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INDEX NAME NOT YET ASSIGNED

INDEX NAME NOT YET ASSIGNED structure

CAS No.: 2563617-99-0

Chemical Name:: INDEX NAME NOT YET ASSIGNED

Synonyms: GS-441524 tris-isobutyryl ester

CBNumber:: CB110545570

Molecular Formula:: C24H31N5O7

Molecular Weight:: 501.54

MDL Number:

MOL File:: 2563617-99-0.mol

Last updated:2023-05-21 10:59:17

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INDEX NAME NOT YET ASSIGNED Properties

Density	1.37±0.1 g/cm3(Predicted)
storage temp.	-20°C
solubility	DMF: 10 mg/ml,DMSO: 10 mg/ml,DMSO:PBS (pH 7.2) (1:5): 0.16 mg/ml
form	A crystalline solid
pka	4.11±0.30(Predicted)

INDEX NAME NOT YET ASSIGNED Chemical Properties,Uses,Production

Biological Activity

GS-441524 tris-isobutyryl ester is a prodrug form of the antiviral nucleoside analog and remdesivir metabolite GS-441524 .1 It reduces the cytopathic effect of respiratory syncytial virus (RSV) in infected HEp-2 cells with an EC50 value of 0.26 μM.

References

1.Mackman, R.L., Hui, H.C., Perron, M., et al.Prodrugs of a 1’-CN-4-aza-7,9-dideazaadenosine C-nucleoside leading to the discovery of remdesivir (GS-5734) as a potent inhibitor of respiratory syncytial virus with efficacy in the african green monkey model of RSVJ. Med. Chem.64(8)5001-5017(2021)

INDEX NAME NOT YET ASSIGNED Preparation Products And Raw materials

Raw materials

Preparation Products

INDEX NAME NOT YET ASSIGNED Suppliers

Global( 3)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	11974	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	19711	58

Supplier	Advantage
Shanghai Yifei Biotechnology Co. , Ltd.	58
TargetMol Chemicals Inc.	58

GS-441524 tris-isobutyryl ester 2563617-99-0