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Xylopine

CAS No.
517-71-5
Chemical Name:
Xylopine
Synonyms
Xylopine;6Abeta-noraporphine, 9-methoxy-1,2-(methylenedioxy)-;(7aR)-6,7,7a,8-Tetrahydro-10-methoxy-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline;5H-Benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline, 6,7,7a,8-tetrahydro-10-methoxy-, (7aR)-
CBNumber:
CB11180085
Molecular Formula:
C18H17NO3
Molecular Weight:
295.33
MDL Number:
MOL File:
517-71-5.mol
Last updated:2025-04-17 18:22:24

Xylopine Properties

Melting point 78-102°C
storage temp. 4°C, away from moisture and light
form Solid
color Light yellow to yellow
FDA UNII NNZ7TH999H

Xylopine Chemical Properties,Uses,Production

Description

An alkaloid obtained from Xylopia discreta, this base belongs to the noraporphine class of bases. It crystallizes from Me2CO as colourless needles and has [α]25/sup>D - 23.4°C (MeOH). The crystalline hydrochloride has m.p. 250°C and the N-acetyl derivative, m.p. 213-4°C. One methoxyl group and one methylenedioxy group are present, the structure being that of O-methylanolobine.

Uses

Xylopine is an aporphine alkaloid with cytotoxic activity on cancer cells. Xylopine induces oxidative stress, causes G2/M cell cycle arrest and apoptosis in cancer cells[1].

Definition

ChEBI: Xylopine is an aporphine alkaloid.

References

Schmutz., Helv. Chim. Acta, 42, 335 (1959)

Xylopine Preparation Products And Raw materials

Raw materials

Preparation Products

Xylopine Suppliers

Global( 12)Suppliers
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Mensura Group Limited 18728485362 18109034517@163.com China 2898 58
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Chengdu Peter-like Biotechnology Co., Ltd. 028-81700200 13308200041 2851167782@qq.com China 11183 58
Xylopine (7aR)-6,7,7a,8-Tetrahydro-10-methoxy-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline 6Abeta-noraporphine, 9-methoxy-1,2-(methylenedioxy)- 5H-Benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline, 6,7,7a,8-tetrahydro-10-methoxy-, (7aR)- 517-71-5