Halobetasol Propionate 9-Chloro 21-Hydroxy Analog

Halobetasol Propionate 9-Chloro 21-Hydroxy Analog structure

CAS No.: 84509-91-1

Chemical Name:: Halobetasol Propionate 9-Chloro 21-Hydroxy Analog

Synonyms: Diflorasone 17-Propionate 9-Chloro;Halobetasol Propionate 9-Chloro 21-Hydroxy Analog;Pregna-1,4-diene-3,20-dione, 9-chloro-6-fluoro-11,21-dihydroxy-16-methyl-17-(1-oxopropoxy)-, (6α,11β,16β)- (9CI);(6α,?11β,?16β)?-9-?Chloro-?6-?fluoro-?11,?21-?dihydroxy-?16-?methyl-?17-?(1-?oxopropoxy)?-pregna-?1,?4-?diene-?3,?20-?dione

CBNumber:: CB08207436

Molecular Formula:: C25H32ClFO6

Molecular Weight:: 482.97

MDL Number:

MOL File:: 84509-91-1.mol

Last updated:2023-04-23 13:52:06

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Halobetasol Propionate 9-Chloro 21-Hydroxy Analog Properties

Boiling point	610.5±55.0 °C(Predicted)
Density	1.33±0.1 g/cm3(Predicted)
pka	12.71±0.70(Predicted)
form	Solid
color	Pale Orange

Halobetasol Propionate 9-Chloro 21-Hydroxy Analog Chemical Properties,Uses,Production

Uses

(6α,?11β,?16β)?-9-?Chloro-?6-?fluoro-?11,?21-?dihydroxy-?16-?methyl-?17-?(1-?oxopropoxy)?-pregna-?1,?4-?diene-?3,?20-?dione is an intermediate in synthesizing 9α-Chloro-9-desfluoro Halobetasol 17-Propionate (C368555). It is an impurity of Halobetasol Propionate (H102300); an anti-inflammatory and dermatologic agent commonly used to treat psoriasis.

Halobetasol Propionate 9-Chloro 21-Hydroxy Analog Preparation Products And Raw materials

Raw materials

Preparation Products

Diflorasone 17-Propionate 9-Chloro Halobetasol Propionate 9-Chloro 21-Hydroxy Analog Pregna-1,4-diene-3,20-dione, 9-chloro-6-fluoro-11,21-dihydroxy-16-methyl-17-(1-oxopropoxy)-, (6α,11β,16β)- (9CI) (6α,?11β,?16β)?-9-?Chloro-?6-?fluoro-?11,?21-?dihydroxy-?16-?methyl-?17-?(1-?oxopropoxy)?-pregna-?1,?4-?diene-?3,?20-?dione 84509-91-1 C25H32ClFO6