Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>Cyclobutanecarboxylic acid, 3-[(3R)-3-[1-[5-chloro-4-[[(1R)-1-(2,4-dichlorophenyl)ethyl]amino]-6-methyl-2-pyrimidinyl]-3-azetidinyl]-1-piperidinyl]-1-methyl-, trans-

Cyclobutanecarboxylic acid, 3-[(3R)-3-[1-[5-chloro-4-[[(1R)-1-(2,4-dichlorophenyl)ethyl]amino]-6-methyl-2-pyrimidinyl]-3-azetidinyl]-1-piperidinyl]-1-methyl-, trans-

Cyclobutanecarboxylic acid, 3-[(3R)-3-[1-[5-chloro-4-[[(1R)-1-(2,4-dichlorophenyl)ethyl]amino]-6-methyl-2-pyrimidinyl]-3-azetidinyl]-1-piperidinyl]-1-methyl-, trans- Structure
Cyclobutanecarboxylic acid, 3-[(3R)-3-[1-[5-chloro-4-[[(1R)-1-(2,4-dichlorophenyl)ethyl]amino]-6-methyl-2-pyrimidinyl]-3-azetidinyl]-1-piperidinyl]-1-methyl-, trans- structure
CAS No.
2366152-15-8
Chemical Name:
Cyclobutanecarboxylic acid, 3-[(3R)-3-[1-[5-chloro-4-[[(1R)-1-(2,4-dichlorophenyl)ethyl]amino]-6-methyl-2-pyrimidinyl]-3-azetidinyl]-1-piperidinyl]-1-methyl-, trans-
Synonyms
RPT193;Zelnecirnon;Zelnecirnon (RPT193);Cyclobutanecarboxylic acid, 3-[(3R)-3-[1-[5-chloro-4-[[(1R)-1-(2,4-dichlorophenyl)ethyl]amino]-6-methyl-2-pyrimidinyl]-3-azetidinyl]-1-piperidinyl]-1-methyl-, trans-
CBNumber:
CB112124940
Molecular Formula:
C27H34Cl3N5O2
Molecular Weight:
566.95
MDL Number:
MOL File:
2366152-15-8.mol
Last updated:2024-07-02 08:54:59
Request For Quotation

Cyclobutanecarboxylic acid, 3-[(3R)-3-[1-[5-chloro-4-[[(1R)-1-(2,4-dichlorophenyl)ethyl]amino]-6-methyl-2-pyrimidinyl]-3-azetidinyl]-1-piperidinyl]-1-methyl-, trans- Properties

Boiling point 706.9±70.0 °C(Predicted)
Density 1.387±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
form Solid
pka 4.09±0.20(Predicted)
color White to off-white
FDA UNII Q0M1LOC2MM

Cyclobutanecarboxylic acid, 3-[(3R)-3-[1-[5-chloro-4-[[(1R)-1-(2,4-dichlorophenyl)ethyl]amino]-6-methyl-2-pyrimidinyl]-3-azetidinyl]-1-piperidinyl]-1-methyl-, trans- Chemical Properties,Uses,Production

Description

Zelnecirnon, also known as RPT193, is a CCR4 antagonist that blocks the recruitment of Th2 cells in order to treat inflammatory diseases (taken orally). The Phase 1b trial, which was conducted in patients with atopic dermatitis, found that markable improvement occurred after 4 weeks with little side effects. A Phase 2 clinical trial is currently being conducted to evaluate the efficacy and safety of Zelnecirnon, with an expected end date of September 2023.

Cyclobutanecarboxylic acid, 3-[(3R)-3-[1-[5-chloro-4-[[(1R)-1-(2,4-dichlorophenyl)ethyl]amino]-6-methyl-2-pyrimidinyl]-3-azetidinyl]-1-piperidinyl]-1-methyl-, trans- Preparation Products And Raw materials

Raw materials

Preparation Products

Cyclobutanecarboxylic acid, 3-[(3R)-3-[1-[5-chloro-4-[[(1R)-1-(2,4-dichlorophenyl)ethyl]amino]-6-methyl-2-pyrimidinyl]-3-azetidinyl]-1-piperidinyl]-1-methyl-, trans- Suppliers

Global( 6)Suppliers
Supplier Tel Email Country ProdList Advantage
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. 17702719238 17702719238 sales@sun-shinechem.com China 965 64
Heze Development Zone chuangli Chemical Co., Ltd. +86-530-529 6766，+86-15666160102 15666160102 info@chuangli-chem.com China 891 55
Chunchuang (Wuhan) Technology Co., Ltd 15342225168 yutianchun2007@126.com China 9999 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24647 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 sales@chemhifuture.com China 4738 58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd 021-59167510 18117107507 vip@med-life.cn China 4997 58
Supplier Advantage
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. 64
Heze Development Zone chuangli Chemical Co., Ltd. 55
Chunchuang (Wuhan) Technology Co., Ltd 58
TargetMol Chemicals Inc. 58
Nantong QuanYi Biotechnology Co., Ltd 58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd 58
Cyclobutanecarboxylic acid, 3-[(3R)-3-[1-[5-chloro-4-[[(1R)-1-(2,4-dichlorophenyl)ethyl]amino]-6-methyl-2-pyrimidinyl]-3-azetidinyl]-1-piperidinyl]-1-methyl-, trans- RPT193 Zelnecirnon Zelnecirnon (RPT193) 2366152-15-8