ChemicalBook >> CAS DataBase List >>Valganciclovir
Valganciclovir
- CAS No.
- 175865-60-8
- Chemical Name:
- Valganciclovir
- Synonyms
- Valgancyclovir;Valganciclov;valganciclovir;Valganciclovir-d8;Valganciclovir-d8 (Mixture of Diastereomers);Valganciclovir & Valganciclovir Hydrochloride;Valganciclovir-d5 HCl (Mixture of diastetroMers);L-Valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl ester;(2S)-2-((2-AMino-6-oxo-1H-purin-9(6H)-yl)Methoxy)-3-hydroxypropyl 2-aMino-3-Methylbutanoate;2-amino-3-methylbutanoic acid [2-[(2-amino-6-oxo-3H-purin-9-yl)methoxy]-3-hydroxypropyl] ester
- CBNumber:
- CB0855239
- Molecular Formula:
- C14H22N6O5
- Molecular Weight:
- 354.36
- MDL Number:
- MFCD05662329
- MOL File:
- 175865-60-8.mol
- MSDS File:
- SDS
Last updated:2024-11-19 20:33:22
| Density | 1.59±0.1 g/cm3(Predicted) |
|---|---|
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| pka | 9.32±0.20(Predicted) |
| BCS Class | 3 |
| InChI | InChI=1S/C14H22N6O5/c1-7(2)9(15)13(23)24-4-8(3-21)25-6-20-5-17-10-11(20)18-14(16)19-12(10)22/h5,7-9,21H,3-4,6,15H2,1-2H3,(H3,16,18,19,22)/t8?,9-/m0/s1 |
| InChIKey | WPVFJKSGQUFQAP-GKAPJAKFSA-N |
| SMILES | C(OCC(OCN1C2=C(N=C1)C(=O)NC(N)=N2)CO)(=O)[C@H](C(C)C)N |
| CAS DataBase Reference | 175865-60-8(CAS DataBase Reference) |
| NCI Dictionary of Cancer Terms | valganciclovir |
| FDA UNII | GCU97FKN3R |
| NCI Drug Dictionary | valganciclovir |
| ATC code | J05AB14 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Hazardous Substances Data | 175865-60-8(Hazardous Substances Data) |
Valganciclovir price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Medical Isotopes, Inc. | 33627 | Valganciclovir 98%purewithdatedHPLCUVchromatogram | 175865-60-8 | 1mg | $685 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0004848 | VALGANCICLOVIR 95.00% | 175865-60-8 | 0.25G | $764 | 2021-12-16 | Buy |
| Matrix Scientific | 097028 | (2S)-2-((2-Amino-6-oxo-1H-purin-9(6H)-yl)methoxy)-3-hydroxypropyl 2-amino-3-methylbutanoate 95+% | 175865-60-8 | 1g | $807 | 2021-12-16 | Buy |
| AK Scientific | Y0321 | Valganciclovir | 175865-60-8 | 1g | $1139 | 2021-12-16 | Buy |
| Matrix Scientific | 097028 | (2S)-2-((2-Amino-6-oxo-1H-purin-9(6H)-yl)methoxy)-3-hydroxypropyl 2-amino-3-methylbutanoate 95+% | 175865-60-8 | 250mg | $364 | 2021-12-16 | Buy |
Valganciclovir Chemical Properties,Uses,Production
Uses
Antiviral.
Uses
Valganciclovir-d8, is the labeled analogue of Valganciclovir (V092000), a pro-drug of Ganciclovir, used in treatment of retro-virus.
Definition
ChEBI: The L-valinyl ester of ganciclovir, into which it is rapidly converted by intestinal and hepatic esterases. It is a synthetic analogue of 2'-deoxyguanosine.
Indications
Valganciclovir (Valcyte) is the L-valyl ester prodrug of ganciclovir.
brand name
Valcyte (Roche).
Clinical Use
Oral valganciclovir is comparable to intravenous ganciclovir for the treatment and suppression of CMV retinitis in AIDS patients.
Drug interactions
Potentially hazardous interactions with other drugs
Antibacterials: increased risk of convulsions with
imipenem-cilastatin.
Antivirals: possibly increased didanosine
concentration; profound myelosuppression with
zidovudine - avoid if possible.
Mycophenolate: possibly increased concentrations of
both mycophenolic acid and ganciclovir.
Increased risk of myelosuppression with other
myelosuppressive drugs.
Metabolism
Valganciclovir is well absorbed from the gastrointestinal tract and rapidly and extensively metabolised in the intestinal wall and liver to ganciclovir. Valganciclovir is eliminated in the urine as unchanged ganciclovir, mainly by glomerular filtration and also active tubular secretion.
Valganciclovir Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 127)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| HangZhou RunYan Pharma Technology Co.,LTD. | +8618882027439 | sales2@runyanpharma.com | China | 302 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
| Shanghai Yingrui Biopharma Co., Ltd. | +86-21-33585366 - 03@ | sales03@shyrchem.com | CHINA | 738 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29880 | 58 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2930 | 58 |
| Beijing Yibai Biotechnology Co., Ltd | 0086-182-6772-3597 | sales04@yibaibiotech.com | CHINA | 419 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14426 | 58 |
View Lastest Price from Valganciclovir manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-12-22 | Valganciclovir
175865-60-8
|
US $0.00-0.00 / g | 10g | 99% HPLC | 10000 | HangZhou RunYan Pharma Technology Co.,LTD. | |
 |
2024-12-20 | Valganciclovir
175865-60-8
|
US $0.00 / Kg/Bag | 2Kg/Bag | 99% up, High Density | 20 tons | Sinoway Industrial co., ltd. | |
 |
2024-11-19 | Valganciclovir
175865-60-8
|
US $2500.00-1980.00 / mg | 10g | TargetMol Chemicals Inc. |
-
- Valganciclovir
175865-60-8
- US $0.00-0.00 / g
- 99% HPLC
- HangZhou RunYan Pharma Technology Co.,LTD.
-
- Valganciclovir
175865-60-8
- US $0.00 / Kg/Bag
- 99% up, High Density
- Sinoway Industrial co., ltd.
-
- Valganciclovir
175865-60-8
- US $2500.00-1980.00 / mg
- TargetMol Chemicals Inc.
175865-60-8(Valganciclovir)Related Search:
valganciclovir
Valganciclovir & Valganciclovir Hydrochloride
Valganciclovir-d8
(2S)-2-((2-AMino-6-oxo-1H-purin-9(6H)-yl)Methoxy)-3-hydroxypropyl 2-aMino-3-Methylbutanoate
5-amino-3-[1-(hydroxymethyl)-2-(l-valyloxy)ethoxymethyl]-6,7- dihydro-3h-imidazo[4,5-d]pyrimidin-7-one
Valganciclovir-d5 HCl (Mixture of diastetroMers)
Valganciclovir-d8 (Mixture of Diastereomers)
2-amino-3-methylbutanoic acid [2-[(2-amino-6-oxo-3H-purin-9-yl)methoxy]-3-hydroxypropyl] ester
Valganciclov
L-Valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl ester
ValganciclovirQ: What is
Valganciclovir Q: What is the CAS Number of
Valganciclovir Q: What is the storage condition of
Valganciclovir Q: What are the applications of
Valganciclovir
Valgancyclovir
175865-60-8
175680-60-8
C14H22N6O5
API