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CYD19

CYD19 Structure
CYD19 structure
CAS No.
2415281-52-4
Chemical Name:
CYD19
Synonyms
CYD19;Snail/HDAC-IN-1;Benzamide, N-(2-amino-4-fluorophenyl)-4-[[[4-[(5-methyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]thio]methyl]-
CBNumber:
CB09321676
Molecular Formula:
C24H21FN8OS
Molecular Weight:
488.54
MDL Number:
MOL File:
2415281-52-4.mol
Last updated:2025-04-18 09:51:33
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CYD19 Properties

Density 1.50±0.1 g/cm3(Predicted)
pka 11.92±0.70(Predicted)
form Solid
color Light yellow to light brown

CYD19 Chemical Properties,Uses,Production

Uses

CYD19 is a potent Snail/HDAC dual target inhibitor. CYD19 displays potent inhibitory activity against HDAC1 with an IC50 of 0.405 μM and potent inhibition against Snail with a Kd of 0.18 μM. CYD19 increases histone H4 acetylation in HCT-116 cells and decreases the expression of Snail protein to induce cell apoptosis[1].

IC 50

HDAC1: 0.405 μM (IC50); Snail: 0.18 μM (Kd)

References

[1] Cui H, et al. Design and synthesis of dual inhibitors targeting snail and histone deacetylase for the treatment of solid tumour cancer. Eur J Med Chem. 2022;229:114082. DOI:10.1016/j.ejmech.2021.114082

CYD19 Preparation Products And Raw materials

Raw materials

Preparation Products

CYD19 Suppliers

Global( 16)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32159 58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd 		+86-18341751992 +86-15382112998 757984502@qq.com China 892 58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		+8613720134139 orders@jknbiochem.com China 5221 58
ShangHai Biochempartner Co.,Ltd 17754423994 17754423994 2853530910@QQ.com China 8011 62
DC Chemicals 021-58447131 13564518121 sales@dcchemicals.com China 9409 58
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd 15317229551 15151849396@163.com China 998 58
ShangHai ChuanQian Chemcial Technique Centre 15869524721 3525679403@qq.com China 4347 58
cjbscvictory 13348960310 13348960310 3003867561@qq.com China 10524 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24641 58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd 024-024-024-88590548 18341751992 757984502@qq.com China 930 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd 		58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		58
ShangHai Biochempartner Co.,Ltd 62
DC Chemicals 58
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd 58
ShangHai ChuanQian Chemcial Technique Centre 58
cjbscvictory 58
TargetMol Chemicals Inc. 58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd 58

View Lastest Price from CYD19 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Snail/HDAC-IN-1 pictures 2024-11-19 Snail/HDAC-IN-1
2415281-52-4
 US $455.00-655.00 / mg 97% 10g TargetMol Chemicals Inc.
  • Snail/HDAC-IN-1 pictures
  • Snail/HDAC-IN-1
    2415281-52-4
  • US $455.00-655.00 / mg
  • 97%
  • TargetMol Chemicals Inc.
CYD19 Snail/HDAC-IN-1 Benzamide, N-(2-amino-4-fluorophenyl)-4-[[[4-[(5-methyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]thio]methyl]- 2415281-52-4