Alloc-Val-Ala-OH
- CAS No.
- 330970-70-2
- Chemical Name:
- Alloc-Val-Ala-OH
- Synonyms
- Alloc-Val-Ala-OH;((Allyloxy)carbonyl)-L-valyl-L-alanine;L-Alanine, N-[(2-propen-1-yloxy)carbonyl]-L-valyl-;(S)-2-((S)-2-(Allyloxycarbonylamino)-3-methylbutanamido)propanoic acid;(2S)-2-[(2S)-3-methyl-2-{[(prop-2-en-1-yloxy)carbonyl]amino}butanamido]propanoic acid
- CBNumber:
- CB04804398
- Molecular Formula:
- C12H20N2O5
- Molecular Weight:
- 272.3
- MDL Number:
- MOL File:
- 330970-70-2.mol
Alloc-Val-Ala-OH price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | A549735 | N-Alloc-L-valyl-L-alanine | 330970-70-2 | 500mg | $305 | 2021-12-16 | Buy |
| TRC | A549735 | N-Alloc-L-valyl-L-alanine | 330970-70-2 | 1g | $550 | 2021-12-16 | Buy |
| TRC | A549735 | N-Alloc-L-valyl-L-alanine | 330970-70-2 | 5g | $2310 | 2021-12-16 | Buy |
| TRC | A549735 | N-Alloc-L-valyl-L-alanine | 330970-70-2 | 10g | $4180 | 2021-12-16 | Buy |
| Matrix Scientific | 179881 | L-Alanine N-[(2-propen-1-yloxy)carbonyl]-L-valyl-95% | 330970-70-2 | 1g | $1486 | 2021-12-16 | Buy |
Alloc-Val-Ala-OH Chemical Properties,Uses,Production
Description
Alloc-Val-Ala-OH is a peptide linker with a terminal carboxylic acid group and an Alloc protecting group. The peptide chain can act as a cleavable linker in drug design, such as in antibody drug conjugates (ADC). The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Alloc group is stable to treatment with piperidine and TFA, and can be removed in neutral conditions with catalytic amounts of Pd(PPh3)4 in the presence of PhSiH3. This allows the allyl system to work orthogonality with the most common protecting groups.
Uses
N-Alloc-L-valyl-L-alanine is a building block in the synthesis of Tesirine, a clinical antibody-drug conjugate pyrrolobenzodiazepine dimer payload.
Alloc-Val-Ala-OH Preparation Products And Raw materials
Raw materials
Preparation Products
Alloc-Val-Ala-OH Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1803 | 55 |
| GL Biochem (Shanghai) Ltd. | +86-021-61263370 +86-18901917034 | CHINA | 3904 | 58 | |
| GL Biochem(Binhai) Ltd. | +86-021-61263370 +8615301650015 | wuqiuyan@glschina.com | China | 2975 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18137 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 +86-15680926068 | 1924344760@confluore.cn | China | 2996 | 58 |
| Hebei Fengmu Trading Co., Ltd. | +8613393234347 | Lyla@fengmuchem.com | China | 2943 | 58 |
| xinguokeji | 13120711461 | 363372932@qq.com | China | 495 | 58 |
View Lastest Price from Alloc-Val-Ala-OH manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-03-29 | Alloc-Val-Ala-OH
330970-70-2
|
US $0.00 / g | 25g | >95.00% | 25g | Xian confluore Biological Technology Co., Ltd. |
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- Alloc-Val-Ala-OH
330970-70-2
- US $0.00 / g
- >95.00%
- Xian confluore Biological Technology Co., Ltd.