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Tanomastat

Tanomastat structure

CAS No.: 179545-77-8

Chemical Name:: Tanomastat

Synonyms: D03802;TANOMASTAT;Tanomastat (usan/inn);(S)-4'-Chloro-g-oxo-a-[(phenylthio)methyl][1,1'-biphenyl]-4-butanoic acid;(S)-4-[4-(4-Chlorophenyl)phenyl]-4-oxo-2-(phenylsulfanylmethyl)butanoic acid;1,1'-Biphenyl]-4-butanoic acid, 4'-chloro-γ-oxo-α-[(phenylthio)methyl]-, (αS)-;BAY12-9566,(S)-4Chloro-g-oxo-a-[(phenylthio)methyl][1,1biphenyl]-4-butanoicAcid;[1,1'-Biphenyl]-4-butanoic acid, 4'-chloro-γ-oxo-α-[(phenylthio)methyl]-, (αS)-;(S)-4-(4'-Chloro-[1,1'-biphenyl]-4-yl)-4-oxo-2-((phenylthio)methyl)butanoic acid

CBNumber:: CB0506810

Molecular Formula:: C23H19ClO3S

Molecular Weight:: 410.91

MDL Number:: MFCD00948600

MOL File:: 179545-77-8.mol

MSDS File:: SDS

Last updated:2024-10-23 13:36:13

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Tanomastat Properties

Melting point	110-110.5°C
Boiling point	620.1±55.0 °C(Predicted)
Density	1.33±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,2-8°C
solubility	Acetone (Slightly), Chloroform (Slightly), Ethyl Acetate (Slightly)
form	Solid
pka	4.01±0.23(Predicted)
color	White to Off-White
CAS DataBase Reference	179545-77-8
FDA UNII	AM1ZX94EXH
NCI Drug Dictionary	tanomastat

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501

NFPA 704

	0
2		0

Tanomastat price More Price(14)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	19258	Tanomastat ≥98%	179545-77-8	500μg	$37	2024-03-01	Buy
Cayman Chemical	19258	Tanomastat ≥98%	179545-77-8	1mg	$68	2024-03-01	Buy
Cayman Chemical	19258	Tanomastat ≥98%	179545-77-8	5mg	$213	2024-03-01	Buy
Cayman Chemical	19258	Tanomastat ≥98%	179545-77-8	10mg	$388	2024-03-01	Buy
TRC	T006900	Tanomastat	179545-77-8	5mg	$180	2021-12-16	Buy

Product number	Packaging	Price	Buy
19258	500μg	$37	Buy
19258	1mg	$68	Buy
19258	5mg	$213	Buy
19258	10mg	$388	Buy
T006900	5mg	$180	Buy

Tanomastat Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

A Matrix Metalloproteinase inhibitor. An angiogenesis inhibitor. Optical Rotation +82?(C 1.5 acetone)

Uses

A Matrix Metalloproteinase inhibitor. An angiogenesis inhibitor.Optical Rotation +82° (C 1.5 acetone).

Uses

Tanomastat is an orally available, non-peptidic inhibitor of matrix metalloproteinase-2 (MMP-2), MMP-3, and MMP-9 (Kis = 11, 143, and 301 nM, respectively). It is active in various animal models of tumor metastasis and has been used in a phase III clinical trial in pancreatic, SCLC, NSCLC, and ovarian cancer patients.

Definition

ChEBI: Tanomastat is an organochlorine compound and a member of biphenyls.

Tanomastat Preparation Products And Raw materials

Raw materials

Preparation Products

Tanomastat Suppliers

Global( 46)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49374	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30238	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6312	58
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3135	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43340	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32321	50
Beijing HuaMeiHuLiBiological Chemical	010-56205725	waley188@sohu.com	China	12335	58
Sichuan Wei Keqi Biological Technology Co., Ltd.	028-81700200 18116577057	3003855609@qq.com	China	7887	56

Supplier	Advantage
CONIER CHEM AND PHARMA LIMITED	58
TargetMol Chemicals Inc.	58
Career Henan Chemica Co	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58
Nantong HI-FUTURE Biology Co., Ltd.	58
LEAPCHEM CO., LTD.	58
J & K SCIENTIFIC LTD.	76
Chemsky（shanghai）International Co.,Ltd.	50
Beijing HuaMeiHuLiBiological Chemical	58
Sichuan Wei Keqi Biological Technology Co., Ltd.	56

View Lastest Price from Tanomastat manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-10-24	Tanomastat 179545-77-8	US $170.00-540.00 / mg			10g	TargetMol Chemicals Inc.

Tanomastat
179545-77-8
US $170.00-540.00 / mg
TargetMol Chemicals Inc.

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TANOMASTAT BAY12-9566,(S)-4Chloro-g-oxo-a-[(phenylthio)methyl][1,1biphenyl]-4-butanoicAcid (S)-4'-Chloro-g-oxo-a-[(phenylthio)methyl][1,1'-biphenyl]-4-butanoic acid (S)-4-[4-(4-Chlorophenyl)phenyl]-4-oxo-2-(phenylsulfanylmethyl)butanoic acid D03802 Tanomastat (usan/inn) (S)-4-(4'-Chloro-[1,1'-biphenyl]-4-yl)-4-oxo-2-((phenylthio)methyl)butanoic acid [1,1'-Biphenyl]-4-butanoic acid, 4'-chloro-γ-oxo-α-[(phenylthio)methyl]-, (αS)- 1,1'-Biphenyl]-4-butanoic acid, 4'-chloro-γ-oxo-α-[(phenylthio)methyl]-, (αS)- 179545-77-8 C23H19ClO3S Chiral Reagents Inhibitors Intermediates & Fine Chemicals Pharmaceuticals Sulfur & Selenium Compounds