ChemicalBook >> CAS DataBase List >>1H-Benzo[a]fluorene-7,9-diol, 2,3,4,4a,5,6,6a,11,11a,11b-decahydro-4,4,6a,11b-tetramethyl-, (4aS,6aR,11aR,11bS)-

1H-Benzo[a]fluorene-7,9-diol, 2,3,4,4a,5,6,6a,11,11a,11b-decahydro-4,4,6a,11b-tetramethyl-, (4aS,6aR,11aR,11bS)-

CAS No.
1000010-33-2
Chemical Name:
1H-Benzo[a]fluorene-7,9-diol, 2,3,4,4a,5,6,6a,11,11a,11b-decahydro-4,4,6a,11b-tetramethyl-, (4aS,6aR,11aR,11bS)-
Synonyms
AQXMN115;AQX MN115;AQX-MN115;AQXMN115,AQX-MN-115,AQX MN115;1H-Benzo[a]fluorene-7,9-diol, 2,3,4,4a,5,6,6a,11,11a,11b-decahydro-4,4,6a,11b-tetramethyl-, (4aS,6aR,11aR,11bS)-
CBNumber:
CB09804676
Molecular Formula:
C21H30O2
Molecular Weight:
314.46
MDL Number:
MOL File:
1000010-33-2.mol
Last updated:2025-04-17 18:22:24

1H-Benzo[a]fluorene-7,9-diol, 2,3,4,4a,5,6,6a,11,11a,11b-decahydro-4,4,6a,11b-tetramethyl-, (4aS,6aR,11aR,11bS)- Properties

Boiling point 440.3±25.0 °C(Predicted)
Density 1.094±0.06 g/cm3(Predicted)
pka 9.94±0.70(Predicted)

1H-Benzo[a]fluorene-7,9-diol, 2,3,4,4a,5,6,6a,11,11a,11b-decahydro-4,4,6a,11b-tetramethyl-, (4aS,6aR,11aR,11bS)- Chemical Properties,Uses,Production

Description

AQX-MN115 is a SH2-?containing inositol 5-?phosphatase (SHIP 1) modulator.

Uses

SHIP1 activator 1 is an SH3 domain-containing inositol 5-phosphatase regulator with SHIP1 activating activity. SHIP1 activator 1 retains its SHIA-1 activating ability by removing unnecessary functional groups. SHIP1 activator 1 is able to activate SHIP1 in vitro, inhibit Akt phosphorylation in MOLT-4 cells, and show dose-dependent activity in a mouse model of inflammation. SHIP1 activator 1 is an important chemical tool for evaluating the potential of SHIP1 activators as inhibitors of hematopoietic diseases involving abnormal PI3K cell signaling[1].

References

[1] Synthesis of SHIP1-Activating Analogs of the Sponge Meroterpenoid Pelorol

1H-Benzo[a]fluorene-7,9-diol, 2,3,4,4a,5,6,6a,11,11a,11b-decahydro-4,4,6a,11b-tetramethyl-, (4aS,6aR,11aR,11bS)- Preparation Products And Raw materials

Raw materials

Preparation Products

1H-Benzo[a]fluorene-7,9-diol, 2,3,4,4a,5,6,6a,11,11a,11b-decahydro-4,4,6a,11b-tetramethyl-, (4aS,6aR,11aR,11bS)- Suppliers

Global( 4)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+17819995354 marketing@targetmol.com United States 32301 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49734 58
TargetMol Chemicals Inc.
+17819995354 marketing@targetmol.com United States 19904 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 23248 58

View Lastest Price from 1H-Benzo[a]fluorene-7,9-diol, 2,3,4,4a,5,6,6a,11,11a,11b-decahydro-4,4,6a,11b-tetramethyl-, (4aS,6aR,11aR,11bS)- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
AQX-MN115 pictures 2024-10-28 AQX-MN115
1000010-33-2
US $2180.00-2800.00 / mg 10g TargetMol Chemicals Inc.
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  • AQX-MN115
    1000010-33-2
  • US $2180.00-2800.00 / mg
  • TargetMol Chemicals Inc.
1H-Benzo[a]fluorene-7,9-diol, 2,3,4,4a,5,6,6a,11,11a,11b-decahydro-4,4,6a,11b-tetramethyl-, (4aS,6aR,11aR,11bS)- AQX MN115 AQXMN115 AQX-MN115 AQXMN115,AQX-MN-115,AQX MN115 1000010-33-2