ChemicalBook >> CAS DataBase List >>7-CHLORO-1,3DIHYDRO-5-FLUOROPHENYL-2-NITRO-METHYLENE-2H-1,4-BENZODIAZEPINE-4-OXIDE

7-CHLORO-1,3DIHYDRO-5-FLUOROPHENYL-2-NITRO-METHYLENE-2H-1,4-BENZODIAZEPINE-4-OXIDE

CAS No.
60656-76-0
Chemical Name:
7-CHLORO-1,3DIHYDRO-5-FLUOROPHENYL-2-NITRO-METHYLENE-2H-1,4-BENZODIAZEPINE-4-OXIDE
Synonyms
Midazolam Impurity;Midazolam Impurity 11;MIDAZOLAM NITROMETHYLENE COMPOUND;7-CHLORO-1,3DIHYDRO-5-FLUOROPHENYL-2-NITRO-METHYLENE-2H-1,4-BENZODIAZEPINE-4-OXIDE;7-Chloro-1,3-dihydro-5-(2-fluorophenyl)-2-nitromethylene-2H-1,4-benzodiazepine 4-Oxide;7-Chloro-1,3-dihydro-2-nitromethylene-5-(2-fluorophenyl)-2H -1,4-benzodiazepine-4-oxide;7-Chloro-5-(2-fluorophenyl)-2,3-dihydro-2-(nitromethylene)-1H-1,4-benzodiazepine 4-Oxide;1H-1,4-Benzodiazepine, 7-chloro-5-(2-fluorophenyl)-2,3-dihydro-2-(nitromethylene)-, 4-oxide;7-chloro-5-(2-fluorophenyl)-2-(nitromethylene)-2,3-dihydro-1H-benzo[e][1,4]diazepine 4-oxide;(E)-7-chloro-5-(2-fluorophenyl)-2-(nitromethylene)-2,3-dihydro-1H-benzo[e][1,4]diazepine 4-oxide
CBNumber:
CB11230968
Molecular Formula:
C16H11ClFN3O3
Molecular Weight:
347.73
MDL Number:
MOL File:
60656-76-0.mol

7-CHLORO-1,3DIHYDRO-5-FLUOROPHENYL-2-NITRO-METHYLENE-2H-1,4-BENZODIAZEPINE-4-OXIDE Properties

Melting point 240-243 °C(Solv: N,N-dimethylformamide (68-12-2); water (7732-18-5))
Boiling point 539.7±60.0 °C(Predicted)
Density 1.49±0.1 g/cm3(Predicted)
pka -1.18±0.20(Predicted)

7-CHLORO-1,3DIHYDRO-5-FLUOROPHENYL-2-NITRO-METHYLENE-2H-1,4-BENZODIAZEPINE-4-OXIDE Chemical Properties,Uses,Production

Uses

7-Chloro-5-(2-fluorophenyl)-2,3-dihydro-2-(nitromethylene)-1H-1,4-benzodiazepine 4-Oxide is the synthetic precursor of Midazolam (M343000), an anesthetic, anticonvulsant, sedative and hypotic agent.

7-CHLORO-1,3DIHYDRO-5-FLUOROPHENYL-2-NITRO-METHYLENE-2H-1,4-BENZODIAZEPINE-4-OXIDE Preparation Products And Raw materials

Raw materials

Preparation Products

7-CHLORO-1,3DIHYDRO-5-FLUOROPHENYL-2-NITRO-METHYLENE-2H-1,4-BENZODIAZEPINE-4-OXIDE Suppliers

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7-Chloro-5-(2-fluorophenyl)-2,3-dihydro-2-(nitromethylene)-1H-1,4-benzodiazepine 4-Oxide 7-Chloro-1,3dihydro-5-fluorophenyl-2-nitro-methylene-2H-1,4-benzodiazepine-4-oxide (Midazolam inte Midazolam Impurity 11 (E)-7-chloro-5-(2-fluorophenyl)-2-(nitromethylene)-2,3-dihydro-1H-benzo[e][1,4]diazepine 4-oxide 1H-1,4-Benzodiazepine, 7-chloro-5-(2-fluorophenyl)-2,3-dihydro-2-(nitromethylene)-, 4-oxide 7-chloro-5-(2-fluorophenyl)-2-(nitromethylene)-2,3-dihydro-1H-benzo[e][1,4]diazepine 4-oxide 7-Chloro-1,3-dihydro-5-(2-fluorophenyl)-2-nitromethylene-2H-1,4-benzodiazepine 4-Oxide 7-Chloro-1,3-dihydro-2-nitromethylene-5-(2-fluorophenyl)-2H -1,4-benzodiazepine-4-oxide Midazolam Impurity MIDAZOLAM NITROMETHYLENE COMPOUND 7-CHLORO-1,3DIHYDRO-5-FLUOROPHENYL-2-NITRO-METHYLENE-2H-1,4-BENZODIAZEPINE-4-OXIDE 60656-76-0