felodipine-d5
- CAS No.
- 1242281-38-4
- Chemical Name:
- felodipine-d5
- Synonyms
- rac Felodipine (Ethoxy-d5);Felodipine D5Q: What is Felodipine D5 Q: What is the CAS Number of Felodipine D5 Q: What is the storage condition of Felodipine D5 Q: What are the applications of Felodipine D5
- CBNumber:
- CB04849214
- Molecular Formula:
- C18H19Cl2NO4
- Molecular Weight:
- 384.25
- MDL Number:
- MOL File:
- 1242281-38-4.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| NFPA 704 |
|
felodipine-d5 price More Price(1)
felodipine-d5 Chemical Properties,Uses,Production
Description
(±)-Felodipine-d5 is intended for use as an internal standard for the quantification of (±)-felodipine by GC- or LC-MS. (±)-Felodipine is an inhibitor of L-type calcium channels. It induces relaxation of precontracted isolated porcine coronary artery segments (EC50 = 0.15 nM), which highly express L-type calcium channels. (±)-Felodipine is selective for L-type calcium channels over N-, R-, and P/Q-type channels at 10 μM, as well as the T-type Cav3.2 channel (IC50 = 6.8 μM). (±)-Felodipine preferentially inhibits L-type calcium channels in isolated rat portal vein over rat left ventricle (IC50s = 33.9 and 3,981 nM, respectively). It decreases mean arterial blood pressure and total peripheral resistance in a rabbit model of hypertension induced by renal artery ligation when administered intravenously at doses of 30 and 100 nmol/kg.
Uses
Felodipine-d5 is the labeled analogue of Felodipine (F232375), a dihydropyridine calcium channel blocker.
felodipine-d5 Preparation Products And Raw materials
Raw materials
Preparation Products
felodipine-d5 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ChemStrong Scientific Co.,Ltd | 0755-0755-66853366 13670046396 | sales@chem-strong.com | China | 18021 | 56 |
| Shanghai Kewel Chemical Co., Ltd. | 021-64609169 18901607656 | greensnown@163.com | China | 9911 | 50 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9806 | 58 |
| Shenzhen Botel Biotechnology Co. Ltd. | 0755-22202135 13316968096 | 1979313431@qq.com | China | 8734 | 58 |
| Hefei Molake Biotechnology Co., Ltd. | 0551-66336380 18956014586 | 983438788@qq.com | China | 2118 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Shanghai YuZn Pharm. Technology Co.,Ltd. | 15921286451; 15921286451 | 2010681527@qq.com | China | 5079 | 58 |
| LGC Science (Shanghai) Ltd. | 17717235263 | cindy.yang@lgcgroup.com | China | 11677 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 17301488900 | judy.xia@synzest.com | China | 12582 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 15850508050 | rose.shi@synzest.com | China | 6210 | 58 |