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Palbociclib-025

Palbociclib-025 structure

CAS No.: 2174002-16-3

Chemical Name:: Palbociclib-025

Synonyms: N-Formyl Palbociclib;Palbociclib E;Palbociclib Impurity 025;1-Piperazinecarboxaldehyde, 4-[6-[(6-acetyl-8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-;4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carbaldehyde? (Palbociclib Impurity）;Palbociclib impurity 27/Palbociclib N-Formyl Impurity/4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carbaldehyde

CBNumber:: CB04883289

Molecular Formula:: C25H29N7O3

Molecular Weight:: 475.54

MDL Number:

MOL File:: 2174002-16-3.mol

Last updated:2023-05-15 10:43:35

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Palbociclib-025 Properties

Boiling point	765.3±70.0 °C(Predicted)
Density	1.389±0.06 g/cm3(Predicted)
solubility	Chloroform (Slightly), DMSO (Slightly)
pka	5.24±0.10(Predicted)
form	Solid
color	Light Yellow to Very Dark Yellow
FDA UNII	NJB3FNK33C

Palbociclib-025 Chemical Properties,Uses,Production

Uses

Palbociclib N-Aldehyde is an intermediate in synthesizing Palbociclib N-b-D-Glucuronide Sodium Salt (P139910), a derivative of Palbociclib (P139900) which is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.

Palbociclib-025 Preparation Products And Raw materials

Raw materials

Preparation Products

Palbociclib-025 Suppliers

Global( 41)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14332	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Hangzhou Huarong Pharm Co., Ltd.	571-86758373 +8613588754946	sales@huarongpharm.com	CHINA	3148	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11922	58
Beijing HwrkChemical Technology Co., Ltd	010-89508211 18501085097	sales.bj@hwrkchemical.com	China	8418	55
Daicel Chiral Technologies (China)CO.,LTD	021-50460086-9 15921403865	han_yajun@dctc.daicel.com	China	7191	65
Beijing Comparison Pharmaceutical Technology Co., Ltd	010-010-52878169 15801002657	sales@bjcomparison.com	China	4991	58
Wuxi Zhongkun Biochemical Technology Co., Ltd.	0510-85629785 18013409632	sales@reading-chemicals.com	China	15178	58
Shanghai Kewel Chemical Co., Ltd.	021-64609169 18901607656	greensnown@163.com	China	9906	50
Nanjing XiZe Biotechnology CO., Ltd.	025-66023220 0086-15250997978	1511893459@qq.com	China	7850	55

Supplier	Advantage
Standardpharm Co. Ltd.	58
BOC Sciences	58
Hangzhou Huarong Pharm Co., Ltd.	58
China National Standard Pharmaceutical Corporation Limited	58
Beijing HwrkChemical Technology Co., Ltd	55
Daicel Chiral Technologies (China)CO.,LTD	65
Beijing Comparison Pharmaceutical Technology Co., Ltd	58
Wuxi Zhongkun Biochemical Technology Co., Ltd.	58
Shanghai Kewel Chemical Co., Ltd.	50
Nanjing XiZe Biotechnology CO., Ltd.	55

2174002-16-3(Palbociclib-025)Related Search:

4-[6-[(8-Cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino]pyridin-3-yl]piperazine-1-carboxylic acid tert-butyl ester Palbociclib Impurity N-Oxide 4-[6-[(8-cyclopentyl-6-ethenyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinecarboxylic acid tert-butyl ester 4-[6-(6-BROMO-8-CYCLOPENTYL-5-METHYL-7-OXO-7,8-DIHYDRO-PYRIDO[2,3-D]PYRIMIDIN-2-YLAMINO)-PYRIDIN-3-YL]-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER Palbociclib Impurity 87

8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-6-vinylpyrido[2,3-d]pyrimidin-7(8H)-one Pyrido[2,3-d]pyriMidin-7(8H)-one, 8-cyclopentyl-5-Methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]aMino]- tert-butyl 4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-acetyl-8-cyclopentyl-2-[[5-(4-hydroxy-1-piperazinyl)-2-pyridinyl]amino]-5-methyl- 6-bromo-8-cyclopentyl-5-methyl-Pyrido[2,3-d]pyrimidine-2,7(1H,8H)-dione

Palbociclib Impurity 91 Palbociclib Impurity I 6-broMo-8-cyclopentyl-5-Methyl-2-(5-(piperazin-1-yl)pyridin-2-ylaMino)pyrido[2,3-d]pyriMidin-7(8H)-one Palbociclib Impurity 37 rac-trans-4-Desfluoro-4-methoxy Paroxetine Hydrochloride

Paroxetine Impurity 4 Paroxetine HCl Hemihydrate EP Impurity C HCl

1of4

Palbociclib impurity 27/Palbociclib N-Formyl Impurity/4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carbaldehyde 1-Piperazinecarboxaldehyde, 4-[6-[(6-acetyl-8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]- Palbociclib E Palbociclib Impurity 025 4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carbaldehyde? (Palbociclib Impurity） N-Formyl Palbociclib 2174002-16-3