2,2-Dimethylbutyric acid
- CAS No.
- 595-37-9
- Chemical Name:
- 2,2-Dimethylbutyric acid
- Synonyms
- 2,2-DIMETHYLBUTANOIC ACID;Dimebutic acid;NEOHEXANOIC ACID;DiMethylbutyric Aci;2,2-Dimethylbutanoic;2,2-Dimethylbuttersαure;2,2-two Methyl butyrate;DIMETHYLETHYLACETIC ACID;2,2-DIMETHYLBUTYRIC ACID;Butanoicacid,2,2-dimethyl-
- CBNumber:
- CB0675444
- Molecular Formula:
- C6H12O2
- Molecular Weight:
- 116.16
- MDL Number:
- MFCD00004200
- MOL File:
- 595-37-9.mol
- MSDS File:
- SDS
| Melting point | -14°C |
|---|---|
| Boiling point | 94-96 °C/5 mmHg (lit.) |
| Density | 0.928 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | 175 °F |
| storage temp. | Refrigerator |
| solubility | Chloroform (Sparingly), Methanol (Slightly) |
| pka | pK1:5.03 (18°C) |
| form | Liquid |
| color | Clear colorless to pale yellow |
| Specific Gravity | 0.928 |
| Decomposition | 176-178 ºC |
| BRN | 1720666 |
| InChIKey | VUAXHMVRKOTJKP-UHFFFAOYSA-N |
| LogP | 1-2.3 at 20℃ and pH2.5-6.7 |
| CAS DataBase Reference | 595-37-9(CAS DataBase Reference) |
| FDA UNII | AY606CN05O |
| NIST Chemistry Reference | Butanoic acid, 2,2-dimethyl-(595-37-9) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36/37-36 | |||||||||
| RIDADR | 3265 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29156000 | |||||||||
| NFPA 704 |
|
2,2-Dimethylbutyric acid price More Price(25)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | D152609 | 2,2-Dimethylbutyric acid 96% | 595-37-9 | 25ml | $41.16 | 2024-03-01 | Buy |
| TCI Chemical | D2429 | 2,2-Dimethylbutyric Acid >96.0%(GC)(T) | 595-37-9 | 25mL | $32 | 2024-03-01 | Buy |
| TCI Chemical | D2429 | 2,2-Dimethylbutyric Acid >96.0%(GC)(T) | 595-37-9 | 500mL | $315 | 2024-03-01 | Buy |
| Alfa Aesar | A17072 | 2,2-Dimethylbutyric acid, 97% | 595-37-9 | 10g | $23.65 | 2024-03-01 | Buy |
| Alfa Aesar | A17072 | 2,2-Dimethylbutyric acid, 97% | 595-37-9 | 50g | $64.65 | 2024-03-01 | Buy |
2,2-Dimethylbutyric acid Chemical Properties,Uses,Production
Description
2,2-Dimethylbutyric acid is the intermediate of crucial importance in producing cardiovascular drugs, such as Simvastatin and agricultural chemicals, miticide spiral shell mite ester. It can also be used for rubber, dyestuff, etc. industries simultaneously. All 2,2-Dimethylbutyric acid production processes are that primary isoamyl alcohol and formic acid react under sulfuric acid catalysis. This technique's shortcoming is to produce a large amount of Waste Sulfuric Acids.
Chemical Properties
Colorless to light yellow or light green liquid
Uses
2,2-Dimethylbutyrate (DMB) is a potential treatment for thalassemia and hemoglobinopathies.
Definition
ChEBI: A branched-chain fatty acid and metabolite of the lactone prodrug simvastatin, whose sodium salt is potentially useful for the treatment of thalassaemias and haemoglobinopathies.
Synthesis Reference(s)
Synthetic Communications, 19, p. 1945, 1989 DOI: 10.1080/00397918908052587
Synthesis
Adding 15 to 25 parts by weight of solid acid catalyst, 150 to 170 parts by weight of isoamyl alcohol, and 15 to 20 parts by weight of sulfuric acid into a high-pressure reactor, evenly stirring to obtain a reaction mixture, introducing nitrogen gas into the reactor, introducing CO into the reaction mixture at a temperature of 85 to 90 ℃, maintaining a pressure of 0.1 to 0.15 MPa until the pressure starts to rise; cooling to the room temperature, introducing nitrogen gas into the reactor to replace the CO gas, discharging materials from the reactor, filtering to obtain the solid acidified catalyst; adding 5 to 15 parts by weight of saturated sodium chloride water solution into the filtrate, evenly stirring, allowing the system to stand still, removing the lower water layer, and rectifying the upper oil layer to obtain the product 2,2-Dimethylbutyric acid.
2,2-Dimethylbutyric acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shijiazhuang Dowell Chemical Co.,Ltd | +8618633820607 | sell@dowechem.com | China | 90 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5868 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18137 | 58 |
| Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 973 | 58 |
| Shandong Deshang Chemical Co., Ltd. | +86-0531-8875-2665 +8613153039501 | info@deshangchem.com | China | 662 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-+86-371-66670886 | info@dakenam.com | China | 19805 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21628 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29858 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
View Lastest Price from 2,2-Dimethylbutyric acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-27 | 2,2-Dimethylbutyric acid
595-37-9
|
US $45.00 / kg | 1kg | 99% | 20 tons | Hebei Zhuanglai Chemical Trading Co Ltd | |
 |
2025-04-15 | 2,2-Dimethylbutyric acid
595-37-9
|
US $0.00-0.00 / KG | 1KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-04-04 | 2,2-Dimethylbutyric acid
595-37-9
|
US $0.00-0.00 / KG | 1KG | 98% | 1ton | Henan Aochuang Chemical Co.,Ltd.
|
-
- 2,2-Dimethylbutyric acid
595-37-9
- US $45.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co Ltd
-
- 2,2-Dimethylbutyric acid
595-37-9
- US $0.00-0.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 2,2-Dimethylbutyric acid
595-37-9
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.