ChemicalBook >> CAS DataBase List >>10,11-DIHYDRO-10-HYDROXYCARBAZEPINE

10,11-DIHYDRO-10-HYDROXYCARBAZEPINE

CAS No.
29331-92-8
Chemical Name:
10,11-DIHYDRO-10-HYDROXYCARBAZEPINE
Synonyms
GP 47779;BIA 2-005;GP 47779-d3;BIA 2-005-d3;Licarbazepine;Hydroxycarbamazepine;Licarbazepine Racemate;10,11-Dihydro-10-hydroxy;LICARBAZEPINE SEE 16178912;Oxcarbazepine Hydroxy Impurity
CBNumber:
CB0500702
Molecular Formula:
C15H14N2O2
Molecular Weight:
254.28
MDL Number:
MFCD00871817
MOL File:
29331-92-8.mol
MSDS File:
SDS
Last updated:2024-07-02 08:54:58

10,11-DIHYDRO-10-HYDROXYCARBAZEPINE Properties

Melting point 186-189°C
Boiling point 431.3±55.0 °C(Predicted)
Density 1.336
Flash point 2℃
storage temp. -20°C
solubility Soluble to 100 mM in DMSO and to 50 mM in ethanol
pka 13.75±0.20(Predicted)
form Solid
color White to off-white
BRN 1540211
InChIKey BMPDWHIDQYTSHX-UHFFFAOYSA-N
CAS DataBase Reference 29331-92-8
FDA UNII XFX1A5KJ3V

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS09
Signal word  Danger
Hazard statements  H411
Precautionary statements  P273-P391-P501
Hazard Codes  N,Xn,F
Risk Statements  51/53-36-20/21/22-11
Safety Statements  61-36/37-26-16
RIDADR  UN 3077 9 / PGIII
WGK Germany  3

10,11-DIHYDRO-10-HYDROXYCARBAZEPINE price More Price(31)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR3294 Licarbazepine pharmaceutical secondary standard, certified reference material 29331-92-8 50MG $344 2024-03-01 Buy
Sigma-Aldrich D-091 10,11-Dihydro-10-Hydroxycarbamazepine solution 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant? 29331-92-8 1mL $140 2024-03-01 Buy
Sigma-Aldrich 61347 10,11-Dihydro-10-hydroxycarbamazepine analytical standard 29331-92-8 25mg $1000 2024-03-01 Buy
Cayman Chemical 18467 10,11-dihydro-10-hydroxy Carbamazepine ≥98% 29331-92-8 5mg $50 2024-03-01 Buy
Cayman Chemical 18467 10,11-dihydro-10-hydroxy Carbamazepine ≥98% 29331-92-8 10mg $94 2024-03-01 Buy
Product number Packaging Price Buy
PHR3294 50MG $344 Buy
D-091 1mL $140 Buy
61347 25mg $1000 Buy
18467 5mg $50 Buy
18467 10mg $94 Buy

10,11-DIHYDRO-10-HYDROXYCARBAZEPINE Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

10,11-dihydro-10-hydroxy Carbamazepinee is the active metabolite of oxcarbazepine . Oxcarbazepine is rapidly and almost completely converted to 10,11-dihydro-10-hydroxycarbamazepine, which then demonstrates anticonvulsant efficacy by modulating several ion channels and receptors. ?10,11-dihydro-10-hydroxy Carbamazepine is reported to inhibit both voltage-gated Na+ and Ca2+ channels, to potentiate voltage-gated K+ channels, to antagonize adenosine A1 receptors, to increase dopaminergic transmission, and to inhibit glutamate release.

Uses

A labelled metabolite of Oxcarbazepine

Uses

A metabolite of Oxcarbazepine

Definition

ChEBI: A dibenzoazepine that is 5H-dibenzo[b,f]azepine, reduced across the C-10,11 positions and carrying a carbamoyl substituent at the azepine nitrogen and a hydroxy function at C-10. A voltage-gated sodium channel b ocker with anticonvulsant and mood-stabilizing effects, it is related to oxcarbazepine and is an active metabolite of oxcarbazepine.

storage

Store at RT

10,11-DIHYDRO-10-HYDROXYCARBAZEPINE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 143)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 18779 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55
Nanjing ChemLin Chemical Industry Co., Ltd.
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CONIER CHEM AND PHARMA LIMITED
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career henan chemical co
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Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34553 58
Dayang Chem (Hangzhou) Co.,Ltd.
571-88938639 +8617705817739 info@dycnchem.com China 52849 58
Zhejiang J&C Biological Technology Co.,Limited
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sgtlifesciences pvt ltd
+8617013299288 dj@sgtlifesciences.com China 12373 58
Nanjing Doge Biomedical Technology Co., Ltd
+86-25-58227606 +86-15305155328 sales@dogechemical.com China 4128 58

View Lastest Price from 10,11-DIHYDRO-10-HYDROXYCARBAZEPINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
10,11-DIHYDRO-10-HYDROXYCARBAZEPINE pictures 2020-02-01 10,11-DIHYDRO-10-HYDROXYCARBAZEPINE
29331-92-8
US $3.00 / KG 1KG 98% 100KG Career Henan Chemical Co
5-Carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepine-10-ol 6-hydroxy-5,6-dihydrobenzo[b][1]benzazepine-11-carboxamide 10,11-Dihydro-10-hydroxy-5H-dibenz(Z)[b,f]azepin-5-carboxamide 10-hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxaMide 10,11-Dihydro-10-hydroxy (±)-10-Hydroxy-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxaMide 5H-Dibenz[b,f]azepine-5-carboxaMide,10,11-dihydro-10-hydroxy- 10,11-Dihydro-10-Hydroxycarbamazepine solution 10,11-Dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide 10-Hydroxy-10,11-dihydrocarbamezepine BIA 2-005 GP 47779 Licarbazepine 10,11-Dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide-d3 10,11-Dihydro-10-hydroxycarbazepine-d3 10-Hydroxy-10,11-dihydrocarbamezepine-d3 BIA 2-005-d3 GP 47779-d3 LICARBAZEPINE SEE 16178912 Hydroxycarbamazepine Oxcarbazepine Hydroxy Impurity 5-hydroxy-5,6-dihydrobenzo[b][1]benzazepine-11-carboxamide 10-Hydroxy-10,11-dihydrocarbamazepi Dihydrohydroxy carbamazepine-D4 10,11-hydroxy-10,11 Dihydrocarbamezer Licarbazepine Racemate 10,11-Dihydro-10-hydroxy-Carbamazepin (±)-10-Hydroxy-10,11-dihydro-5H-dibenz[b,f]azepine-5-carbox... 10,11-dihydro-10-Hydroxy CarbamazepineQ: What is 10,11-dihydro-10-Hydroxy Carbamazepine Q: What is the CAS Number of 10,11-dihydro-10-Hydroxy Carbamazepine Q: What is the storage condition of 10,11-dihydro-10-Hydroxy Carbamazepine Q: What are the applications of 10,11-dihydro-10-Hydroxy Carbamazepine 10,11-Dihydro-10-hydroxy carbamazepine D7 1H-Benzimidazole,2-(6-methoxyethyl)- (±) -10,11-Dihydro-10-hydroxy-5H-dibenzo[b,f]azepine-5-carboxamide 10,11-Dihydro-10-hydroxycarbamazepine in methanol 29331-92-8 84006-10-4 C15H11D3N2O2 Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals Isotope Labeled Compounds