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ChemicalBook >> CAS DataBase List >>Acetic acid, 2-[[1-(2-chloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl]oxy]-

Acetic acid, 2-[[1-(2-chloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl]oxy]-

Acetic acid, 2-[[1-(2-chloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl]oxy]- Structure
Acetic acid, 2-[[1-(2-chloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl]oxy]- structure
CAS No.
2375196-30-6
Chemical Name:
Acetic acid, 2-[[1-(2-chloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl]oxy]-
Synonyms
KB02-COOH;2-((1-(2-Chloroacetyl)-1,2,3,4-tetrahydroquinolin-6-yl)oxy)acetic acid;Acetic acid, 2-[[1-(2-chloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl]oxy]-
CBNumber:
CB08382843
Molecular Formula:
C13H14ClNO4
Molecular Weight:
283.71
MDL Number:
MOL File:
2375196-30-6.mol
Last updated:2024-10-28 16:48:35
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Acetic acid, 2-[[1-(2-chloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl]oxy]- Properties

Boiling point 573.3±50.0 °C(Predicted)
Density 1.383±0.06 g/cm3(Predicted)
solubility DMSO: 66.67 mg/mL (234.99 mM)
form Solid
pka 3.20±0.10(Predicted)
color White to off-white

Acetic acid, 2-[[1-(2-chloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl]oxy]- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 925047 KB02-COOH 2375196-30-6 10MG $114 2023-06-20 Buy
Product number Packaging Price Buy
925047 10MG $114 Buy

Acetic acid, 2-[[1-(2-chloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl]oxy]- Chemical Properties,Uses,Production

Biological Activity

KB02-COOH is a fragment of synthesis of ubiquitin E3 ligase ligand KB02. KB02 can be used in the synthesis of PROTAC, such as KB02-JQ1 and KB02-SLF [1].

References

[1]. Zhang X, et al. Electrophilic PROTACs that degrade nuclear proteins by engaging DCAF16. Nat Chem Biol. 2019 Jul;15(7):737-746.

Acetic acid, 2-[[1-(2-chloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl]oxy]- Preparation Products And Raw materials

Raw materials

Preparation Products

Acetic acid, 2-[[1-(2-chloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl]oxy]- Suppliers

Global( 12)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		support@targetmol.com United States 38463 58
Daicel Chiral Technologies (China)CO.,LTD 021-50460086-9 15921403865 han_yajun@dctc.daicel.com China 7189 65
Chengdu Forest Science and Technology Development Co., Ltd. 18030648795 18030648795 sales@cdforestchem.com China 1578 58
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1387 58
Shanghai Haohong Pharmaceutical Co., Ltd. 4008210725 4008210725 malulu@leyan.com China 54986 58
Changzhou Bojia Biomedical Technology Co., Ltd. 2122619822 czbjpharma@126.com China 18478 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24648 58
Henan Alpha Chemical Co., Ltd. 0371-55013243 15324716602 2853979810@qq.com China 10036 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 13417589054 trendseenbio@gmail.com China 9470 58
Shanghai Easy CDMO Co.,Ltd 021-61734564 August@easycdmo.com China 10031 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Daicel Chiral Technologies (China)CO.,LTD 65
Chengdu Forest Science and Technology Development Co., Ltd. 58
Jilin Province Woda Biotechnology Co., Ltd. 58
Shanghai Haohong Pharmaceutical Co., Ltd. 58
Changzhou Bojia Biomedical Technology Co., Ltd. 58
TargetMol Chemicals Inc. 58
Henan Alpha Chemical Co., Ltd. 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 58
Shanghai Easy CDMO Co.,Ltd 58

View Lastest Price from Acetic acid, 2-[[1-(2-chloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl]oxy]- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
KB02-COOH pictures 2024-10-28 KB02-COOH
2375196-30-6
 US $297.00 / mg 10g TargetMol Chemicals Inc.
  • KB02-COOH pictures
  • KB02-COOH
    2375196-30-6
  • US $297.00 / mg
  • TargetMol Chemicals Inc.
Acetic acid, 2-[[1-(2-chloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl]oxy]- 2-((1-(2-Chloroacetyl)-1,2,3,4-tetrahydroquinolin-6-yl)oxy)acetic acid KB02-COOH 2375196-30-6