(2-pyridyldithio)-PEG4-alcohol
- CAS No.
- 851961-99-4
- Chemical Name:
- (2-pyridyldithio)-PEG4-alcohol
- Synonyms
- (2-pyridyldithio)-PEG4-alcohol;Ethanol, 2-[2-[2-[2-(2-pyridinyldithio)ethoxy]ethoxy]ethoxy]-;2-(2-(2-(2-(pyridin-2-yldisulfaneyl)ethoxy)ethoxy)ethoxy)ethan-1-ol
- CBNumber:
- CB04849380
- Molecular Formula:
- C13H21NO4S2
- Molecular Weight:
- 319.44
- MDL Number:
- MFCD31561123
- MOL File:
- 851961-99-4.mol
(2-pyridyldithio)-PEG4-alcohol Chemical Properties,Uses,Production
Description
(2-pyridyldithio)-PEG2-alcohol is a PEG linker which contains a pyridyl disulfide moiety and an alcohol group. The pyridyl disulfide group can react with thiol groups of proteins over a wide range of pH level. The hydroxyl group allows for further derivatization of the compound. The hydrophilic PEG linker increases the water solubility of the compound.
Uses
(2-Pyridyldithio)-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
(2-pyridyldithio)-PEG4-alcohol Preparation Products And Raw materials
Raw materials
Preparation Products
(2-pyridyldithio)-PEG4-alcohol Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38630 | 58 | |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 +86-15680926068 | 1924344760@confluore.cn | China | 2996 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4838 | 58 |
| Changzhou Kechem Bio-Scientific Co., LTD. | 0519-68985668 13685222090 | sales@kechem.cn | China | 26028 | 58 |
| Shanghai Haohong Pharmaceutical Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 55017 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85563444 18351873721 | purchase@synzest.com | China | 10434 | 58 |
| Hangzhou Taorui Biotechnology Co., Ltd | 4000-360-990 15268198094 | sales@torreybio.com | China | 3300 | 58 |
View Lastest Price from (2-pyridyldithio)-PEG4-alcohol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-10-28 | (2-Pyridyldithio)-PEG4-alcohol
851961-99-4
|
US $50.00-72.00 / mg | 10g | TargetMol Chemicals Inc. | |||
 |
2024-03-21 | (2-pyridyldithio)-PEG4-alcohol
851961-99-4
|
US $0.00 / mg | 50mg | >99.00% | 50mg | Xian confluore Biological Technology Co., Ltd. |
-
- (2-Pyridyldithio)-PEG4-alcohol
851961-99-4
- US $50.00-72.00 / mg
- TargetMol Chemicals Inc.
-
- (2-pyridyldithio)-PEG4-alcohol
851961-99-4
- US $0.00 / mg
- >99.00%
- Xian confluore Biological Technology Co., Ltd.