Anpel Co, Ltd. 18501792038; 18501792038 shanpel@anpel.com.cn China 9614 58
SHENZHEN PHYSTANDARD BIO-TECH CO.,LTD 0755-0755-0755-83725350 13380397412 3001280422@qq.com China 10077 58
Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 44843 58
[2H5]-Amisulpride Amisulpride Impurity 27 Amisulpride Hydrochloride D5Q: What is Amisulpride Hydrochloride D5 Q: What is the CAS Number of Amisulpride Hydrochloride D5 Q: What is the storage condition of Amisulpride Hydrochloride D5 Q: What are the applications of Amisulpride Hydrochloride D5 4-amino-5-ethylsulfonyl-2-methoxy-N-[[1-(1,1,2,2,2-pentadeuterioethyl)pyrrolidin-2-yl]methyl]benzamide Guaiacol Impurity 28 1216626-17-3