Aluminon
- CAS No.
- 569-58-4
- Chemical Name:
- Aluminon
- Synonyms
- ATA;AURINTRICARBOXYLIC ACID AMMONIUM SALT;AURINTRICARBOXYLIC ACID AMMONIUM SALT, A CS;lysofon;ALUMINON;CI 43810;alactone;ALUMINONE;AluminoneGr;CI NO 43810
- CBNumber:
- CB0413969
- Molecular Formula:
- C22H17NO9
- Molecular Weight:
- 439.38
- MDL Number:
- MFCD00040925
- MOL File:
- 569-58-4.mol
- MSDS File:
- SDS
| Melting point | 220-225 °C (dec.)(lit.) |
|---|---|
| Boiling point | 573.92°C (rough estimate) |
| Density | 1.4414 (rough estimate) |
| refractive index | 1.6300 (estimate) |
| storage temp. | room temp |
| solubility | DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 10 mg/ml,PBS (pH 7.2): 100 μg/ml |
| Colour Index | 43810 |
| form | powder |
| color | Deep red |
| PH | 5.3 (10g/l, H2O, 20°C) |
| Water Solubility | 800 g/L (20 ºC) |
| Merck | 14,322 |
| BRN | 3900820 |
| Stability | Stable. |
| CAS DataBase Reference | 569-58-4 |
| FDA UNII | 23J05NR06D |
| EPA Substance Registry System | Benzoic acid, 5-[(3-carboxy-4-hydroxyphenyl)(3-carboxy-4-oxo-2,5-cyclohexadien-1-ylidene)methyl]-2-hydroxy-, triammonium salt (569-58-4) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P280a-P305+P351+P338-P321-P332+P313-P337+P313-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/38-36/37/38 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | GU4800000 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29189090 | |||||||||
| Toxicity | LD50 orally in Rabbit: 9000 mg/kg | |||||||||
| NFPA 704 |
|
Aluminon price More Price(39)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A36883 | Aurintricarboxylic acid ammonium salt ACS reagent | 569-58-4 | 25g | $71.8 | 2024-03-01 | Buy |
| Sigma-Aldrich | A0885 | Aurintricarboxylic acid ammonium salt powder | 569-58-4 | 25g | $94 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1.00128 | Aurin tricarboxylic acid ammonium salt GR for analysis (reagent for aluminium) ACS | 569-58-4 | 10g | $842 | 2024-03-01 | Buy |
| TCI Chemical | A0240 | Aluminon (mixture of isomers) | 569-58-4 | 5g | $70 | 2024-03-01 | Buy |
| TCI Chemical | A0240 | Aluminon (mixture of isomers) | 569-58-4 | 25g | $279 | 2024-03-01 | Buy |
Aluminon Chemical Properties,Uses,Production
Chemical Properties
dark red crystalline powder
Uses
It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases, Shc proteins, phosphatidylinositide 3-kinase and phospholipase C in PC12 cells. Aurintricarboxylic acid inhibits apoptosis in many cell types.
Uses
Aluminon can used as a reagent for aluminum in solution. It is also Forms brilliantly colored lakes with aluminum, chromium, iron, beryllium. Generally used for the detection and colorimetric estimation of aluminum in water, foods, tissues. Cf. Scherrer, Mogerman, J. Res. Natl. Bur. Stand. 21, 105 (1938).
Definition
ChEBI: An ammonium salt that is the ammonium salt of 3,3'-[(3-carboxy-4-oxocyclohexa-2,5-dien-1-ylidene)methylene]bis(6-hydroxybenzoic acid). A dye commonly used to detect the presence of the aluminium ion in an aqueous solution.
Biochem/physiol Actions
Aurintricarboxylic acid readily polymerizes in aqueous solution, forming a stable free radical that inhibits protein-nucleic acid interactions. It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases, Shc proteins, phosphatidylinositide 3-kinase and phospholipase C in PC12 cells. Aurintricarboxylic acid inhibits apoptosis in many cell types. Its neuroprotective effect, perhaps due to its ability to prevent down-regulation of Ca2+ impermeable GluR2 receptors or to its ability to inhibit calpain, a Ca2+-activated protease that is activated during apoptosis.
Safety Profile
Human reproductive effects by ingestion: changes in male fertility. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NH3 and NOx,.
Aluminon Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shandong Deshang Chemical Co., Ltd. | +86-0531-8875-2665 +8613153039501 | info@deshangchem.com | China | 660 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29886 | 58 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2930 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
| Shenyang Simchoice Chemical Co.,Ltd | +86-024-23769576 +86-15040101888 | sales@simchoicechem.com | China | 254 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
| Tangshan Moneide Trading Co., Ltd. | +86-315-8309571 +8615633399667 | sales@moneidechem.com | China | 574 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34553 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
View Lastest Price from Aluminon manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-10-23 | Aluminon
569-58-4
|
US $10.00-7.00 / kg | 1kg | 99.99% | 10 tons | Shandong Deshang Chemical Co., Ltd. | |
 |
2021-08-12 | Aluminon
569-58-4
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2019-07-06 | Aluminon
569-58-4
|
US $1.00 / KG | 1G | 99% | 100KG | Career Henan Chemical Co |