L-Phenylalanine, N-[(2S)-2-hydroxy-1-oxopropyl]-
![L-Phenylalanine, N-[(2S)-2-hydroxy-1-oxopropyl]- Structure](CAS/20200611/GIF/183241-73-8.gif)
- CAS No.
- 183241-73-8
- Chemical Name:
- L-Phenylalanine, N-[(2S)-2-hydroxy-1-oxopropyl]-
- Synonyms
- N-Lactoyl-Phenylalanine;Lac-Phe-OH;Lac-Phe New;Lac-Phe . acetate;Lactoyl Phenylalanine;N-Lactoylphenylalanine;((S)-2-Hydroxypropanoyl)-L-phe-OH;((S)-2-Hydroxypropanoyl)-L-phenylalanine;N-[(S)-2-Hydroxypropanoyl]-L-phenylalanine;N-[(2S)-2-Hydroxy-1-oxopropyl]-L-phenylalanine
- CBNumber:
- CB08083292
- Molecular Formula:
- C12H15NO4
- Molecular Weight:
- 237.25
- MDL Number:
- MOL File:
- 183241-73-8.mol
| Melting point | >120oC (dec.) |
|---|---|
| Boiling point | 505.1±50.0 °C(Predicted) |
| Density | 1.268±0.06 g/cm3(Predicted) |
| storage temp. | -20°C Freezer, Under inert atmosphere |
| solubility | DMSO (Slightly), Methanol (Sparingly, Sonicated) |
| form | Solid |
| pka | 3.56±0.10(Predicted) |
| color | White to Off-White |
| biological source | synthetic |
| UNSPSC Code | 12352209 |
| NACRES | NA.26 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H315-H318 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P305+P351+P338-P310-P321-P362+P364-P332+P313 | |||||||||
| NFPA 704 |
|
L-Phenylalanine, N-[(2S)-2-hydroxy-1-oxopropyl]- Chemical Properties,Uses,Production
Uses
N-Lactoyl-Phenylalanine is a useful intermediate in the preparation of chiral morpholinediones by aminolysis of α-hydroxy esters with α-amino acid salts.
Definition
ChEBI: N-[(S)-lactoyl]-L-phenylalanine is a L-phenylalanine derivative that is L-phenylalanine in which the amino group is replaced by a [(2S)-2-hydroxypropanoyl]amino group. It is a metabolite produced as a result of exercise in mice, racehorses, and humans which suppresses feeding and obesity. It has a role as a human metabolite, a mouse metabolite, a mammalian metabolite and an anti-obesity agent. It is a L-phenylalanine derivative and a N-acyl-L-amino acid. It is a conjugate acid of a N-[(S)-lactoyl]-L-phenylalaninate.
in vivo
N-Lactoyl-Phenylalanine (50 mg/kg, i.p.,once a day for 10 days) specifically suppresses energy intake in obese mice without affecting energy expenditure pathways, and this effect is not observed in lean mice[1].
| Animal Model: | Diet-induced obese (DIO) mice model[1] |
| Dosage: | 50 mg/kg |
| Administration: | Intraperitoneal (i.p.), once a day for 10 days |
| Result: | Resulted in reduced cumulative food intake and reduced body weight compared with control mice. After 10?days, mice treated with N-Lactoyl-Phenylalanine also exhibited improved glucose homeostasis, and reduced adiposity without any changes in the weights of the other organs. |
storage
Room temperature
L-Phenylalanine, N-[(2S)-2-hydroxy-1-oxopropyl]- Preparation Products And Raw materials
Raw materials
Preparation Products
L-Phenylalanine, N-[(2S)-2-hydroxy-1-oxopropyl]- Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3135 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43340 | 58 |
| Cellmano Biotech Limited | 0551-65326643 18156095617 | info@cellmano.com | China | 1011 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9803 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71829 | 60 |
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 | Eric@peptidego.com | China | 7062 | 58 |
| Changzhou Xuanming Pharmaceutical Technology Co., Ltd. | 15995069468 | 29526743@qq.com | China | 278 | 58 |
| Binhai gill polypeptide co. LTD | 021-61263389 13524856427 | Joetang@glschina.com | China | 9662 | 58 |
| ShangHai Anpel Co, Ltd. | 18017382783 18017382783 | shanpel@anpel.com.cn | China | 9611 | 58 |
View Lastest Price from L-Phenylalanine, N-[(2S)-2-hydroxy-1-oxopropyl]- manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-19 | N-Lactoyl-Phenylalanine
183241-73-8
|
US $35.00-116.00 / mg | 98.95% | 10g | TargetMol Chemicals Inc. |
-
- N-Lactoyl-Phenylalanine
183241-73-8
- US $35.00-116.00 / mg
- 98.95%
- TargetMol Chemicals Inc.