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Triethylamine hydrochloride

Triethylamine hydrochloride structure

CAS No.: 554-68-7

Chemical Name:: Triethylamine hydrochloride

Synonyms: TRIETHYLAMMONIUM CHLORIDE;TRIETHYLAMINE HCL;Et3·HCl;[E3N]HCl;Trimethylamine Hci;Triethylamine hydroc;Triethylammoniumchlorid;Tolzaoline bydrochloride;TriethylaminHydrochlorid;triethylammomium chloride

CBNumber:: CB0767833

Molecular Formula:: C6H16ClN

Molecular Weight:: 137.65

MDL Number:: MFCD00012500

MOL File:: 554-68-7.mol

MSDS File:: SDS

Last updated:2024-12-18 13:37:16

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Triethylamine hydrochloride Properties

Melting point	261 °C (dec.)(lit.)
Boiling point	223.18°C (rough estimate)
Density	1.07
refractive index	1.4530 (estimate)
storage temp.	Store below +30°C.
solubility	1440 g/L (20°C)
form	Crystalline Powder
color	White to off-white
PH	5 (10g/l, H2O, 20℃)
Water Solubility	1440 g/L (20 ºC)
Sensitive	Hygroscopic
Merck	14,9666
BRN	3906409
InChIKey	ILWRPSCZWQJDMK-UHFFFAOYSA-N
CAS DataBase Reference	554-68-7(CAS DataBase Reference)
FDA UNII	0NX3818GCW
EPA Substance Registry System	Ethanamine, N,N-diethyl-, hydrochloride (554-68-7)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

Hazard Codes

Xi,Xn

Risk Statements

36/37/38-20/21/22

Safety Statements

26-36-36/37/39-22

WGK Germany

RTECS

YE2111500

TSCA

Yes

HS Code

29211910

Hazardous Substances Data

554-68-7(Hazardous Substances Data)

Toxicity

LDLo scu-mus: 600 mg/kg JPETAB 37,309,29

NFPA 704

	1
2		0

Triethylamine hydrochloride price More Price(23)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	90350	Triethylamine hydrochloride ≥99.0% (AT)	554-68-7	50g	$45.1	2024-03-01	Buy
Sigma-Aldrich	90350	Triethylamine hydrochloride ≥99.0% (AT)	554-68-7	1kg	$176	2024-03-01	Buy
Sigma-Aldrich	8.21135	Triethylammonium chloride for synthesis	554-68-7	5G	$40.9	2024-03-01	Buy
Sigma-Aldrich	8.21135	Triethylammonium chloride for synthesis	554-68-7	250g	$65.5	2024-03-01	Buy
Sigma-Aldrich	8.21135	Triethylammonium chloride for synthesis	554-68-7	1kg	$223	2024-03-01	Buy

Product number	Packaging	Price	Buy
90350	50g	$45.1	Buy
90350	1kg	$176	Buy
8.21135	5G	$40.9	Buy
8.21135	250g	$65.5	Buy
8.21135	1kg	$223	Buy

Triethylamine hydrochloride Chemical Properties,Uses,Production

Chemical Properties

White to off-white crystalline powder

Uses

Triethylamine Hydrochloride is a hydrochloride salt of triethyllamine (T775740). Triethylamine is used as a competing base for the separation of acidic basic and neutral drugs by reverse-phased high-performance liquid chromatography (HPLC). Triethylamine induces visual disturbances (such as foggy vision) in humans, and is also used in industry as a quenching agent in the ozonolysis of alkenes (e.g. (E)-2-Pentene [P227315]). Triethylamine is used in the purification of drugs which are pharmacologically or chemically similar through separation in reverse-phase HPLC (2).Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.

Hazard

Irritating to eyes and skin on contact. Inhalation causes irritation of the lungs and respiratory system. Targets the central nervous system, liver, kidneys, and heart. Inflammation of the eye is characterized by redness, watering, and itching. Skin inflammation is characterized by itching, scaling, reddening, or, occasionally, blistering. Harmful if ingested or inhaled. Minimize exposure to this material. Severe overexposure can result in injury or death.

Safety Profile

Moderately toxic by subcutaneousroute. When heated to decomposition it emits toxicvapors of NOx, HCl, and Clí.

Solubility in organics

Soluble in ethanol, chloroform, and alcohol. Insoluble in ether.

Purification Methods

Purify it like the bromide above. [Beilstein 4 IV 327.]

References

[1] C Spagnuolo. “Gel filtration and reactivity of sulphydryl groups of human hemoglobin in concentrated triethylamine hydrochloride solutions.” The Italian journal of biochemistry 21 4 (1972): 221–9.
[2] G. Tian, Qi-Li Yuan, Huanhuan Du. “The Effects of Benzene on the Structure and Properties of Triethylamine Hydrochloride/Chloroaluminate.” Crystals 6 1 (2021).
[3] Zhe Zhang. “Solubility Determination and Model Evaluation of Triethylamine Hydrochloride in Three Binary Mixed Solvents.” Journal of Solution Chemistry 53 10 (2024): 1353–1373.
[4] Junfeng Teng . “Measurement, correlation, and analysis of the solubility of triethylamine hydrochloride in ten pure solvents.” Journal of Molecular Liquids 390 (2023): Article 123040.

