PIVMECILLINAM HYDROCHLORIDE
- CAS No.
- Chemical Name:
- PIVMECILLINAM HYDROCHLORIDE
- Synonyms
- PIVMECILLINAM HYDROCHLORIDE
- CBNumber:
- CB0587932
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
| FDA UNII | 48FX7N21H2 |
|---|
PIVMECILLINAM HYDROCHLORIDE Chemical Properties,Uses,Production
Uses
Pivmecillinam is an orally active prodrug of Amdinocillin (A576300), an broad spectrum penicillin antibiotic that binds specifically to penicillin binding protein 2.
Clinical Use
Antibacterial agent
Drug interactions
Potentially hazardous interactions with other drugs
Antiepileptics: avoid concomitant use with valproate.
Methotrexate: penicillins can reduce the excretion of
methotrexate (increased risk of toxicity).
Probenecid: reduces excretion of penicillins.
Metabolism
Pivmecillinam is rapidly hydrolysed to mecillinam which is the active drug, plus pivalic acid and formaldehyde. About 45% of a dose may be excreted in the urine as mecillinam, mainly within the first 6 hours. Mecillinam is partly excreted with bile, giving rise to biliary concentrations about 3 times the serum levels.
PIVMECILLINAM HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
PIVMECILLINAM HYDROCHLORIDE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Shizhou Biology Technology Co.,Ltd | 13675144456 | sean.lv@synzest.com | China | 10784 | 58 |
| Supplier | Advantage |
|---|---|
| Nanjing Shizhou Biology Technology Co.,Ltd | 58 |