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beta-D-Fructopyranose

CAS No.
7660-25-5
Chemical Name:
beta-D-Fructopyranose
Synonyms
Fructopyranose;S(-)-FRUCTOSE;β-D-Fructopyranose;Frutabs;Levungen;Laevoral;Fructosteril;FRUCTOSE HPLC;Fructose powder;Fructose,HPLC≥96%
CBNumber:
CB0875684
Molecular Formula:
C6H12O6
Molecular Weight:
180.16
MDL Number:
MFCD00065409
MOL File:
7660-25-5.mol
Last updated:2025-04-30 13:36:08

beta-D-Fructopyranose Properties

Melting point 103°C
Boiling point 232.96°C (rough estimate)
Density 1.6000
refractive index 1.6170 (estimate)
pka 11.52±0.70(Predicted)
form Solid
color White to off-white
CAS DataBase Reference 7660-25-5
FDA UNII R73GS1TJE0
NIST Chemistry Reference Fructose(7660-25-5)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazardous Substances Data 7660-25-5(Hazardous Substances Data)

beta-D-Fructopyranose price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ApexBio Technology N1503 Fructose 7660-25-5 20mg $25 2021-12-16 Buy
ChemScene CS-8113 Fructose ≥98.0% 7660-25-5 500mg $50 2021-12-16 Buy
ChemScene CS-8113 Fructose ≥98.0% 7660-25-5 1g $60 2021-12-16 Buy
ChemScene CS-8113 Fructose ≥98.0% 7660-25-5 5g $84 2021-12-16 Buy
American Custom Chemicals Corporation CRB0000796 BETA-D-(-)-FRUCTOSE 95.00% 7660-25-5 100G $2457.88 2021-12-16 Buy
Product number Packaging Price Buy
N1503 20mg $25 Buy
CS-8113 500mg $50 Buy
CS-8113 1g $60 Buy
CS-8113 5g $84 Buy
CRB0000796 100G $2457.88 Buy

beta-D-Fructopyranose Chemical Properties,Uses,Production

Chemical Properties

Fructose is also called levulose or fruit sugar, C6H12O6. It is the sweetest of the common sugars, being from 1.1 to 2.0 times as sweet as sucrose. Fructose is generally found in fruits and honey. An apple is 4% sucrose, 6% fructose, and 1% glucose (by weight). A grape (Vitis labrusca) is about 2% sucrose, 8% fructose, 7% glucose, and 2% maltose (by weight) (Shallenberger).

Uses

Fructose is a simple ketonic monosaccharide found in many plants, where it is often bonded to glucose to form the disaccharide sucrose.

Production Methods

Commercially processed fructose is available as white crystals, soluble in water, alcohol, and ether, with a melting point between 103 and 105 °C (217.4 and 221 °F) (decomposition). Fructose can be derived by the hydrolysis of inulin; by the hydrolysis of beet sugar followed by lime separation; and from cornstarch by enzymic or microbial action.

Definition

ChEBI: Beta-D-fructopyranose is a D-fructopyranose in which the anomeric centre has beta-configuration. It is an enantiomer of a beta-L-fructopyranose.

in vivo

Fructose can be used in animal modeling to create rat models of hyperuricemia and diabetes. In mice fed a 0% Fructose diet, portal vein (0.060±0.006 mM, overall average across all time points) and systemic (0.030±0.003 mM) Fructose concentrations do not change over time after feeding. In contrast, in wild-type mice, the portal vein concentration more than doubles from time (t)=0 to t=1 hour post-feeding (~0.13 mM). Similarly, systemic serum Fructose increases from 0.037 at t=0 to 0.13 mM one hour post-feeding. In the 20% group, fasting (t=0) serum Fructose levels in the portal vein and systemically are similar to the postprandial concentrations in 0% mice, suggesting that baseline Fructose concentrations during fasting are not affected by diet. At the same dietary conditions, time, and sampling site, serum Fructose concentrations in KHK-/- mice are 5 to 100 times higher than in wild-type mice. The mean (across all time points) portal vein and systemic glucose concentrations in mice fed 20% Fructose are approximately 3 (P=0.004) and 2 (P=0.04) mM higher, respectively, compared to mice fed 0% Fructose. Systemic Fructose concentrations in KHK-/- mice fed 20% Fructose are about three times higher than in mice fed glucose, whereas systemic Fructose concentrations in wild-type mice fed Fructose are similar to those fed glucose[2].