Triethylamine hydrochloride synthesis

Synthesis of Triethylamine hydrochloride from Ethylene thiourea

Triethylamine hydrochloride Preparation Products And Raw materials

Raw materials

Triethylamine

Preparation Products

2-(4-Chloromethylpiperidin-1-yl)pyrimidine-5-carboxamide ,97% Triethylenethiophosphoramide 2-(4-Methylpiperazin-1-yl)pyrimidine-5-carbaldehyde 2-(4-(Hydroxymethyl)piperidin-1-yl)pyrimidine-5-carboxamide 2-(4-Methylpiperazin-1-yl)pyrimidine-5-carbonyl chloride

Cefotaxime sodium HEPTENOPHOS 1-(5-(Hydroxymethyl)pyrimidin-2-yl)piperidin-4-ol Lisinopril Dihydrate 2-(4-Methylpiperazin-1-yl)pyrimidine-5-carboxylic acid

2-(4-Methylpiperazin-1-yl)pyrimidine-5-carbonitrile (2-(4-(Hydroxymethyl)piperidin-1-yl)pyrimidin-5-yl)methanol 2-(4-Methylpiperazin-1-yl)pyrimidine-5-carboxamide Ethyl 2-(4-methylpiperazin-1-yl)pyrimidine-5-carboxylate Phosazetim

2-(4-(Hydroxymethyl)piperidin-1-yl)pyrimidine-5-carboxylate Ethyl 2-(4-hydroxypiperidin-1-yl)pyrimidine-5-carboxylate 2-(4-Methylpiperazin-1-yl)pyrimidin-5-amine N,O-Bis(trimethylsilyl)acetamide Ethyl 2-(4-(ethoxycarbonyl)piperidin-1-yl)pyrimidine-5-carboxylate

(2-(4-Methylpiperazin-1-yl)pyrimidin-5-yl)methanol 2-Chloropyrimidine-5-carboxylic acid 2-(4-Hydroxypiperidin-1-yl)pyrimidine-5-carboxylic acid Ethyl 2-(4-(hydroxymethyl)piperidin-1-yl)pyrimidine-5-carboxylate Triazophos

Atracurium besylate 2-(4-Hydroxypiperidin-1-yl)pyrimidine-5-carboxamide (2-(4-Methylpiperazin-1-yl)pyrimidin-5-yl)methanamine

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Triethylamine hydrochloride Suppliers

Global( 564)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Weibang Biotechnology Co., Ltd	+8615531157085	abby@weibangbio.com	China	8810	58
Hebei Mojin Biotechnology Co., Ltd	+86 13288715578 +8613288715578	sales@hbmojin.com	China	12837	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	sales1@chuanghaibio.com	China	5889	58
Hebei Kingfiner Technology Development Co.Ltd	+86-15532196582 +86-15373005021	lisa@kingfinertech.com	China	3010	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20285	58
airuikechemical co., ltd.	+undefined86-15315557071	sales02@sdzhonghuimaterial.com	China	983	58
Hebei Mojin Biotechnology Co.,Ltd	+86-15028179902	angelia@hbmojin.com	China	1177	58
Hebei Zhuanglai Chemical Trading Co Ltd	+86-16264648883 +86-16264648883	niki@zlchemi.com	China	2397	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21634	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29880	58

Supplier	Advantage
Hebei Weibang Biotechnology Co., Ltd	58
Hebei Mojin Biotechnology Co., Ltd	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Hebei Kingfiner Technology Development Co.Ltd	58
Henan Fengda Chemical Co., Ltd	58
airuikechemical co., ltd.	58
Hebei Mojin Biotechnology Co.,Ltd	58
Hebei Zhuanglai Chemical Trading Co Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58

View Lastest Price from Triethylamine hydrochloride manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-12-18	Triethylamine Hydrochloride 554-68-7	US $79.00-38.00 / kg	1kg	99%	20ton	Hebei Zhuanglai Chemical Trading Co Ltd
2024-12-13	Triethylamine hydrochloride 554-68-7	US $0.00 / Kg/Drum	1KG	99%min	20 tons	WUHAN FORTUNA CHEMICAL CO., LTD
2024-11-12	Triethylamine hydrochloride 554-68-7	US $1.00 / KG	1KG	99%	10 mt	Hebei Weibang Biotechnology Co., Ltd

Triethylamine Hydrochloride
554-68-7
US $79.00-38.00 / kg
99%
Hebei Zhuanglai Chemical Trading Co Ltd

Triethylamine hydrochloride
554-68-7
US $0.00 / Kg/Drum
99%min
WUHAN FORTUNA CHEMICAL CO., LTD

Triethylamine hydrochloride
554-68-7
US $1.00 / KG
99%
Hebei Weibang Biotechnology Co., Ltd

Triethylamine hydrochloride Spectrum

Triethylamine hydrochloride(554-68-7)¹HNMR Triethylamine hydrochloride(554-68-7)¹³CNMR Triethylamine hydrochloride(554-68-7)IR1 Triethylamine hydrochloride(554-68-7)IR2 Triethylamine hydrochloride(554-68-7)Raman

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