ChemicalBook >> CAS DataBase List >>IACS-8803 disodium

IACS-8803 disodium

CAS No.
2243079-36-7
Chemical Name:
IACS-8803 disodium
Synonyms
IACS-8803 disodium
CBNumber:
CB09624124
Molecular Formula:
C20H24FN10NaO9P2S2
Molecular Weight:
716.53
MDL Number:
MOL File:
2243079-36-7.mol
Last updated:2024-07-02 08:54:58

IACS-8803 disodium Properties

storage temp. Store at -20°C, stored under nitrogen
form Solid
color White to off-white
Water Solubility Water : 56.67 mg/mL (76.74 mM; Need ultrasonic)

IACS-8803 disodium Chemical Properties,Uses,Production

Biological Activity

IACS-8803 disodium is a highly potent cyclic dinucleotide STING agonist. IACS-8803 disodium has a robust systemic antitumor efficacy[1]. IACS-8803 (10 μg; intra-tumoral injection) shows superior antitumor activity in mice bearing bilateral B16-OVA melanomas[1].

References

[1]. Ager CR, et al. Discovery of IACS-8803 and IACS-8779, potent agonists of stimulator of interferon genes (STING) with robust systemic antitumor efficacy. Bioorg Med Chem Lett. 2019 Oct 15;29(20):126640.

IACS-8803 disodium Preparation Products And Raw materials

Raw materials

Preparation Products

IACS-8803 disodium Suppliers

Global( 4)Suppliers
Supplier Tel Email Country ProdList Advantage
Nantong HI-FUTURE Biology Co., Ltd.
+undefined18051384581 sales@chemhifuture.com China 3136 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696,15000506266 15000506266 China 4362 55
Shanghai Tachizaki Biomedical Research Center 18014399201 sales@chemlab-tachizaki.com China 2551 58
IACS-8803 disodium 2243079-36-7