12(S)-HHT
- CAS No.
- 54397-84-1
- Chemical Name:
- 12(S)-HHT
- Synonyms
- 12-HHT;12-HHTRE;12(S)-HHT;12(S)-HHTRE;12(S)-HHTrE (12(S)-HHT);KUKJHGXXZWHSBG-WBGSEQOASA-N;12(S)-HHTrE Lipid Maps MS Standard;12-HYDROXY-HEPTA- DECATRIENOIC ACID;12(S)-HYDROXYHEPTADECA-5Z,8E,10E-TRIENOIC ACID;12(S)-hydroxy-5(Z),8(E),10(E)-*heptadecatrienoic
- CBNumber:
- CB0726021
- Molecular Formula:
- C17H28O3
- Molecular Weight:
- 280.4
- MDL Number:
- MFCD00057833
- MOL File:
- 54397-84-1.mol
Boiling point | 451.8±45.0 °C(Predicted) |
---|---|
Density | 0.992±0.06 g/cm3(Predicted) |
storage temp. | −20°C |
solubility | 0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml |
form | ethanol solution |
pka | 4.75±0.10(Predicted) |
color | Colorless to light yellow |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
Hazard Codes | F,Xi | |||||||||
Risk Statements | 11-36/37/38 | |||||||||
Safety Statements | 16-26-36 | |||||||||
RIDADR | UN 1170 3/PG 2 | |||||||||
WGK Germany | 3 | |||||||||
NFPA 704 |
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12(S)-HHT price More Price(7)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | H1640 | 12(S)-Hydroxy-(5Z,8E,10E)-heptadecatrienoic acid ≥93% (HPLC), ethanol solution | 54397-84-1 | 50μg | $258 | 2024-03-01 | Buy |
Cayman Chemical | 34590 | 12(S)-HHTrE ≥95% | 54397-84-1 | 25μg | $121 | 2024-03-01 | Buy |
Cayman Chemical | 34590 | 12(S)-HHTrE ≥95% | 54397-84-1 | 50μg | $230 | 2024-03-01 | Buy |
Cayman Chemical | 34590 | 12(S)-HHTrE ≥95% | 54397-84-1 | 100μg | $433 | 2024-03-01 | Buy |
Cayman Chemical | 34590 | 12(S)-HHTrE ≥95% | 54397-84-1 | 250μg | $961 | 2024-03-01 | Buy |
12(S)-HHT Chemical Properties,Uses,Production
Uses
12(S)-HHTrE is a metabolite of arachidonic acid (A765000), which is an essential fatty acid and a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes. Arachidonic Acid occurs in liver, brain, glandular organs, and depot fats of animals, in small amounts in human depot fats, and Arachidonic Acid is also a constituent of animal phosphatides.
Uses
12(S)-HHTrE is an unusual product of the cyclooxygenase (COX) pathway and one of the primary arachidonic acid metabolites of the human platelet. It is biosynthesized by thromboxane synthase (TX synthase) from prostaglandin H2 (PGH2) concurrently with TXA2. The biological role of 12(S)-HHTrE is uncertain. It is avidly oxidized to 12-oxoHTrE by porcine 15-hydroxy PGDH.
Definition
ChEBI: A trienoic fatty acid that consists of (5Z,8E,10E)-heptadeca-5,8,10-trienoic acid bearing an additional 12S-hydroxy substituent.
12(S)-HHT Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30250 | 58 |
Alfa Chemistry | Info@alfa-chemistry.com | United States | 24072 | 58 | |
Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33350 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40068 | 58 |
Shanghai Boyle Chemical Co., Ltd. | 021-50182298 021-50180596 | sales@boylechem.com | China | 2210 | 55 |
3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
Yichang Zhongyitai Trading Co., Ltd. | 0717-6449896 13886658719 | root@zhongyitai.com | China | 1977 | 58 |
Alfa Chemistry | 1-516-6625404 | support@alfa-chemistry.com | United States | 9171 | 60 |
Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |