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C18 L-threo Ceramide (d18:1/18:0)

C18 L-threo Ceramide (d18:1/18:0) Structure
C18 L-threo Ceramide (d18:1/18:0) structure
CAS No.
95037-06-2
Chemical Name:
C18 L-threo Ceramide (d18:1/18:0)
Synonyms
Octadecanoyl-L-threo-sphingosine;C18 L-threo Ceramide (d18:1/18:0);N-[(1S,2S,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-octadecanamide;Octadecanamide, N-[(1S,2S,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-
CBNumber:
CB04665911
Molecular Formula:
C36H71NO3
Molecular Weight:
565.95
MDL Number:
MOL File:
95037-06-2.mol
Last updated:2023-05-21 10:59:17
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C18 L-threo Ceramide (d18:1/18:0) Properties

Boiling point 694.5±55.0 °C(Predicted)
Density 0.915±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
form A solid
pka 13.54±0.20(Predicted)

C18 L-threo Ceramide (d18:1/18:0) price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 24399 C18 L-threo Ceramide (d18:1/18:0) ≥98% 95037-06-2 1mg $209 2024-03-01 Buy
AK Scientific 6402EC N-[(E,2S,3S)-1,3-Dihydroxyoctadec-4-en-2-yl]octadecanamide 95037-06-2 1mg $525 2021-12-16 Buy
Product number Packaging Price Buy
24399 1mg $209 Buy
6402EC 1mg $525 Buy

C18 L-threo Ceramide (d18:1/18:0) Chemical Properties,Uses,Production

Description

C18 L-threo Ceramide is a synthetic ceramide and stereoisomer of C18 ceramide that has been used for structural characterization of natural sphingolipids.1 It inhibits rat brain mitochondrial ceramidase (mt-CDase) with an IC50 value of 8.8 μM.2

References

1. Sarmientos, F., Schwarzmann, G., and Sandhoff, K. Direct evidence by carbon-13 NMR spectroscopy for the erythro configuration of the sphingoid moiety in Gaucher cerebroside and other natural sphingolipids Eur. J. Biochem. 146(1),59-64(1985).
2. Usta, J., El Bawab, S., Roddy, P., et al. Structural requirements of ceramide and sphingosine based inhibitors of mitochondrial ceramidase Biochemistry 40(32),9657-9668(2001).

C18 L-threo Ceramide (d18:1/18:0) Preparation Products And Raw materials

Raw materials

Preparation Products

C18 L-threo Ceramide (d18:1/18:0) Suppliers

Global( 8)Suppliers
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Alfa Chemistry 		Info@alfa-chemistry.com United States 24072 58
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Supplier Advantage
Alfa Chemistry 		58
Yichang Zhongyitai Trading Co., Ltd. 58
Alfa Chemistry 60
BOC Sciences 65
Shanghai EFE Biological Technology Co., Ltd. 58
Shanghai Hongye Biotechnology Co. Ltd 58
SHANGHAI ZZBIO CO., LTD. 58
C18 L-threo Ceramide (d18:1/18:0) Octadecanoyl-L-threo-sphingosine Octadecanamide, N-[(1S,2S,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]- N-[(1S,2S,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-octadecanamide 95037-06-2