Induces high uric acid[3]
Background
Fructose accelerates the synthesis of purines, increases the production of uric acid, reduces the excretion of uric acid by affecting kidney function, and also produces a large amount of reactive oxygen species, leading to oxidative stress, activating inflammatory signaling pathways and promoting uric acid production.
Specific Modeling Methods
Mice: ICR male mice ? 18-22 g
Administration: 30% Fructose in drinking water ? intragastrically ? for six weeks
Note
(1) Mice were placed in a temperature and humidity controlled environment with a 12 h light-dark cycle[3].
(2) Fresh drinking water was replaced every 2 days[3].
(3) 24 h urine volume was collected and recorded[3].
Modeling Indicators
Molecular changes: mouse renal urate transporter 1 (URAT1), glucose transporter 9 (GLUT9) increased protein levels, ATP-binding cassette subfamily G member 2 (ABCG2) and organic anion transporter 1 (OAT1) decreased protein levels, and organic cation transporter 1 (OCT1) and OCT2 were downregulated. Increases protein levels of TLR4 and MyD88 in the kidneys. NLRP3 inflammasome is activated and IL-1β secretion is increased[3].
Tissue changes: Infiltration of inflammatory cells in mouse glomeruli[3].
Metabolic changes: Increase serum uric acid, creatinine, blood urea nitrogen levels, reduce urine uric acid and creatinine levels (FEUA is significantly reduced)[3].
Correlated Product(s): /
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Induces type 2 diabetes[4]
Background
Fructose's metabolites induce insulin resistance, and the reactive oxygen species produced lead to oxidative stress, activate inflammatory responses and affect the action of insulin. Fructose is rapidly metabolized in the liver, resulting in excess production, leading to obesity and hyperlipidemia.
Specific Modeling Methods
Rat: Male Sprague Dawley rats ? 200-250 g
Administration: 65% fructose ? oral administration ? 8 weeks of feeding
Note
(1) At 3 and 8 weeks, blood was collected from the retroorbital plexus using small capillary tubes and serum was collected for biochemical analysis[4].
Modeling Indicators
Molecular changes: Serum glucose, insulin, triglyceride, uric acid levels and insulin resistance were significantly increased. TBARS in liver tissue increased and GSH levels decreased[4].
Correlated Product(s): /
Opposite Product(s): /

References

[1] Cirillo P, et al. Fructose induces prothrombotic phenotype in human endothelial cells : A new role for "added sugar" in cardio-metabolic risk. J Thromb Thrombolysis. 2015 Nov;40(4):444-51. DOI:10.1007/s11239-015-1243-1
[2] Patel C, et al. Effect of dietary fructose on portal and systemic serum fructose levels in rats and in KHK-/- and GLUT5-/- mice. Am J Physiol Gastrointest Liver Physiol. 2015 Nov 1;309(9):G779-90. DOI:10.1152/ajpgi.00188.2015
[3] Ying Yang, et al. Wuling San protects kidney dysfunction by inhibiting renal TLR4/MyD88 signaling and NLRP3 inflammasome activation in high fructose-induced hyperuricemic mice. J Ethnopharmacol. 2015 Jul 1:169:49-59. DOI:10.1016/j.jep.2015.04.011
[4] Raju Padiya, et al. Garlic improves insulin sensitivity and associated metabolic syndromes in fructose fed rats. Nutr Metab (Lond). 2011 Jul 27:8:53. DOI:10.1186/1743-7075-8-53

beta-D-Fructopyranose Preparation Products And Raw materials

Global( 256)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mujin Biotechnology Co.,Ltd
+86 13288715578 +8613288715578 sales@hbmojin.com China 12798 58
Hebei Chuanghai Biotechnology Co., Ltd
+8615531151365 mina@chuanghaibio.com China 18137 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21628 55
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29857 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28172 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19552 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49732 58
Neostar United (Changzhou) Industrial Co., Ltd.
+86-0519-85551759 +8613506123987 marketing1@neostarunited.com China 8831 58
Hebei Yanxi Chemical Co., Ltd.
+8617531153977 allison@yan-xi.com China 5854 58
Wuhan ChemNorm Biotech Co.,Ltd.
+86-27-8439 4403 18971486879 sales@chemnorm.com CHINA 2935 58

View Lastest Price from beta-D-Fructopyranose manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Fructose pictures 2025-04-30 Fructose
7660-25-5
US $48.00 / g 99.83% 10g TargetMol Chemicals Inc.
beta-D-Fructopyranose pictures 2025-04-30 beta-D-Fructopyranose
7660-25-5
US $0.00 / G 10G 98%min 30kg/month WUHAN FORTUNA CHEMICAL CO., LTD
beta-D-Fructopyranose pictures 2025-04-15 beta-D-Fructopyranose
7660-25-5
US $0.00-0.00 / KG 1KG 99% 500000kg Hebei Chuanghai Biotechnology Co., Ltd
  • Fructose pictures
  • Fructose
    7660-25-5
  • US $48.00 / g
  • 99.83%
  • TargetMol Chemicals Inc.
beta-D-fructopyranose FRUCTOSE HPLC Fructosteril Frutabs Laevoral Levungen (2R,3S,4R,5R)-2-methyloltetrahydropyran-2,3,4,5-tetrol FRUCTOPYRANOSE,BETA-D- (2R,3S,4R,5R)-2-(Hydroxymethyl)oxane-2,3,4,5-tetrol Engelite net impurities 25 Empagliflozin impurity 69 Fructose,HPLC≥96% beta-D-Fructopyranose USP/EP/BP 2-(hydroxymethyl) tetrahydro-2H-pyran-2,3,4,5-tetraol BRL 15573 dihydrochloride Fructopyranose S(-)-FRUCTOSE β-D-Fructopyranose D-FRUCTOSE(5-D, 95-98%) Fructose powder (2R,3S,4R,5R)-2-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol Fructose, 10 mM in DMSO 7660-25-5 chemical reagent pharmaceutical intermediate phytochemical Inhibitors reference standards from Chinese medicinal herbs (TCM). standardized herbal extract