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KRN7000

KRN7000 Structure
KRN7000 structure
CAS No.
158021-47-7
Chemical Name:
KRN7000
Synonyms
Α-GALACTOSYLCERAMIDE;S34;KRN7000;α-Galactosyl Ceramide;alpha-D-Galactosylceramide;alpha-Galactosylceramide, NKT cell stimulator;alpha-Galactosylceramide(a-Gal-Cer) (synthetic);α-Galactosyl Ceramide Supplier: Funakoshi Co. Ltd.;1-O-(α-D-galactosyl)-N-hexacosanoylphytosphingosine;1-O-(alpha-D-galactosyl)-N-hexacosanoylphytosphingosine
CBNumber:
CB0501572
Molecular Formula:
C50H99NO9
Molecular Weight:
858.32
MDL Number:
MFCD00939559
MOL File:
158021-47-7.mol
MSDS File:
SDS
Last updated:2024-11-08 20:21:46
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KRN7000 Properties

Melting point 125-130°C
Boiling point 939.8±65.0 °C(Predicted)
Density 1.04±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Pyridine (Slightly, Heated)
form White solid.
pka 12.92±0.70(Predicted)
color White to Pale Beige
Stability Hygroscopic
CAS DataBase Reference 158021-47-7
NCI Dictionary of Cancer Terms KRN7000
FDA UNII WX671898JF

SAFETY

Risk and Safety Statements

WGK Germany  3
HS Code  2940.00.6000

KRN7000 price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 67576 (2S,3S,4R)-1-O-(α-D-Galactosyl)-N-hexacosanoyl-2-amino-1,3,4-octadecanetriol ≥95% (TLC) 158021-47-7 1mg $1100 2024-03-01 Buy
TCI Chemical G0509 α-Galactosylceramide >95.0%(HPLC) 158021-47-7 1mg $198 2024-03-01 Buy
Cayman Chemical 11208 KRN 7000 ≥96% 158021-47-7 500 μg $197 2024-03-01 Buy
Cayman Chemical 11208 KRN 7000 ≥96% 158021-47-7 1mg $253 2024-03-01 Buy
Cayman Chemical 11208 KRN 7000 ≥96% 158021-47-7 250μg $115 2022-04-27 Buy
Product number Packaging Price Buy
67576 1mg $1100 Buy
G0509 1mg $198 Buy
11208 500 μg $197 Buy
11208 1mg $253 Buy
11208 250μg $115 Buy

KRN7000 Chemical Properties,Uses,Production

Description

KRN 7000 is a potent synthetic α-galactosylceramide, which, in association with the antigen-presenting CD1d protein, activates NKT immune cells. As these cells have important roles in the rejection of malignant tumors and in the regulation of several autoimmune diseases, KRN 7000 has activity in many diseases, including cancer, lupus, diabetes, malaria, and tuberculosis.

Chemical Properties

White Solid

Uses

Galactosylceramides play an important roles in promoting the regulation of nerve cells, regulating protein kinase C activities and modulating the function of the hormone receptor. It has shown to have significant immunostimulatory and anti-umor activity in mice with liver metastasis of the Colon26 adenocarcinoma.

Uses

KRN 7000 is a potent synthetic α-galactosylceramide, which, in association with the antigen-presenting CD1d protein, activates NKT immune cells. As these cells have important roles in the rejection of malignant tumors and in the regulation of several autoimmune diseases, KRN 7000 has activity in many diseases, including cancer, lupus, diabetes, malaria, and tuberculosis.

