10,11-DIHYDRO-10-HYDROXYCARBAZEPINE
- CAS No.
- 29331-92-8
- Chemical Name:
- 10,11-DIHYDRO-10-HYDROXYCARBAZEPINE
- Synonyms
- GP 47779;BIA 2-005;GP 47779-d3;BIA 2-005-d3;Licarbazepine;Hydroxycarbamazepine;Licarbazepine Racemate;10,11-Dihydro-10-hydroxy;LICARBAZEPINE SEE 16178912;Oxcarbazepine Hydroxy Impurity
- CBNumber:
- CB0500702
- Molecular Formula:
- C15H14N2O2
- Molecular Weight:
- 254.28
- MDL Number:
- MFCD00871817
- MOL File:
- 29331-92-8.mol
- MSDS File:
- SDS
Melting point | 186-189°C |
---|---|
Boiling point | 431.3±55.0 °C(Predicted) |
Density | 1.336 |
Flash point | 2℃ |
storage temp. | -20°C |
solubility | Soluble to 100 mM in DMSO and to 50 mM in ethanol |
pka | 13.75±0.20(Predicted) |
form | Solid |
color | White to off-white |
BRN | 1540211 |
InChIKey | BMPDWHIDQYTSHX-UHFFFAOYSA-N |
CAS DataBase Reference | 29331-92-8 |
FDA UNII | XFX1A5KJ3V |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS09 |
---|---|
Signal word | Danger |
Hazard statements | H411 |
Precautionary statements | P273-P391-P501 |
Hazard Codes | N,Xn,F |
Risk Statements | 51/53-36-20/21/22-11 |
Safety Statements | 61-36/37-26-16 |
RIDADR | UN 3077 9 / PGIII |
WGK Germany | 3 |
10,11-DIHYDRO-10-HYDROXYCARBAZEPINE price More Price(31)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | PHR3294 | Licarbazepine pharmaceutical secondary standard, certified reference material | 29331-92-8 | 50MG | $344 | 2024-03-01 | Buy |
Sigma-Aldrich | D-091 | 10,11-Dihydro-10-Hydroxycarbamazepine solution 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant? | 29331-92-8 | 1mL | $140 | 2024-03-01 | Buy |
Sigma-Aldrich | 61347 | 10,11-Dihydro-10-hydroxycarbamazepine analytical standard | 29331-92-8 | 25mg | $1000 | 2024-03-01 | Buy |
Cayman Chemical | 18467 | 10,11-dihydro-10-hydroxy Carbamazepine ≥98% | 29331-92-8 | 5mg | $50 | 2024-03-01 | Buy |
Cayman Chemical | 18467 | 10,11-dihydro-10-hydroxy Carbamazepine ≥98% | 29331-92-8 | 10mg | $94 | 2024-03-01 | Buy |
10,11-DIHYDRO-10-HYDROXYCARBAZEPINE Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
10,11-dihydro-10-hydroxy Carbamazepinee is the active metabolite of oxcarbazepine . Oxcarbazepine is rapidly and almost completely converted to 10,11-dihydro-10-hydroxycarbamazepine, which then demonstrates anticonvulsant efficacy by modulating several ion channels and receptors. ?10,11-dihydro-10-hydroxy Carbamazepine is reported to inhibit both voltage-gated Na+ and Ca2+ channels, to potentiate voltage-gated K+ channels, to antagonize adenosine A1 receptors, to increase dopaminergic transmission, and to inhibit glutamate release.
Uses
A labelled metabolite of Oxcarbazepine
Uses
A metabolite of Oxcarbazepine
Definition
ChEBI: A dibenzoazepine that is 5H-dibenzo[b,f]azepine, reduced across the C-10,11 positions and carrying a carbamoyl substituent at the azepine nitrogen and a hydroxy function at C-10. A voltage-gated sodium channel b ocker with anticonvulsant and mood-stabilizing effects, it is related to oxcarbazepine and is an active metabolite of oxcarbazepine.
storage
Store at RT
10,11-DIHYDRO-10-HYDROXYCARBAZEPINE Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18779 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29811 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34553 | 58 |
Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | China | 52849 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12373 | 58 |
Nanjing Doge Biomedical Technology Co., Ltd | +86-25-58227606 +86-15305155328 | sales@dogechemical.com | China | 4128 | 58 |
View Lastest Price from 10,11-DIHYDRO-10-HYDROXYCARBAZEPINE manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2020-02-01 | 10,11-DIHYDRO-10-HYDROXYCARBAZEPINE
29331-92-8
|
US $3.00 / KG | 1KG | 98% | 100KG | Career Henan Chemical Co |
- 10,11-DIHYDRO-10-HYDROXYCARBAZEPINE
29331-92-8
- US $3.00 / KG
- 98%
- Career Henan Chemical Co