A 61603 HYDROBROMIDE
- CAS No.
- 107756-30-9
- Chemical Name:
- A 61603 HYDROBROMIDE
- Synonyms
- A 61603;A 61603 HYDROBROMIDE;N-[5-(4,5-DIHYDRO-1H-IMIDAZOL-2-YL)-2-HYDROXY-5,6,7,8-TETRAHYDRONAPHTHALEN-1-YL]METHANESULFONAMIDE HYDROBROMIDE;N-(5-(4,5-Dihydro-(1H)-imidazol-2-yl)-2-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl)methanesulfonamidehydrobromide
- CBNumber:
- CB0723691
- Molecular Formula:
- C14H20BrN3O3S
- Molecular Weight:
- 390.3
- MDL Number:
- MFCD02262217
- MOL File:
- 107756-30-9.mol
- MSDS File:
- SDS
A 61603 HYDROBROMIDE price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 17358 | A-61603 ≥98% | 107756-30-9 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 17358 | A-61603 ≥98% | 107756-30-9 | 5mg | $100 | 2024-03-01 | Buy |
| Cayman Chemical | 17358 | A-61603 ≥98% | 107756-30-9 | 10mg | $139 | 2024-03-01 | Buy |
| Tocris | 1052 | A61603hydrobromide | 107756-30-9 | 10 | $195 | 2021-12-16 | Buy |
| Tocris | 1052 | A61603hydrobromide | 107756-30-9 | 50 | $818 | 2021-12-16 | Buy |
A 61603 HYDROBROMIDE Chemical Properties,Uses,Production
Uses
A 61603 is a selective α1A-adrenergic receptor agonist.
Biological Activity
Potent α -adrenoceptor agonist that is at least 35-fold more potent at α 1A than at α 1B or α 1D sites. Induces dose response increases in spontaneous Ca 2+ transients in rat ventricular myocytes in vitro (EC 50 = 6.9 nmol/L). Also available as part of the α 1 -Adrenoceptor Tocriset™ .
storage
Desiccate at +4°C
References
[1]. knepper sm, buckner sa, brune me, et al. a-61603, a potent alpha 1-adrenergic receptor agonist, selective for the alpha 1a receptor subtype. j pharmacol exp ther, 1995, 274(1): 97-103.
[2]. meyer md, altenbach rj, hancock aa, et al. synthesis and in vitro characterization of n-[5-(4,5-dihydro-1h-imidazol-2-yl)-2-hydroxy-5,6,7,8- tetrahydronaphthalen-1-yl]methanesulfonamide and its enantiomers: a novel selective alpha 1a receptor agonist. j med chem, 1996, 39(20): 4116-4119.
[3]. luo dl, gao j, fan ll, et al. receptor subtype involved in alpha 1-adrenergic receptor-mediated ca2+ signaling in cardiomyocytes. acta pharmacol sin, 2007, 28(7): 968-974.
[4]. martínez-salas sg1, campos-peralta jm, pares-hipolito j, et al. alpha1a-adrenoceptors predominate in the control of blood pressure in mouse mesenteric vascular bed. auton autacoid pharmacol, 2007, 27(3): 137-142.
A 61603 HYDROBROMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
A 61603 HYDROBROMIDE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32165 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30240 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52925 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15839 | 69 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8447 | 60 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9806 | 58 |
| BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11217 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44808 | 58 |
| Jinan Jiuli Biotechnology Co. , Ltd. | 15865264761 | 486064515@qq.com | China | 3651 | 58 |