Definition

ChEBI: A glycophytoceramide having an alpha-D-galactosyl residue at the O-1 position and a hexacosanoyl group attached to the nitrogen.

storage

-20°C

KRN7000 Preparation Products And Raw materials

Raw materials

Preparation Products

KRN7000 Suppliers

Global( 104)Suppliers
Supplier Tel Email Country ProdList Advantage
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207 sales@molcore.com China 49734 58
Jinan Carbotang Biotech Co.,Ltd. 		+8615866703830 figo.gao@foxmail.com China 8497 58
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19553 58
GlycoPharm.LLC 		+86-27-63498076 sale@glycolipidpharm.com CHINA 158 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30233 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38631 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		13417589054 trendseenbio@gmail.com China 11681 58
Shanghai Acmec Biochemical Technology Co., Ltd. 		+86-18621343501; +undefined18621343501 product@acmec-e.com China 33338 58
Supplier Advantage
Hangzhou MolCore BioPharmatech Co.,Ltd. 		58
Jinan Carbotang Biotech Co.,Ltd. 		58
BOC Sciences 		58
GlycoPharm.LLC 		58
TargetMol Chemicals Inc. 		58
Career Henan Chemica Co 		58
InvivoChem 		58
TargetMol Chemicals Inc. 		58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		58
Shanghai Acmec Biochemical Technology Co., Ltd. 		58

View Lastest Price from KRN7000 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
KRN7000 pictures 2024-11-21 KRN7000
158021-47-7
 US $0.00-0.00 / G 1G 98% kgs Hangzhou MolCore BioPharmatech Co.,Ltd.
α-Galactosylceramide pictures 2024-11-08 α-Galactosylceramide
158021-47-7
 US $413.00 / mg 98% 10g TargetMol Chemicals Inc.
α-Galactosylceramide pictures 2024-11-08 α-Galactosylceramide
158021-47-7
 US $413.00 / mg 98% 10g TargetMol Chemicals Inc.
  • KRN7000 pictures
  • KRN7000
    158021-47-7
  • US $0.00-0.00 / G
  • 98%
  • Hangzhou MolCore BioPharmatech Co.,Ltd.

158021-47-7(KRN7000)Related Search:

C16 CERAMIDE C18 CERAMIDE N-(2-hydroxypropyl)stearamide C14 Dihydroceramide DL-ERYTHRO-DIHYDROSPHINGOSINE
C2 DIHYDROCERAMIDE Phytosphingosine C14 CERAMIDE KRN7000 C22 Dihydroceramide
C22 Ceramide N-PALMITOYL SERINOL DL-1,3-DIHYDROXY-2-AMINO-OCTADECANE N-(2-HYDROXY-1R-METHYLETHYL)-HEXADECANAMIDE N-(2R-HYDROXYPROPYL)-HEXADECANAMIDE
C18 Dihydroceramide C4 Dihydroceramide N-LIGNOCEROYL-DL-DIHYDROSPHINGOSINE

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KRN7000 N-[(1S,2S,3R)-1-[(α-D-Galactopyranosyloxy)Methyl]-2,3-dihydroxyheptadecyl]hexacosanaMide 1-O-(alpha-D-galactosyl)-N-hexacosanoylphytosphingosine (2S,3S,4R)-1-O-(α-D-Galactosyl)-N-hexacosanoyl-2-amino-1,3,4-octadecanetriol (2S,3S,4R)-1-O-(α-D-Galactopyranosyl)-N-hexacosanoyl-2-amino-1,3,4-octadecanetriol Synonym:α-GalCer or KRN7000 Hexacosanamide, N-[(1S,2S,3R)-1-[(α-D-galactopyranosyloxy)methyl]-2,3-dihydroxyheptadecyl]- alpha-Galactosylceramide(a-Gal-Cer) (synthetic) α-Galactosyl Ceramide Α-GALACTOSYLCERAMIDE 1-O-(α-D-galactosyl)-N-hexacosanoylphytosphingosine S34 α-Galactosyl Ceramide Supplier: Funakoshi Co. Ltd. alpha-D-Galactosylceramide N-((2S,3S,4R)-3,4-Dihydroxy-1-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)octadecan-2-yl)hexacosanamide alpha-Galactosylceramide, NKT cell stimulator 158021-47-7 C50H99NO9 Amino Acids & Derivatives Protein Kinase Inhibitors and Activators Amino Acids 13C, 2H, 15N