Indole-5-carboxylic acid
- CAS No.
- 1670-81-1
- Chemical Name:
- Indole-5-carboxylic acid
- Synonyms
- 1H-INDOLE-5-CARBOXYLIC ACID;JACS-1670-81-1;5-CARBOXYINDOLE;5-Carboxy-1H-indole;RARECHEM AL BO 0206;TIMTEC-BB SBB003951;Indolecarboxylicacid,5-;5-INDOLECARBOXYLIC ACID;INDOLE-5-CARBOXYLIC ACID;INDOLE-5-CARBOXYLIC AICD
- CBNumber:
- CB0736428
- Molecular Formula:
- C9H7NO2
- Molecular Weight:
- 161.16
- MDL Number:
- MFCD00005678
- MOL File:
- 1670-81-1.mol
- MSDS File:
- SDS
| Melting point | 211-213 °C (lit.) |
|---|---|
| Boiling point | 287.44°C (rough estimate) |
| Density | 1.2480 (rough estimate) |
| refractive index | 1.5050 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Soluble in ethanol (50 mg/ml), dimethyl sulfoxide and methanol. |
| pka | 4.40±0.30(Predicted) |
| form | Powder |
| color | Light beige to yellow |
| BRN | 124391 |
| InChIKey | IENZCGNHSIMFJE-UHFFFAOYSA-N |
| CAS DataBase Reference | 1670-81-1(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 36/37/38-21/22 | |||||||||
| Safety Statements | 22-24/25-36/37/39-26 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29339990 | |||||||||
| NFPA 704 |
|
Indole-5-carboxylic acid price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | I0029 | Indole-5-carboxylic Acid >98.0%(GC)(T) | 1670-81-1 | 1g | $42 | 2024-03-01 | Buy |
| TCI Chemical | I0029 | Indole-5-carboxylic Acid >98.0%(GC)(T) | 1670-81-1 | 5g | $81 | 2024-03-01 | Buy |
| Alfa Aesar | A18627 | Indole-5-carboxylic acid, 98% | 1670-81-1 | 1g | $40.65 | 2024-03-01 | Buy |
| Alfa Aesar | A18627 | Indole-5-carboxylic acid, 98% | 1670-81-1 | 5g | $133 | 2024-03-01 | Buy |
| Alfa Aesar | A18627 | Indole-5-carboxylic acid, 98% | 1670-81-1 | 25g | $493.65 | 2024-03-01 | Buy |
Indole-5-carboxylic acid Chemical Properties,Uses,Production
Chemical Properties
light beige to yellow powder
Uses
Indole-5-carboxylic acid is the suitable reagent used to study the intramolecular excited state proton transfer in indole-2-carboxylic acid and indole-5-carboxylic acid in various solvents in acidic, basic, and neutral media by steady state and time resolved fluorescence spectroscopy. It may be used in the electrochemical synthesis of poly(indole-5-carboxylic acid) (PICA) films.
Uses
Reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles, as potential anticancer immunomodulators 1 Reactant for preparation of indolyl-quinolines via metal- and solvent-free autoxidative coupling reaction 2 Reactant for preparation of anthranilic acids using bromamine-B oxidant and palladium chloride catalyst 3 Reactant for synthesis of indirubin derivatives 4 Reactant for preparation of amide conjugates with ketoprofen, as inhibitors of Gli1-mediated transcription in Hedgehog pathway 5 Reactant for preparation of piperazine-bisamide analogs as human growth hormone secretagogue receptor antagonists for treatment of obesity.
Uses
Indole-5-carboxylic acid is the suitable reagent used to study the intermolecular excited state proton transfer in indole-2-carboxylic acid and indole-5-carboxylic acid in various solvents in acidic, basic, and neutral media by steady state and time resolved fluorescence spectroscopy. It may be used in the electrochemical synthesis of poly(indole-5-carboxylic acid) (PICA) films. Also used as reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles, as potential anticancer immunomodulators, synthesis of indirubin derivatives and amide conjugates with ketoprofen, as inhibitors of Gli1-mediated transcription in Hedgehog pathway.
Definition
ChEBI: Indole-5-carboxylic acid is an indolecarboxylic acid in which the carboxy group is the only substituent and is located at position 5. It has a role as a plant metabolite.
General Description
Indole-5-carboxylic acid is an indole derivative. On electropolymerization, it affords electroactive polymer film of poly(indole-5-carboxylic-acid). Different concentrations of indole-5-carboxylic acid in sulfuric acid solution has been investigated for the preventive action against mild steel corrosion. On electropolymerization it affords a trimeric product. Characterization studies of the trimeric product by 1H NMR and various one- and two-dimensional NMR techniques have been reported.
Indole-5-carboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32957 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29884 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2136 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| Nanjing jinheyou Trading Co., Ltd. | 15705188088 | admin@jheyou.com | CHINA | 1268 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17365 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34553 | 58 |
View Lastest Price from Indole-5-carboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2021-08-12 | Indole-5-carboxylic acid
1670-81-1
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2020-06-02 | Indole-5-carboxylic acid in stock Factory
1670-81-1
|
US $1.00 / KG | 1KG | TOP 3 Factory in China | Top 3 production capacity Factory | Chemwill Asia Co.,Ltd. | |
 |
2019-12-23 | Indole-5-carboxylic acid
1670-81-1
|
US $0.00 / g | 1g | 95%min | 20kg/month | Nanjing jinheyou Trading Co., Ltd. |
-
- Indole-5-carboxylic acid
1670-81-1
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- Indole-5-carboxylic acid in stock Factory
1670-81-1
- US $1.00 / KG
- TOP 3 Factory in China
- Chemwill Asia Co.,Ltd.
-
- Indole-5-carboxylic acid
1670-81-1
- US $0.00 / g
- 95%min
- Nanjing jinheyou Trading Co., Ltd.