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ALPHA-CYANO-4-HYDROXYCINNAMIC ACID

ALPHA-CYANO-4-HYDROXYCINNAMIC ACID structure

CAS No.: 28166-41-8

Chemical Name:: ALPHA-CYANO-4-HYDROXYCINNAMIC ACID

Synonyms: α-Cyano-4-hydroxycinnamic Acid;ACCA;α-CHCA;A-CYANO-4-HYDROXYCINNAMIC ACID;α-CCA;4-HCCA;α-CHCA;α-Cyano;ALPHA-CCA;ALPHA-CHCA

CBNumber:: CB0781327

Molecular Formula:: C10H7NO3

Molecular Weight:: 189.17

MDL Number:: MFCD00004204

MOL File:: 28166-41-8.mol

MSDS File:: SDS

Last updated:2024-04-28 15:15:04

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ALPHA-CYANO-4-HYDROXYCINNAMIC ACID Properties

Melting point	245-250 °C(lit.)
Boiling point	324.41°C (rough estimate)
Density	1.3175 (rough estimate)
refractive index	1.5400 (estimate)
storage temp.	2-8°C
solubility	methanol: 10 mg/mL, clear
form	powder
pka	0.85±0.10(Predicted)
color	yellow
BRN	3271427
InChIKey	AFVLVVWMAFSXCK-VMPITWQZSA-N
CAS DataBase Reference	28166-41-8(CAS DataBase Reference)
FDA UNII	NL5EEM9E2G

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H317-H319-H335

Precautionary statements

P280-P302+P352-P305+P351+P338

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36

WGK Germany

10-23

HS Code

29269090

NFPA 704

	0
2		0

ALPHA-CYANO-4-HYDROXYCINNAMIC ACID price More Price(46)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	70990	α-Cyano-4-hydroxycinnamic acid matrixsubstanceforMALDI-MS,≥99.0%(HPLC)	28166-41-8	250mg	$42.8	2024-03-01	Buy
Sigma-Aldrich	70990	α-Cyano-4-hydroxycinnamic acid matrixsubstanceforMALDI-MS,≥99.0%(HPLC)	28166-41-8	1g	$118	2024-03-01	Buy
Sigma-Aldrich	145505	α-Cyano-4-hydroxycinnamic acid 97%	28166-41-8	5g	$73.9	2024-03-01	Buy
Sigma-Aldrich	39468	α-Cyano-4-hydroxycinnamic acid matrixsubstanceforMALDI-MS,Ultrapure	28166-41-8	10x10mg	$332	2024-03-01	Buy
Sigma-Aldrich	145505	α-Cyano-4-hydroxycinnamic acid 97%	28166-41-8	25g	$97.2	2024-03-01	Buy

Product number	Packaging	Price	Buy
70990	250mg	$42.8	Buy
70990	1g	$118	Buy
145505	5g	$73.9	Buy
39468	10x10mg	$332	Buy
145505	25g	$97.2	Buy

ALPHA-CYANO-4-HYDROXYCINNAMIC ACID Chemical Properties,Uses,Production

Chemical Properties

yellow crystalline powder

Uses

α-Cyano-4-hydroxycinnamic acid(CHC) was used as a matrix for peptides and nucleotides in mass spectroscopic analysis. It was used in encapsulation of CHC into NaY zeolite. It was used as matrix to investigate the activity of the paclitaxel derivatives using several well-established in vitro angiogenesis assays.

Uses

inhibitor of mitochondrial pyruvate transport

Uses

α-Cyano-4-hydroxycinnamic acid (CHC) was used in encapsulation of CHC into NaY zeolite. It was used as matrix to investigate the activity of the paclitaxel derivatives using several well-established in vitro angiogenesis assays.

Definition

ChEBI: Alpha-cyano-4-hydroxycinnamic acid is a monohydroxycinnamic acid that is 4-hydroxycinnamic acid in which the hydrogen alpha- to the carboxy group is replaced by a cyano group. It is used as a matrix in matrix-assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of peptides and oligonucleotides. It has a role as a MALDI matrix material. It is a nitrile, a member of phenols and a monohydroxycinnamic acid.

General Description

α-Cyano-4-hydroxycinnamic acid is the commonly used matrix for analyzing peptides by matrix-assisted laser desorption/ionization mass spectrometry. It inhibits the monophenolase activity and diphenolase activity of mushroom tyrosinase.

Biochem/physiol Actions

α-Cyano-4-hydroxycinnamic acid acts as a specific inhibitor of monocarboxylic acid transport, including lactate and pyruvate transport. It is also reported to block β-cell apical anion exchange (IC50 of 2.4 mM).

storage

Store at +4°C

ALPHA-CYANO-4-HYDROXYCINNAMIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

ALPHA-CYANO-4-HYDROXYCINNAMIC ACID Suppliers

Global( 160)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Qyubiotech Co., Ltd.	+86-086-021-37596619 +8618019359838	info@qyubiotech.com	China	300	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20284	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	18751	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29880	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39894	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49374	58
Neostar United (Changzhou) Industrial Co., Ltd.	+86-0519-85551759 +8613506123987	marketing1@neostarunited.com	China	8838	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
Dayang Chem (Hangzhou) Co.,Ltd.	571-88938639 +8617705817739	info@dycnchem.com	China	52849	58

