Defluoro O-Methyl Dolutegravir
- CAS No.
- 2244245-33-6
- Chemical Name:
- Defluoro O-Methyl Dolutegravir
- Synonyms
- Defluoro O-Methyl Dolutegravir;(4R,12aS)-N-(4-fluorobenzyl)-7-methoxy-4-methyl-6,8-dioxo-3,4,6, 8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine9-carboxamide;2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(4-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-methoxy-4-methyl-6,8-dioxo-, (4R,12aS)-
- CBNumber:
- CB09401361
- Molecular Formula:
- C21H22FN3O5
- Molecular Weight:
- 415.41
- MDL Number:
- MOL File:
- 2244245-33-6.mol
Defluoro O-Methyl Dolutegravir Chemical Properties,Uses,Production
Uses
Defluoro O-Methyl Dolutegravir is an intermediate in the synthesis of Defluoro Dolutegravir (D228715) which is an impurity of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.
Defluoro O-Methyl Dolutegravir Preparation Products And Raw materials
Raw materials
Preparation Products
Defluoro O-Methyl Dolutegravir Suppliers
Global( 2)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Beijing Comparison Pharmaceutical Technology Co., Ltd | 010-010-52878169 15801002657 | sales@bjcomparison.com | China | 4937 | 58 |
| Wuxi Helen Biotechnology Co., Ltd., | 0510-85629785 18013409632 | sales@reading-chemicals.com | China | 14081 | 58 |
| Supplier | Advantage |
|---|---|
| Beijing Comparison Pharmaceutical Technology Co., Ltd | 58 |
| Wuxi Helen Biotechnology Co., Ltd., | 58 |
Defluoro O-Methyl Dolutegravir
2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(4-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-methoxy-4-methyl-6,8-dioxo-, (4R,12aS)-
(4R,12aS)-N-(4-fluorobenzyl)-7-methoxy-4-methyl-6,8-dioxo-3,4,6, 8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine9-carboxamide
2244245-33-6