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2-(6-oxo-2-(pyridin-3-yl)-1,6-dihydropyrimidin-5-yl)acetic acid

2-(6-oxo-2-(pyridin-3-yl)-1,6-dihydropyrimidin-5-yl)acetic acid structure

CAS No.: 1210360-87-4

Chemical Name:: 2-(6-oxo-2-(pyridin-3-yl)-1,6-dihydropyrimidin-5-yl)acetic acid

Synonyms: CAY10781;2-(6-oxo-2-pyridin-3-yl-1H-pyrimidin-5-yl)acetic acid;6-Oxo-2-(3-pyridinyl)-1,6-dihydro-5-pyrimidinyl]acetic acid;5-Pyrimidineacetic acid, 3,4-dihydro-4-oxo-2-(3-pyridinyl)-;2-(6-oxo-2-(pyridin-3-yl)-1,6-dihydropyrimidin-5-yl)acetic acid

CBNumber:: CB03988596

Molecular Formula:: C11H9N3O3

Molecular Weight:: 231.21

MDL Number:: MFCD17430309

MOL File:: 1210360-87-4.mol

Last updated:2024-11-13 11:39:26

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2-(6-oxo-2-(pyridin-3-yl)-1,6-dihydropyrimidin-5-yl)acetic acid Properties

storage temp.	-20°C
solubility	DMF: insol,DMSO: 10 mg/ml,Ethanol: insol,PBS (pH 7.2): insol
form	A solid

2-(6-oxo-2-(pyridin-3-yl)-1,6-dihydropyrimidin-5-yl)acetic acid price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
aablocks	AA00JB5Y	[6-Oxo-2-(3-pyridinyl)-1,6-dihydro-5-pyrimidinyl]aceticacid	1210360-87-4	500mg	$529	2021-12-16	Buy
aablocks	AA00JB5Y	[6-Oxo-2-(3-pyridinyl)-1,6-dihydro-5-pyrimidinyl]aceticacid	1210360-87-4	1g	$857	2021-12-16	Buy
aablocks	AA00JB5Y	[6-Oxo-2-(3-pyridinyl)-1,6-dihydro-5-pyrimidinyl]aceticacid	1210360-87-4	5g	$2057	2021-12-16	Buy
aablocks	AA00JB5Y	[6-Oxo-2-(3-pyridinyl)-1,6-dihydro-5-pyrimidinyl]aceticacid	1210360-87-4	10g	$3248	2021-12-16	Buy

Product number	Packaging	Price	Buy
AA00JB5Y	500mg	$529	Buy
AA00JB5Y	1g	$857	Buy
AA00JB5Y	5g	$2057	Buy
AA00JB5Y	10g	$3248	Buy

2-(6-oxo-2-(pyridin-3-yl)-1,6-dihydropyrimidin-5-yl)acetic acid Chemical Properties,Uses,Production

Biological Activity

CAY10781 is an inhibitor of the protein-protein interaction between neuropilin-1 (NRP-1) and VEGF-A.1 It inhibits the interaction by 43% when used at a concentration of 12.5 μM. CAY10781 also inhibits VEGF-A-induced phosphorylation of VEGFR2 in catecholamine A-differentiated (CAD) cells when used at the same concentration.

References

1.Perez-Miller, S., Patek, M., Moutal, A., et al.In silico identification and validation of inhibitors of the interaction between neuropilin receptor 1 and SARS-CoV-2 Spike proteinbioRxiv308783(2020)

2-(6-oxo-2-(pyridin-3-yl)-1,6-dihydropyrimidin-5-yl)acetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

2-(6-oxo-2-(pyridin-3-yl)-1,6-dihydropyrimidin-5-yl)acetic acid Suppliers

Global( 8)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
TargetMol Chemicals Inc.		support@targetmol.com	United States	38631	58
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9806	58
DC Chemicals	021-58447131 13564518121	sales@dcchemicals.com	China	9409	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	19704	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
TargetMol Chemicals Inc.	58
Shanghai EFE Biological Technology Co., Ltd.	58
DC Chemicals	58
TargetMol Chemicals Inc.	58

View Lastest Price from 2-(6-oxo-2-(pyridin-3-yl)-1,6-dihydropyrimidin-5-yl)acetic acid manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-11-12	CAY10781 1210360-87-4	US $35.00-74.00 / mg		98.69%	10g	TargetMol Chemicals Inc.

CAY10781
1210360-87-4
US $35.00-74.00 / mg
98.69%
TargetMol Chemicals Inc.

2-(6-oxo-2-(pyridin-3-yl)-1,6-dihydropyrimidin-5-yl)acetic acid Spectrum

2-(6-oxo-2-(pyridin-3-yl)-1,6-dihydropyrimidin-5-yl)acetic acid(1210360-87-4)¹HNMR

2-(6-oxo-2-(pyridin-3-yl)-1,6-dihydropyrimidin-5-yl)acetic acid 5-Pyrimidineacetic acid, 3,4-dihydro-4-oxo-2-(3-pyridinyl)- CAY10781 6-Oxo-2-(3-pyridinyl)-1,6-dihydro-5-pyrimidinyl]acetic acid 2-(6-oxo-2-pyridin-3-yl-1H-pyrimidin-5-yl)acetic acid 1210360-87-4