Supplier	Advantage
Shanghai Qyubiotech Co., Ltd.	58
Henan Fengda Chemical Co., Ltd	58
Shanghai Daken Advanced Materials Co.,Ltd	58
career henan chemical co	58
Hubei xin bonus chemical co. LTD	58
Chongqing Chemdad Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
Neostar United (Changzhou) Industrial Co., Ltd.	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Dayang Chem (Hangzhou) Co.,Ltd.	58

View Lastest Price from ALPHA-CYANO-4-HYDROXYCINNAMIC ACID manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-12-23	a-Cyano-4-hydroxycinnamic acid 28166-41-8	US $0.00-0.00 / kg	1kg	98%+	100000kg per Month	Shanghai Qyubiotech Co., Ltd.
2024-04-28	ALPHA-CYANO-4-HYDROXYCINNAMIC ACID 28166-41-8	US $10.00-2.00 / KG	1KG	99%	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd
2021-08-12	ALPHA-CYANO-4-HYDROXYCINNAMIC ACID 28166-41-8	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd

a-Cyano-4-hydroxycinnamic acid
28166-41-8
US $0.00-0.00 / kg
98%+
Shanghai Qyubiotech Co., Ltd.

ALPHA-CYANO-4-HYDROXYCINNAMIC ACID
28166-41-8
US $10.00-2.00 / KG
99%
Henan Fengda Chemical Co., Ltd

ALPHA-CYANO-4-HYDROXYCINNAMIC ACID
28166-41-8
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

ALPHA-CYANO-4-HYDROXYCINNAMIC ACID Spectrum

ALPHA-CYANO-4-HYDROXYCINNAMIC ACID(28166-41-8)MS ALPHA-CYANO-4-HYDROXYCINNAMIC ACID(28166-41-8)¹HNMR ALPHA-CYANO-4-HYDROXYCINNAMIC ACID(28166-41-8)¹³CNMR ALPHA-CYANO-4-HYDROXYCINNAMIC ACID(28166-41-8)IR1 ALPHA-CYANO-4-HYDROXYCINNAMIC ACID(28166-41-8)IR2 ALPHA-CYANO-4-HYDROXYCINNAMIC ACID(28166-41-8)Raman

28166-41-8(ALPHA-CYANO-4-HYDROXYCINNAMIC ACID)Related Search:

ALPHA-CYANO-4-HYDROXYCINNAMIC ACID CDC ALPHA-CYANO-4-METHOXYCINNAMIC ACID 1-BENZYL-4-CYANO-4-HYDROXYPIPERIDINE 4'-Hydroxy-4-biphenylcarbonitrile

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1of4

4-HCCA ALPHA-CCA ALPHA-CHCA ALPHA-CYANO ALPHA-CYANO-4-HYDROXYCINNAMIC ACID LABOTEST-BB LT00159295 ALPHA-CYANO-4-HYDROXYCINNAMIC ACID, USE ALPHA-CYANO-4-HYDROXYCINNAMIC ACID PGE.WITH 10 X 25 MG alpha-cyano-4-hydroxycinnamate 2-CYANO-3-(4-HYDROXYPHENYL)ACRYLIC ACID α-CCA, α-CHCA, α-Cyano, 4-HCCA, ACCA 2-Cyano-3-(4-hydroxyphenyl)propenoic acid α-Cyano-4-hydroxybenzenepropenoic acid alpha-Cyano-4-hydroxycinnamic acid,97% 2-Cyano-3-(4-hydroxyphenyl)acrylic Acid alpha-CHCA (E)-2-cyano-3-(4-hydroxyphenyl)acrylic acid alpha-Cyano-4-hydroxycinnaMic acid 99% 2-Propenoic acid,2-cyano-3-(4-hydroxyphenyl)- 2-cyano-3-(4-hydroxyphenyl)prop-2-enoic acid α-cyano-4-hydroxycinnamic acid(α-CHCA) 2-Cyano-3-(4-hydroxyphenyl)-2-propenoic acid alpha-Cyano-4-hydroxycinnamic acid 28166-41-8 alpha-Cyano-4-hydroxycinnamic acid PRICE α-Cyano-4-hydroxycinnamic Acid > α-cyano-4-hydroxycinnamicaci α-CCA α-Cyano alpha-Cyano-4-hydroxycinnamic acid, Ultrapure MALDI Matrix, A-CYANO-4-HYDROXYCINNAMIC ACID ACCA α-CHCA α-Cyano-4-hydroxycinnamic Acid α-Cyano-4-hydroxycinnamic acid(α-CHCA) α-CHCA 2-cyano-3-(4-hydroxyphenyl)prop-2-enoic acid (E)-2-cyano-3-(4-hydroxyphenyl)prop-2-enoic acid 28166-41-8 HOC6H4CHCCNCO2H CARBOXYLIC ACID Proteomics and Protein Expression Protein Analysis Matrices for MALDI Analysis Organic Building Blocks Matrix Materials (MALDI-TOF-MS) Mass Spectrometry Building Blocks Analytical Reagents Analytical Chromatography Product Catalog BioChemical Chiral C10 Carboxylic Acids Carbonyl Compounds UltraPure MALDI Matrices Analytical Chemistry Mass Spectrometry Matrix Materials (MALDI-TOF-MS)